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Recent advances for cancer detection and treatment by microfluidic technology, review and update

期刊

BIOLOGICAL PROCEDURES ONLINE
卷 24, 期 1, 页码 -

出版社

BMC
DOI: 10.1186/s12575-022-00166-y

关键词

Microfluidic; Laminar flow; Tumour; Metastasis

资金

  1. Biotechnology Development Council of the Islamic Republic of Iran
  2. Tabriz University of medical science, Tabriz, Iran

向作者/读者索取更多资源

Microfluidic systems provide a precise and user-friendly technique for cancer diagnosis and treatment, with high sensitivity, high throughput, and low cost. Although not yet widely used in clinical settings, they are expected to become the main technology for cancer diagnosis and treatment, offering more sensitive and accurate detection of cancer biomarkers and therapeutic strategies. Microfluidic lab-on-a-chip platforms have shown remarkable potential in designing novel procedures for cancer detection, therapy, and disease follow-up, as well as in developing new drug delivery systems for cancer treatment.
Numerous cancer-associated deaths are owing to a lack of effective diagnostic and therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a precise, quick, and user-friendly technique for cancer diagnosis and treatment. Microfluidic devices can detect many cancer-diagnostic factors from biological fluids and also generate appropriate nanoparticles for drug delivery. Thus, microfluidics may be valuable in the cancer field due to its high sensitivity, high throughput, and low cost. In the present article, we aim to review recent achievements in the application of microfluidic systems for the diagnosis and treatment of various cancers. Although microfluidic platforms are not yet used in the clinic, they are expected to become the main technology for cancer diagnosis and treatment. Microfluidic systems are proving to be more sensitive and accurate for the detection of cancer biomarkers and therapeutic strategies than common assays. Microfluidic lab-on-a-chip platforms have shown remarkable potential in the designing of novel procedures for cancer detection, therapy, and disease follow-up as well as the development of new drug delivery systems for cancer treatment.

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