标题
Is the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases?
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 17, Issue 8, Pages 1236
出版商
MDPI AG
发表日期
2016-08-03
DOI
10.3390/ijms17081236
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Familial partial lipodystrophy linked to a novel peroxisome proliferator activator receptor -γ (PPARG) mutation, H449L: a comparison of people with this mutation and those with classic codon 482 Lamin A/C (LMNA) mutations
- (2016) T. Demir et al. DIABETIC MEDICINE
- Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes
- (2016) Yisheng Yang et al. ENDOCRINE REVIEWS
- New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr−/− mice
- (2016) Jacqueline C. Silva et al. PHARMACOLOGICAL RESEARCH
- Metabolic syndrome update
- (2016) Scott M. Grundy TRENDS IN CARDIOVASCULAR MEDICINE
- Emerging Roles of Adipose Progenitor Cells in Tissue Development, Homeostasis, Expansion and Thermogenesis
- (2016) Daniel C. Berry et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome
- (2016) Milana Kokosar et al. Scientific Reports
- Impact of the C1431T Polymorphism of the Peroxisome Proliferator Activated Receptor-Gamma (PPAR-γ) Gene on Fasted Serum Lipid Levels in Patients with Coronary Artery Disease
- (2015) Mohammadreza Oladi et al. ANNALS OF NUTRITION AND METABOLISM
- IGF2, LEPR, POMC, PPARG, and PPARGC1 gene variants are associated with obesity-related risk phenotypes in Brazilian children and adolescents
- (2015) E.M. Queiroz et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo
- (2015) Raymond E. Soccio et al. CELL
- Novel peroxisome proliferator-activated receptor gamma mutation in a family with familial partial lipodystrophy type 3
- (2015) Konstanze Miehle et al. CLINICAL ENDOCRINOLOGY
- A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice
- (2015) Yoshihiro Shiomi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Variation inPPARGIs Associated With Longitudinal Change in Insulin Resistance in Mexican Americans at Risk for Type 2 Diabetes
- (2015) Mary Helen Black et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes
- (2014) E. Nilsson et al. DIABETES
- Biallelic mutations at PPARG cause a congenital, generalized lipodystrophy similar to the Berardinelli–Seip syndrome
- (2014) D.A. Dyment et al. European Journal of Medical Genetics
- Association of the variants in thePPARGgene and serum lipid levels: a meta-analysis of 74 studies
- (2014) Qing Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Agonistic induction of PPARγ reverses cigarette smoke–induced emphysema
- (2014) Ming Shan et al. JOURNAL OF CLINICAL INVESTIGATION
- An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ
- (2014) Alexander S. Banks et al. NATURE
- Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
- (2014) A. R. Majithia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose Homeostasis
- (2014) Yuwei Jiang et al. Cell Reports
- Peroxisome Proliferator-Activated Receptor-γ Mutations Responsible for Lipodystrophy With Severe Hypertension Activate the Cellular Renin–Angiotensin System
- (2013) Martine Auclair et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Different effects of PPARA, PPARG and ApoE SNPs on serum lipids in patients with coronary heart disease based on the presence of diabetes
- (2013) Hulya Yilmaz-Aydogan et al. GENE
- Common Genetic Variants in Peroxisome Proliferator-Activated Receptor-γ (PPARG) and Type 2 Diabetes Risk Among Women's Health Initiative Postmenopausal Women
- (2013) Kei Hang K. Chan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- PPARγ signaling and metabolism: the good, the bad and the future
- (2013) Maryam Ahmadian et al. NATURE MEDICINE
- Pro12Ala variant of thePPARG2gene increases body mass index: An updated meta-analysis encompassing 49,092 subjects
- (2013) C. Galbete et al. Obesity
- The Pro12Ala Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma-2 Gene (PPARγ2) Is Associated with Increased Risk of Coronary Artery Disease: A Meta-Analysis
- (2013) Zhijun Wu et al. PLoS One
- Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci
- (2012) Folkert W. Asselbergs et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Rosiglitazone Promotes PPARγ-Dependent and -Independent Alterations in Gene Expression in Mouse Islets
- (2012) Hannah J. Welters et al. ENDOCRINOLOGY
- Thiazolidinedione safety
- (2012) Jacqueline Kung et al. Expert Opinion On Drug Safety
- Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography
- (2012) Kikuko Hotta et al. JOURNAL OF HUMAN GENETICS
- A PPARγ–FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis
- (2012) Johan W. Jonker et al. NATURE
- Nuclear Hormone Receptors Enable Macrophages and Dendritic Cells to Sense Their Lipid Environment and Shape Their Immune Response
- (2012) Laszlo Nagy et al. PHYSIOLOGICAL REVIEWS
- Systemic PPARγ Deletion Impairs Circadian Rhythms of Behavior and Metabolism
- (2012) Guangrui Yang et al. PLoS One
- PPARs: Fatty acid sensors controlling metabolism
- (2012) Lars la Cour Poulsen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Cross species comparison of C/EBPα and PPARγ profiles in mouse and human adipocytes reveals interdependent retention of binding sites
- (2011) Søren F Schmidt et al. BMC GENOMICS
- Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass
- (2011) Yurena Vivas et al. BMC Medical Genomics
- Lipodystrophies: Genetic and Acquired Body Fat Disorders
- (2011) Abhimanyu Garg JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Interaction ofPPARGPro12Ala with dietary fat influences plasma lipids in subjects at cardiometabolic risk
- (2011) Aseel AlSaleh et al. JOURNAL OF LIPID RESEARCH
- Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients with and without Type 2 diabetes
- (2011) Hulya Yilmaz-Aydogan et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- A role for central nervous system PPAR-γ in the regulation of energy balance
- (2011) Karen K Ryan et al. NATURE MEDICINE
- Lipid-sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome
- (2011) Michele Vacca et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Genetic polymorphisms in diabetes: Influence on therapy with oral antidiabetics
- (2010) Una Glamočlija et al. ACTA PHARMACEUTICA
- The Association Between the Peroxisome Proliferator-Activated Receptor-γ2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis
- (2010) Hebe N. Gouda et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia
- (2010) D. Capaccio et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Comparative Epigenomic Analysis of Murine and Human Adipogenesis
- (2010) Tarjei S. Mikkelsen et al. CELL
- Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferator-activated receptor-γ (PPAR-γ)-deficient mice
- (2010) S. Z. Duan et al. DIABETOLOGIA
- PPARγ in Placental Angiogenesis
- (2010) Karim Nadra et al. ENDOCRINOLOGY
- Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients
- (2010) Alisa K. Manning et al. GENETIC EPIDEMIOLOGY
- STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells
- (2010) Attila Szanto et al. IMMUNITY
- Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
- (2010) Jang Hyun Choi et al. NATURE
- The Pro12Ala PPARγ2 Variant Determines Metabolism at the Gene-Environment Interface
- (2009) Sami Heikkinen et al. Cell Metabolism
- The PPARγ Pro12Ala variant is associated with insulin sensitivity in Russian normoglycaemic and type 2 diabetic subjects
- (2009) Dimitry A. Chistiakov et al. Diabetes & Vascular Disease Research
- Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study
- (2009) S.-M. Ruchat et al. DIABETOLOGIA
- Evidence for Interaction betweenPPARGPro12Ala andPPARGC1AGly482Ser Polymorphisms in Determining Type 2 Diabetes Intermediate Phenotypes in Overweight Subjects
- (2009) S.-M. Ruchat et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor
- (2009) Dharambir Kaur Sanghera et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- PPARG Genotype Accounts for Part of Individual Variation in Body Weight Reduction in Response to Calorie Restriction
- (2009) Tomoaki Matsuo et al. Obesity
- Posttranslational Modifications of PPAR-γ: Fine-tuning the Metabolic Master Regulator
- (2009) Olivier van Beekum et al. Obesity
- PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 Are Associated with Type 2 Diabetes in a Chinese Population
- (2009) Cheng Hu et al. PLoS One
- PPARγ activation in adipocytes is sufficient for systemic insulin sensitization
- (2009) Shigeki Sugii et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fat and Beyond: The Diverse Biology of PPARγ
- (2008) Peter Tontonoz et al. Annual Review of Biochemistry
- PPARgamma Promoter Polymorphisms and Acute Coronary Syndrome
- (2008) L. Evangelisti et al. ATHEROSCLEROSIS
- In Vivoandin VitroStudies of a Functional Peroxisome Proliferator-activated Receptor γ Response Element in the Mousepdx-1Promoter
- (2008) Dhananjay Gupta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA
- (2008) Vikas Chandra et al. NATURE
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