Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
出版年份 2021 全文链接
标题
Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
作者
关键词
Genetics, GWAS, Heritability, PheWAS, PTSD, Trauma
出版物
BIOLOGICAL PSYCHIATRY
Volume 91, Issue 7, Pages 626-636
出版商
Elsevier BV
发表日期
2021-09-29
DOI
10.1016/j.biopsych.2021.09.020
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power
- (2021) Elizabeth G. Atkinson et al. NATURE GENETICS
- Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program
- (2021) Murray B. Stein et al. NATURE GENETICS
- Genomic influences on self-reported childhood maltreatment
- (2020) Shareefa Dalvie et al. Translational Psychiatry
- Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies
- (2020) Na Cai et al. HUMAN MOLECULAR GENETICS
- Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts
- (2020) Laura M. Huckins et al. Cell Reports
- Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning
- (2020) Kenneth M. McCullough et al. Nature Communications
- Transcriptomic organization of the human brain in post-traumatic stress disorder
- (2020) Matthew J. Girgenti et al. NATURE NEUROSCIENCE
- Clinical use of current polygenic risk scores may exacerbate health disparities
- (2019) Alicia R. Martin et al. NATURE GENETICS
- Reverse GWAS: Using genetics to identify and model phenotypic subtypes
- (2019) Andy Dahl et al. PLoS Genetics
- Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans
- (2019) Joel Gelernter et al. NATURE NEUROSCIENCE
- Genetic mapping of cell type specificity for complex traits
- (2019) Kyoko Watanabe et al. Nature Communications
- Posttranscriptional Gene Regulation of the GABA Receptor to Control Neuronal Inhibition
- (2019) Rico Schieweck et al. Frontiers in Molecular Neuroscience
- RICOPILI: Rapid Imputation for COnsortias PIpeLIne
- (2019) Max Lam et al. BIOINFORMATICS
- Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness
- (2019) Abdel Abdellaoui et al. HUMAN MOLECULAR GENETICS
- A global overview of pleiotropy and genetic architecture in complex traits
- (2019) Kyoko Watanabe et al. NATURE GENETICS
- TRIM27 promotes the proliferation and inflammation factor production induced by IL-6 by activating STAT3 signaling in HaCaT cells
- (2019) Xiao Miao et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration
- (2019) Andric C. Perez-Ortiz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
- (2019) Caroline M. Nievergelt et al. Nature Communications
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
- (2019) Phil H. Lee et al. CELL
- Psychiatric Genomics: An Update and an Agenda
- (2018) Patrick F. Sullivan et al. AMERICAN JOURNAL OF PSYCHIATRY
- Mixed-model association for biobank-scale datasets
- (2018) Po-Ru Loh et al. NATURE GENETICS
- Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways
- (2018) Mats Nagel et al. NATURE GENETICS
- Multi-trait analysis of genome-wide association summary statistics using MTAG
- (2018) Patrick Turley et al. NATURE GENETICS
- The membrane palmitoylated protein, MPP6, is involved in myelin formation in the mouse peripheral nervous system
- (2018) Yurika Saitoh et al. HISTOCHEMISTRY AND CELL BIOLOGY
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
- (2018) Ditte Demontis et al. NATURE GENETICS
- A polygenic p factor for major psychiatric disorders
- (2018) Saskia Selzam et al. Translational Psychiatry
- Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability
- (2017) L E Duncan et al. MOLECULAR PSYCHIATRY
- Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis
- (2017) Kazuyoshi Ishigaki et al. NATURE GENETICS
- Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
- (2017) Suzanne Sniekers et al. NATURE GENETICS
- Posttraumatic stress disorder in the World Mental Health Surveys
- (2017) K. C. Koenen et al. PSYCHOLOGICAL MEDICINE
- Genomic analysis–integrated whole-exome sequencing of neuroblastomas identifies genetic mutations in axon guidance pathway
- (2017) Yuanyuan Li et al. Oncotarget
- Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls
- (2017) Rajendra A. Morey et al. Translational Psychiatry
- Posttraumatic Stress Disorder in Adults: Impact, Comorbidity, Risk Factors, and Treatment
- (2017) Jitender Sareen CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
- LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
- (2016) Jie Zheng et al. BIOINFORMATICS
- The neurobiology of emotion regulation in posttraumatic stress disorder: Amygdala downregulation via real-time fMRI neurofeedback
- (2016) Andrew A. Nicholson et al. HUMAN BRAIN MAPPING
- Fast and efficient QTL mapper for thousands of molecular phenotypes
- (2015) Halit Ongen et al. BIOINFORMATICS
- A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project
- (2015) Latarsha J. Carithers et al. BIOPRESERVATION AND BIOBANKING
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration
- (2015) Mark W Logue et al. NEUROPSYCHOPHARMACOLOGY
- The epidemiology of traumatic event exposure worldwide: results from the World Mental Health Survey Consortium
- (2015) C. Benjet et al. PSYCHOLOGICAL MEDICINE
- A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project
- (2015) Latarsha J. Carithers et al. Biopreservation and Biobanking
- MAGMA: Generalized Gene-Set Analysis of GWAS Data
- (2015) Christiaan A. de Leeuw et al. PLoS Computational Biology
- TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3
- (2015) Peng Wang et al. PLoS Pathogens
- Post-traumatic stress disorder
- (2015) Rachel Yehuda et al. Nature Reviews Disease Primers
- A Unification of Mediation and Interaction
- (2014) Tyler J. VanderWeele EPIDEMIOLOGY
- Reduced Amygdala and Ventral Striatal Activity to Happy Faces in PTSD Is Associated with Emotional Numbing
- (2014) Kim L. Felmingham et al. PLoS One
- Common Heritable Contributions to Low-Risk Trauma, High-Risk Trauma, Posttraumatic Stress Disorder, and Major Depression
- (2012) Carolyn E. Sartor ARCHIVES OF GENERAL PSYCHIATRY
- The 1000 Genomes Project: data management and community access
- (2012) Laura Clarke et al. NATURE METHODS
- Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses
- (2012) Oliver Stegle et al. Nature Protocols
- Biological studies of post-traumatic stress disorder
- (2012) Roger K. Pitman et al. NATURE REVIEWS NEUROSCIENCE
- Genotype Imputation with Thousands of Genomes
- (2011) Bryan Howie et al. G3-Genes Genomes Genetics
- LocusZoom: regional visualization of genome-wide association scan results
- (2010) R. J. Pruim et al. BIOINFORMATICS
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- Genetics of Post-Traumatic Stress Disorder: Review and Recommendations for Genome-Wide Association Studies
- (2010) Marilyn C. Cornelis et al. Current Psychiatry Reports
- Human-specific transcriptional regulation of CNS development genes by FOXP2
- (2009) Genevieve Konopka et al. NATURE
- Shape-IT: new rapid and accurate algorithm for haplotype inference
- (2008) Olivier Delaneau et al. BMC BIOINFORMATICS
- The role of trauma-related distractors on neural systems for working memory and emotion processing in posttraumatic stress disorder
- (2008) Rajendra A. Morey et al. JOURNAL OF PSYCHIATRIC RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started