Editorial Material
Polymer Science
Alexander S. Novikov
Summary: Non-covalent interactions are a key topic in modern chemical science, with significant effects on the properties of polymers. This Special Issue collects fundamental and applied research papers focused on non-covalent interactions in polymer chemistry and related fields, including original research articles and comprehensive review papers. The scope of the Special Issue is broad, welcoming contributions on the synthesis, structure, functionality, and properties of polymer systems involving non-covalent interactions.
Article
Chemistry, Multidisciplinary
Na Wang, Jingkang Wang, Xin Huang, Ting Wang, Xin Li, Jinyue Yang, Ying Bao, Qiuxiang Yin, Hongxun Hao
Summary: The study introduces a novel method for separating and purifying isomer mixtures using selective cocrystallization technology, which demonstrates efficient selectivity and broad applicability for different types of mixtures. The nature of selective recognition for cocrystallization was confirmed in both solution and solid states, indicating the feasibility and potential of this new SCoC technology as a method for isomer separation.
Article
Chemistry, Multidisciplinary
Benjamin J. Huffman, Tiffany Chu, Yusuke Hanaki, Jonathan J. Wong, Shuming Chen, Kendall N. Houk, Ryan A. Shenvi
Summary: A strategy to control the diastereoselectivity of bond formation at a prochiral attached-ring bridgehead was reported, using basic vs. Lewis acidic conditions and non-covalent interactions to achieve facial selectivity. The successful synthesis of an erythro subtarget diastereomer ultimately led to a short formal synthesis of merrilactone A.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Alhadji Malloum, Jeanet Conradie
Summary: This study investigated the structures and non-covalent interactions in thiophene clusters using quantum chemical computations and classical molecular dynamics. Six different non-covalent interactions were identified in thiophene clusters. The performance of eleven functionals in calculating the binding energies of thiophene clusters was assessed, with the functionals M052X and M06 showing the best performance.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Polymer Science
Laura Nicolle, Celine M. A. Journot, Sandrine Gerber-Lemaire
Summary: Chitosan, a natural biopolymer, has attracted great interest in research fields due to its biocompatibility, biodegradability, and mechanical properties. Various types of chemical modifications, including covalent and non-covalent methods, have been applied to improve its properties. Characterization techniques for chitosan derivatives are also important in determining their composition and physical properties.
Article
Chemistry, Multidisciplinary
Deepak Badgurjar, Madison Huynh, Benjamin Masters, Anna Wuttig
Summary: We report a synthetic strategy that allows for the molecular definition of electrified interfaces independent of the electrode's surface chemistry. By appending ferrocene redox reporters to amphiphiles, we achieve a self-assembled layer stable over a wide voltage range. The design is reversible and can be applied across various electrode materials and morphologies.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Haia Kharraz, Hadi Hachem, Yann Le Gal, Thierry Roisnel, Olivier Jeannin, Frederic Barriere, Thierry Guizouarn, Dominique Lorcy
Summary: Tetrathiafulvalenes (TTFs) were functionalized with groups that enhance non-covalent intermolecular interactions. The study involved designing appropriate precursors and assessing the electronic effect of the substituents on the overall donating ability of the TTFs. Charge transfer salts were prepared and their crystal structures were analyzed to understand the stacking mode and non-covalent interactions in the solid state.
Article
Multidisciplinary Sciences
Anthony C. Yu, Huada Lian, Xian Kong, Hector Lopez Hernandez, Jian Qin, Eric A. Appel
Summary: Studies suggest that entropy-driven physical networks exhibit invariant mechanical properties at elevated temperatures, in contrast to enthalpy-dominated crosslinking networks. By connecting thermodynamics and temperature-dependent viscoelasticity in a mathematical framework, the temperature dependence of crosslinking interactions is explored.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Chad Plumet, Achmet Said Mohamed, Tanguy Vendeuvre, Brigitte Renoux, Jonathan Clarhaut, Sebastien Papot
Summary: Metabolic glycoengineering with unnatural sugars is used to introduce recognition markers on cell membranes via bioorthogonal chemistry, functionalizing tumor and T cell surfaces. These artificial markers induce cell-cell adhesion and activate natural killer cells, ultimately leading to cancer cell cytolysis. This study's surface markers offer a simple way to investigate and manipulate intercellular interactions on a wide range of cells.
Article
Chemistry, Analytical
Xiaohan Chen, Youwen Zhang, Pearl Arora, Xiyun Guan
Summary: Different species can be detected using nanopores engineered with various recognition sites based on non-covalent interactions. This strategy allows for differentiation between species, making it potentially useful for molecular detection in medical and environmental applications.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
David B. Hobart, Michael A. G. Berg, Hannah M. Rogers, Joseph S. Merola
Summary: The reaction of palladium(II) acetate with acyclic amino acids in acetone/water produces square planar bis-chelated palladium amino acid complexes with interesting non-covalent interactions. The molecular structures of the products, including the incorporation of water molecules and N-H···O and/or O···(HOH)···O hydrogen bonding interactions, were discussed in terms of the extended lattice structures exhibited by the complexes. Multiple spectroscopic techniques were used for analysis, with some cases allowing for single crystal X-ray diffraction to obtain the molecular structure.
Article
Crystallography
Diego Ramirez-Contreras, Amalia Garcia-Garcia, Brenda L. Sanchez-Gaytan, Laura E. Serrano-de la Rosa, Francisco J. Melendez, Duane Choquesillo-Lazarte, Antonio Rodriguez-Dieguez, Maria Eugenia Castro, Enrique Gonzalez-Vergara
Summary: Citrulline is a non-protein amino acid found in watermelon. Researchers synthesized and characterized a copper bis-citrullinato complex and found its polymeric nature and insolubility make it unsuitable for potential anticancer chemicals. However, the facile synthesis of D-Citrulline could open up new applications for this interesting amino acid.
Editorial Material
Crystallography
Alexander S. Novikov
Summary: This editorial announces a special issue on the theoretical investigation of non-covalent interactions in crystals. The special issue covers the latest progress in data science, artificial intelligence, quantum and computational chemistry, and highlights the main successes in the field of fundamental theoretical studies of non-covalent interactions over the past year.
Article
Chemistry, Multidisciplinary
Jiayong Lu, Junran Wu, Bin Huang, Yu Fang, Xiangmeng Deng, Jialin Zhang, Shanshan Chen, Seonghun Jeong, Jinbiao Liu, Changduk Yang
Summary: Ternary polymerization is a feasible method to optimize the properties of polymer matrix. By introducing the DDT unit as the third component, two terpolymer donors, L1 and L2, with deeper energy levels, enhanced molecular rigidity, and planarity are developed. The L1-based polymer solar cells blended with L8-BO exhibit well-defined nanofibrous morphology, face-on orientation, and record power conversion efficiency of up to 18.75%.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Max Lallemang, Leixiao Yu, Wanhao Cai, Klaus Rischka, Andreas Hartwig, Rainer Haag, Thorsten Hugel, Bizan N. Balzer
Summary: This study investigates the strength and characteristics of multivalent interactions at the molecular level using AFM technology, and finds that under certain conditions, non-covalent bonds, such as coordination bonds, can exhibit higher multivalent bond strength, even surpassing strong covalent bonds. Additionally, covalent bonds enhance the density of the multifunctional polymer layer, particularly increasing the number of non-covalent bonds.
Article
Chemistry, Multidisciplinary
Charles C. J. Loh, Xiang Fang, Brendan Peters, Mark Lautens
CHEMISTRY-A EUROPEAN JOURNAL
(2015)
Article
Chemistry, Organic
Suruchi Mahajan, Pankaj Chauhan, Charles C. J. Loh, Server Uzungelis, Gerhard Raabe, Dieter Enders
SYNTHESIS-STUTTGART
(2015)
Article
Chemistry, Multidisciplinary
Charles C. J. Loh, Matthias Schmid, Robert Webster, Andy Yen, Shabnam K. Yazdi, Patrick T. Franke, Mark Lautens
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2016)
Article
Chemistry, Multidisciplinary
Charles C. J. Loh, Matthias Schmid, Brendan Peters, Xiang Fang, Mark Lautens
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2016)
Article
Chemistry, Applied
Charles C. J. Loh, Pankaj Chauhan, Daniel Hack, Christian Lehmann, Dieter Enders
ADVANCED SYNTHESIS & CATALYSIS
(2014)
Article
Chemistry, Multidisciplinary
Charles C. J. Loh, Daniel Hack, Dieter Enders
CHEMICAL COMMUNICATIONS
(2013)
Article
Chemistry, Multidisciplinary
Daniel Hack, Charles C. J. Loh, Jan M. Hartmann, Gerhard Raabe, Dieter Enders
CHEMISTRY-A EUROPEAN JOURNAL
(2014)
Article
Chemistry, Organic
Pankaj Chauhan, Suruchi Mahajan, Charles C. J. Loh, Gerhard Raabe, Dieter Enders
Article
Multidisciplinary Sciences
Chunfa Xu, Charles C. J. Loh
NATURE COMMUNICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Chunfa Xu, Charles C. J. Loh
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Article
Multidisciplinary Sciences
Chunfa Xu, V. U. Bhaskara Rao, Julia Weigen, Charles C. J. Loh
NATURE COMMUNICATIONS
(2020)
Article
Chemistry, Multidisciplinary
V. U. Bhaskara Rao, Caiming Wang, Daniel P. Demarque, Corentin Grassin, Felix Otte, Christian Merten, Carsten Strohmann, Charles C. J. Loh
Summary: Site-selective functionalization is a significant synthetic strategy in organic synthesis. Chiral catalysis has been used to control the site selectivity in complex carbohydrate functionalizations, providing new routes to biologically relevant glycosides. However, the availability of robust catalytic systems to overcome multiple stereoselectivity challenges remains limited. In this study, we present a synergistic chiral Rh(I)- and organoboron-catalysed protocol for the synthesis of challenging but biologically relevant arylnaphthalene glycosides. Our method employs chiral Rh(I) catalysis for site-selective carbohydrate functionalization and demonstrates the utility of boronic acid as a compatible co-catalyst. The success of our method depends on the judicious choice of a suitable organoboron catalyst, and we show that multiple aspects of stereocontrol are simultaneously operative.
Article
Chemistry, Multidisciplinary
Wenpeng Ma, Jan-Lukas Kirchhoff, Carsten Strohmann, Bastian Grabe, Charles C. J. Loh
Summary: The utilization of noncovalent interactions (NCIs) in synthesis to overcome broad stereoselectivity challenges is gaining importance, with particular interest in unconventional bifurcated chalcogen bonding and hydrogen bonding networks for glycosylation reactions. By combining experimental and theoretical approaches, this study demonstrates the simultaneous activation of bifurcated chalcogen bonding and hydrogen bonding, providing a robust catalytic strategy for the synthesis of biologically active seven-membered ring sugars.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Andy Yen, Ken-Loon Choo, Shabnam K. Yazdi, Patrick T. Franke, Robert Webster, Ivan Franzoni, Charles C. J. Loh, Amalia I. Poblador-Bahamonde, Mark Lautens
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2017)