Disruption of dual homeostasis by a metal-organic framework nanoreactor for ferroptosis-based immunotherapy of tumor

Nanocatalytic Theranostics with Glutathione Depletion and Enhanced Reactive Oxygen Species Generation for Efficient Cancer Therapy

(2021) Lian‐Hua Fu et al.   ADVANCED MATERIALS

Intracellular Mutual Promotion of Redox Homeostasis Regulation and Iron Metabolism Disruption for Enduring Chemodynamic Therapy

(2021) Yang Liu et al.   ADVANCED FUNCTIONAL MATERIALS

Manganese‐Dioxide‐Coating‐Instructed Plasmonic Modulation of Gold Nanorods for Activatable Duplex‐Imaging‐Guided NIR‐II Photothermal‐Chemodynamic Therapy

(2021) Ting He et al.   ADVANCED MATERIALS

Ferroptosis Photoinduced by New Cyclometalated Iridium(III) Complexes and Its Synergism with Apoptosis in Tumor Cell Inhibition

(2021) Hao Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metabolic Control by Heat Stress Determining Cell Fate to Ferroptosis for Effective Cancer Therapy

(2021) Shaowei Xie et al.   ACS Nano

Protein-Based Nanomedicine for Therapeutic Benefits of Cancer

(2021) Qiuhong Zhang et al.   ACS Nano

Breaking the Redox Homeostasis: an Albumin‐Based Multifunctional Nanoagent for GSH Depletion‐Assisted Chemo‐/Chemodynamic Combination Therapy

(2021) Kaicheng Liang et al.   ADVANCED FUNCTIONAL MATERIALS

Single‐Atom Pd Nanozyme for Ferroptosis‐Boosted Mild‐Temperature Photothermal Therapy

(2021) Mengyu Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Renal Clearable Ultrasmall Single-Crystal Fe Nanoparticles for Highly Selective and Effective Ferroptosis Therapy and Immunotherapy

(2021) Huan Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Metal‐Organic Framework (MOF) Fenton Nanoagent‐Enabled Nanocatalytic Cancer Therapy in Synergy with Autophagy Inhibition

(2020) Bowen Yang et al.   ADVANCED MATERIALS

Equipping Natural Killer Cells with Specific Targeting and Checkpoint Blocking Aptamers for Enhanced Adoptive Immunotherapy in Solid Tumors

(2020) Da Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fenton reaction-independent ferroptosis therapy via glutathione and iron redox couple sequentially triggered lipid peroxide generator

(2020) Yu-Jing He et al.   BIOMATERIALS

Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells

(2020) Chen-Cheng Xue et al.   Science Advances

A Tumor-Targeted Cascade Nanoreactor Based on Metal-Organic-Frameworks for Synergistic Ferroptosis−Starvation Anticancer Therapy

(2020) Xiuyan Wan et al.   ACS Nano

MnO x Nanospikes as Nanoadjuvants and Immunogenic Cell Death Drugs with Enhanced Antitumor Immunity and Antimetastatic Effect

(2020) Binbin Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Nanomedicine Fabricated from Gold Nanoparticles‐Decorated Metal–Organic Framework for Cascade Chemo/Chemodynamic Cancer Therapy

(2020) Yuan Ding et al.   Advanced Science

Redox Dyshomeostasis Strategy for Hypoxic Tumor Therapy Based on DNAzyme‐Loaded Electrophilic ZIFs

(2020) Yanli Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Designer DNA nanostructures for therapeutics

(2020) Shuoxing Jiang et al.   Chem

Nanolongan with Multiple On-Demand Conversions for Ferroptosis–Apoptosis Combined Anticancer Therapy

(2019) Weier Bao et al.   ACS Nano

Glucose Oxidase‐Instructed Multimodal Synergistic Cancer Therapy

(2019) Lian‐Hua Fu et al.   ADVANCED MATERIALS

Targeting Ferroptosis to Iron Out Cancer

(2019) Behrouz Hassannia et al.   CANCER CELL

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

Calcium-Overload-Mediated Tumor Therapy by Calcium Peroxide Nanoparticles

(2019) Meng Zhang et al.   Chem

Biodegradable Nanoprodrugs: “Delivering” ROS to Cancer Cells for Molecular Dynamic Therapy

(2019) Zhong‐min Tang et al.   ADVANCED MATERIALS

Emerging Strategies of Cancer Therapy Based on Ferroptosis

(2018) Zheyu Shen et al.   ADVANCED MATERIALS

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2 -Based Nanoagent to Enhance Chemodynamic Therapy

(2018) Li-Sen Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlled Nucleation and Controlled Growth for Size Predicable Synthesis of Nanoscale Metal-Organic Frameworks (MOFs): A General and Scalable Approach

(2018) Xiao-Gang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects

(2016) Wei-Yun Lai et al.   Molecular Therapy-Nucleic Acids

At the Bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy

(2013) Andrew M. Intlekofer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

High pseudocapacitance of MnO2 nanoparticles in graphitic disordered mesoporous carbon at high scan rates

(2012) Mehul N. Patel et al.   JOURNAL OF MATERIALS CHEMISTRY