Bimodal liquid biopsy for cancer immunotherapy based on peptide engineering and nanoscale analysis

A Dual-Channel Intelligent Point-of-Care Testing System for Soluble Programmed Death-1 and Programmed Death-Ligand 1 Detection Based on Folding Paper-Based Immunosensors

(2022) Yu Xing et al.   ACS Sensors

Machine-Learning-Based Clinical Biomarker Using Cell-Free DNA for Hepatocellular Carcinoma (HCC)

(2022) Taehee Lee et al.   Cancers

New electrochemical method for programmed death-ligand 1 detection based on a paper-based microfluidic aptasensor

(2021) Yu Xing et al.   BIOELECTROCHEMISTRY

Tri‐modal liquid biopsy: Combinational analysis of circulating tumor cells, exosomes, and cell‐free DNA using machine learning algorithm

(2021) Jiyoon Bu et al.   Clinical and Translational Medicine

Hierarchically Multivalent Peptide–Nanoparticle Architectures: A Systematic Approach to Engineer Surface Adhesion

(2021) Woo‐jin Jeong et al.   Advanced Science

Nanoparticle Conjugation Stabilizes and Multimerizes β-Hairpin Peptides To Effectively Target PD-1/PD-L1 β-Sheet-Rich Interfaces

(2020) Woo-jin Jeong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2

(2020) Yanxiao Han et al.   ACS Nano

Immunoavidity-Based Capture of Tumor Exosomes Using Poly(amidoamine) Dendrimer Surfaces

(2020) Michael J. Poellmann et al.   NANO LETTERS

Surface engineering for efficient capture of circulating tumor cells in renal cell carcinoma: From nanoscale analysis to clinical application

(2020) Jiyoon Bu et al.   BIOSENSORS & BIOELECTRONICS

An Avidity-Based PD-L1 Antagonist Using Nanoparticle-Antibody Conjugates for Enhanced Immunotherapy

(2020) Jiyoon Bu et al.   NANO LETTERS

Multi-modal liquid biopsy platform for cancer screening: screening both cancer-associated rare cells and cancer cell-derived vesicles on the fabric filters for a reliable liquid biopsy analysis

(2019) Jiyoon Bu et al.   Nano Convergence

Therapeutic peptides: Historical perspectives, current development trends, and future directions

(2018) Jolene L. Lau et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Computational studies of micellar and nanoparticle nanomedicines

(2018) Soumyo Sen et al.   CHEMICAL SOCIETY REVIEWS

Multivalent Binding and Biomimetic Cell Rolling Improves the Sensitivity and Specificity of Circulating Tumor Cell Capture

(2018) Ja Hye Myung et al.   CLINICAL CANCER RESEARCH

The PD-L1 Immunohistochemistry Biomarker: Two Steps Forward, One Step Back?

(2018) Keith M. Kerr   Journal of Thoracic Oncology

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

(2018) H. Halse et al.   Scientific Reports

Dynamic change of PD-L1 expression on circulating tumor cells in advanced solid tumor patients undergoing PD-1 blockade therapy

(2018) Chunyan Yue et al.   OncoImmunology

Anti-PD-1 Antibody SHR-1210 Combined with Apatinib for Advanced Hepatocellular Carcinoma, Gastric, or Esophagogastric Junction Cancer: An Open-label, Dose Escalation and Expansion Study

(2018) Jianming Xu et al.   CLINICAL CANCER RESEARCH

Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)

(2018) Marcin Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism

(2017) Valeria Cagno et al.   NATURE MATERIALS

Design of a Molecular Hybrid of Dual Peptide Inhibitors Coupled on AuNPs for Enhanced Inhibition of Amyloid β-Protein Aggregation and Cytotoxicity

(2017) Neng Xiong et al.   Small

Protein conformational flexibility modulates kinetics and thermodynamics of drug binding

(2017) M. Amaral et al.   Nature Communications

Enhancement of isolation sensitivity for the viable heterogeneous circulating tumor cells swelled by hypo-osmotic pressure

(2017) Jiyoon Bu et al.   RSC Advances

Programmed death-ligand 1 (PD-L1) characterization of circulating tumor cells (CTCs) in muscle invasive and metastatic bladder cancer patients

(2016) Archana Anantharaman et al.   BMC CANCER

Correlation between PD-L1 expression and outcome of NSCLC patients treated with anti-PD-1/PD-L1 agents: A meta-analysis

(2016) Omar Abdel-Rahman   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

PD-L1 Expression in Lung Cancer

(2016) Hui Yu et al.   Journal of Thoracic Oncology

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

(2016) Robert L. Ferris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Liquid biopsies for solid tumors: Understanding tumor heterogeneity and real time monitoring of early resistance to targeted therapies

(2016) Angela Esposito et al.   PHARMACOLOGY & THERAPEUTICS

Hydrocarbon constrained peptides – understanding preorganisation and binding affinity

(2016) Jennifer A. Miles et al.   Chemical Science

Effective Capture of Circulating Tumor Cells from a Transgenic Mouse Lung Cancer Model Using Dendrimer Surfaces Immobilized with Anti-EGFR

(2015) Ja Hye Myung et al.   ANALYTICAL CHEMISTRY

Relative Cosolute Size Influences the Kinetics of Protein-Protein Interactions

(2015) Laurel Hoffman et al.   BIOPHYSICAL JOURNAL

Frequent expression of PD-L1 on circulating breast cancer cells

(2015) Martine Mazel et al.   Molecular Oncology

Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer

(2015) Hossein Borghaei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells

(2015) Joao Paulo Oliveira-Costa et al.   Oncotarget

Multiplexing Natural Orientation: Oppositely Directed Self-Assembling Peptides

(2014) Woo-jin Jeong et al.   BIOMACROMOLECULES

Immune Escape and Survival Mechanisms in Circulating Tumor Cells of Colorectal Cancer

(2014) Gunnar Steinert et al.   CANCER RESEARCH

Coupled Folding and Binding of the Disordered Protein PUMA Does Not Require Particular Residual Structure

(2014) Joseph M. Rogers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Poly(ethylene glycol) Corona Chain Length Controls End-Group-Dependent Cell Interactions of Dendron Micelles

(2014) Hao-jui Hsu et al.   MACROMOLECULES

Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein

(2014) J. M. Rogers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide-based isolation of circulating tumor cells by magnetic nanoparticles

(2014) Linling Bai et al.   Journal of Materials Chemistry B

Interpreting the widespread nonlinear force spectra of intermolecular bonds

(2012) R. W. Friddle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduction of Non-Specific Protein Adsorption Using Poly(ethylene) Glycol (PEG) Modified Polyacrylate Hydrogels In Immunoassays for Staphylococcal Enterotoxin B Detection

(2009) Paul Charles et al.   SENSORS

Covalent functionalization of NiTi surfaces with bioactive peptide amphiphile nanofibers

(2007) Timothy D. Sargeant et al.   BIOMATERIALS

Protein therapeutics: a summary and pharmacological classification

(2007) Benjamin Leader et al.   NATURE REVIEWS DRUG DISCOVERY