Nanoantibiotics Based in Mesoporous Silica Nanoparticles: New Formulations for Bacterial Infection Treatment
出版年份 2021 全文链接
标题
Nanoantibiotics Based in Mesoporous Silica Nanoparticles: New Formulations for Bacterial Infection Treatment
作者
关键词
-
出版物
Pharmaceutics
Volume 13, Issue 12, Pages 2033
出版商
MDPI AG
发表日期
2021-12-01
DOI
10.3390/pharmaceutics13122033
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inorganic and Polymeric Nanoparticles for Human Viral and Bacterial Infections Prevention and Treatment
- (2021) John Jairo Aguilera-Correa et al. Nanomaterials
- Designing Mesoporous Silica Nanoparticles to Overcome Biological Barriers by Incorporating Targeting and Endosomal Escape
- (2021) Miguel Gisbert-Garzarán et al. ACS Applied Materials & Interfaces
- Membrane Interactions of Virus-like Mesoporous Silica Nanoparticles
- (2021) Sara Malekkhaiat Häffner et al. ACS Nano
- Nanoantibiotics: Functions and Properties at the Nanoscale to Combat Antibiotic Resistance
- (2021) M. Mustafa Mamun et al. Frontiers in Chemistry
- A versatile multicomponent mesoporous silica nanosystem with dual antimicrobial and osteogenic effects
- (2021) Elena Álvarez et al. Acta Biomaterialia
- Bacterial Outer Membrane‐Coated Mesoporous Silica Nanoparticles for Targeted Delivery of Antibiotic Rifampicin against Gram‐Negative Bacterial Infection In Vivo
- (2021) Shuang Wu et al. ADVANCED FUNCTIONAL MATERIALS
- Recent Advances Toward the Use of Mesoporous Silica Nanoparticles for the Treatment of Bacterial Infections
- (2021) Rafael R Castillo et al. International Journal of Nanomedicine
- Can mesoporous nanoparticles promote bioavailability of topical pharmaceutics?
- (2021) Sabrina Valetti et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Scalable synthesis of multicomponent multifunctional inorganic core@mesoporous silica shell nanocomposites
- (2021) Muling Zeng et al. Materials Science & Engineering C-Materials for Biological Applications
- Virus-like mesoporous silica-coated plasmonic Ag nanocube with strong bacteria adhesion for diabetic wound ulcer healing
- (2021) Peiyuan Wang et al. Nanomedicine-Nanotechnology Biology and Medicine
- Delivery by Dendritic Mesoporous Silica Nanoparticles Enhances the Antimicrobial Activity of a Napsin‐Derived Peptide Against Intracellular Mycobacterium tuberculosis
- (2021) Bastian Beitzinger et al. Advanced Healthcare Materials
- Osteoporosis Remission and New Bone Formation with Mesoporous Silica Nanoparticles
- (2021) Patricia Mora‐Raimundo et al. Advanced Science
- Our contributions to applications of mesoporous silica nanoparticles
- (2021) María Vallet-Regí Acta Biomaterialia
- Arabic gum plus colistin coated moxifloxacin-loaded nanoparticles for the treatment of bone infection caused by Escherichia coli
- (2021) J.J. Aguilera-Correa et al. Acta Biomaterialia
- Mesoporous silica nanoparticles for pulmonary drug delivery
- (2021) Alba García-Fernández et al. ADVANCED DRUG DELIVERY REVIEWS
- Effective reduction of biofilm through photothermal therapy by gold core@shell based mesoporous silica nanoparticles
- (2021) Ana García et al. MICROPOROUS AND MESOPOROUS MATERIALS
- Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis
- (2020) Miguel Gisbert-Garzarán et al. Pharmaceutics
- Biomaterials against Bone Infection
- (2020) María Vallet‐Regí et al. Advanced Healthcare Materials
- Mesoporous Silica Nanoparticles as Carriers for Therapeutic Biomolecules
- (2020) Rafael R. Castillo et al. Pharmaceutics
- Amino-Functionalized Mesoporous Silica Nanoparticle-Encapsulated Octahedral Organoruthenium Complex as an Efficient Platform for Combatting Cancer
- (2020) Marina Martínez-Carmona et al. INORGANIC CHEMISTRY
- Tailoring Nanoparticle-Biofilm Interactions to Increase the Efficacy of Antimicrobial Agents Against Staphylococcus aureus
- (2020) Stephanie Fulaz et al. International Journal of Nanomedicine
- Advances in Laser Ablation Synthesized Silicon-Based Nanomaterials for the Prevention of Bacterial Infection
- (2020) Marina Martínez-Carmona et al. Nanomaterials
- Silica Nanoparticles—A Versatile Tool for the Treatment of Bacterial Infections
- (2020) Vanitha Selvarajan et al. Frontiers in Chemistry
- Phytochemical Curcumin-Coformulated, Silver-Decorated Melanin-like Polydopamine/Mesoporous Silica Composites with Improved Antibacterial and Chemotherapeutic Effects against Drug-Resistant Cancer Cells
- (2020) Yiyan Song et al. ACS Omega
- Mesoporous silica nanoparticles: facile surface functionalization and versatile biomedical applications in oncology
- (2020) Rui Huang et al. Acta Biomaterialia
- Mesoporous silica nanoparticles containing silver as novel antimycobacterial agents against Mycobacterium tuberculosis
- (2020) Sandra Montalvo-Quirós et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Production of MCM-41 Nanoparticles with Control of Particle Size and Structural Properties: Optimizing Operational Conditions during Scale-Up
- (2020) Rafael R. Castillo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Highlights in Mesoporous Silica Nanoparticles as a Multifunctional Controlled Drug Delivery Nanoplatform for Infectious Diseases Treatment
- (2020) Gabriela Corrêa Carvalho et al. PHARMACEUTICAL RESEARCH
- Targeted Stimuli-Responsive Mesoporous Silica Nanoparticles for Bacterial Infection Treatment
- (2020) Montserrat Colilla et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Exploiting mesoporous silica nanoparticles as versatile drug carriers for several routes of administration
- (2020) Rafael Miguel Sábio et al. MICROPOROUS AND MESOPOROUS MATERIALS
- Impact of the antibiotic-cargo from MSNs on gram-positive and gram-negative bacterial biofilms
- (2020) Anna Aguilar-Colomer et al. MICROPOROUS AND MESOPOROUS MATERIALS
- SILAC-based quantitative proteomics identifies size-dependent molecular mechanisms involved in silver nanoparticles-induced toxicity
- (2019) M. N. Fernández et al. Nanotoxicology
- 2018 international consensus meeting on musculoskeletal infection: Summary from the biofilm workgroup and consensus on biofilm related musculoskeletal infections
- (2019) Kordo Saeed et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: an update
- (2019) Rafael R. Castillo et al. Expert Opinion on Drug Delivery
- Nanoparticles to Knockdown Osteoporosis-Related Gene and Promote Osteogenic Marker Expression for Osteoporosis Treatment
- (2019) Patricia Mora-Raimundo et al. ACS Nano
- 2018 International Consensus Meeting on Musculoskeletal Infection: Research Priorities from the General Assembly Questions
- (2019) Edward M. Schwarz et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Mesoporous Silica‐Based Materials with Bactericidal Properties
- (2019) Andrea Bernardos et al. Small
- MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis
- (2019) Nicole E. Putnam et al. PLoS Pathogens
- Concanavalin A-targeted mesoporous silica nanoparticles for infection treatment
- (2019) Marina Martínez-Carmona et al. Acta Biomaterialia
- Nanomaterials as Promising Alternative in the Infection Treatment
- (2019) María Vallet-Regí et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Controllable delivery from gentamicin loaded polycaprolactone/grafted silica nanoparticles composite mats
- (2019) Sarah Tariq et al. JOURNAL OF MOLECULAR LIQUIDS
- Synthetic α-l-Threose Nucleic Acids Targeting BcL-2 Show Gene Silencing and in Vivo Antitumor Activity for Cancer Therapy
- (2019) Fei Wang et al. ACS Applied Materials & Interfaces
- Integration of diagnosis and treatment in the detection and kill of S.aureus in the whole blood
- (2019) Tingting Xu et al. BIOSENSORS & BIOELECTRONICS
- Nanoparticles for multimodal antivascular therapeutics: Dual drug release, photothermal and photodynamic therapy
- (2019) Juan L. Paris et al. Acta Biomaterialia
- Antibacterial and anticancer activities of asymmetric lollipop-like mesoporous silica nanoparticles loaded with curcumin and gentamicin sulfate
- (2019) Yajun Cheng et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Self-enriched mesoporous silica nanoparticle composite membrane with remarkable photodynamic antimicrobial performances
- (2019) Jing Sun et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Beyond Traditional Hyperthermia: In Vivo Cancer Treatment with Magnetic-Responsive Mesoporous Silica Nanocarriers
- (2018) Eduardo Guisasola et al. ACS Applied Materials & Interfaces
- Bacteria-Targeting Nanoparticles with Microenvironment-Responsive Antibiotic Release To Eliminate Intracellular Staphylococcus aureus and Associated Infection
- (2018) Shengbing Yang et al. ACS Applied Materials & Interfaces
- Lectin-conjugated pH-responsive mesoporous silica nanoparticles for targeted bone cancer treatment
- (2018) Marina Martínez-Carmona et al. Acta Biomaterialia
- Mesoporous silica nanoparticles decorated with polycationic dendrimers for infection treatment
- (2018) Blanca González et al. Acta Biomaterialia
- Improving the Antimicrobial Power of Low-Effective Antimicrobial Molecules Through Nanotechnology
- (2018) María Ruiz-Rico et al. JOURNAL OF FOOD SCIENCE
- Rifampin Stability and Solution Concentration Enhancement Through Amorphous Solid Dispersion in Cellulose ω-Carboxyalkanoate Matrices
- (2018) Hale Çiğdem Arca et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Implant infections: adhesion, biofilm formation and immune evasion
- (2018) Carla Renata Arciola et al. NATURE REVIEWS MICROBIOLOGY
- Targeted Chemo-Photothermal Therapy: A Nanomedicine Approximation to Selective Melanoma Treatment
- (2018) Gonzalo Villaverde et al. PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
- Iron Oxide Nanoparticles Supported on Mesoporous MCM-41 for Efficient Adsorption of Hazardous β-Lactamic Antibiotics
- (2018) Adriana Barbosa Salviano et al. WATER AIR AND SOIL POLLUTION
- Folic acid-modified mesoporous silica nanoparticles with pH-responsiveness loaded with Amp for an enhanced effect against anti-drug-resistant bacteria by overcoming efflux pump systems
- (2018) Xu Chen et al. Biomaterials Science
- Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms
- (2018) Chun Xu et al. Journal of Materials Chemistry B
- From proof-of-concept material to PEGylated and modularly targeted ultrasound-responsive mesoporous silica nanoparticles
- (2018) Juan L. Paris et al. Journal of Materials Chemistry B
- Mesoporous silica nanoparticles engineered for ultrasound-induced uptake by cancer cells
- (2018) Juan L. Paris et al. Nanoscale
- Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview
- (2018) Alexandra-Cristina Burdușel et al. Nanomaterials
- Suicide-gene transfection of tumor-tropic placental stem cells employing ultrasound-responsive nanoparticles
- (2018) Juan L. Paris et al. Acta Biomaterialia
- Mixed-charge pseudo-zwitterionic mesoporous silica nanoparticles with low-fouling and reduced cell uptake properties
- (2018) Noemí Encinas et al. Acta Biomaterialia
- Molecular Scaffolds as Double-Targeting Agents For the Diagnosis and Treatment of Neuroblastoma
- (2018) Gonzalo Villaverde et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Redox/pH dual-controlled release of chlorhexidine and silver ions from biodegradable mesoporous silica nanoparticles against oral biofilms
- (2018) Meng-meng Lu et al. International Journal of Nanomedicine
- Mesoporous Silica Materials as Drug Delivery: “The Nightmare” of Bacterial Infection
- (2018) Marina Martínez-Carmona et al. Pharmaceutics
- Mesoporous silica nanoparticles carrying multiple antibiotics provide enhanced synergistic effect and improved biocompatibility
- (2018) Zahra Gounani et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Mesoporous silica nanoparticles as a new carrier methodology in the controlled release of the active components in a polypill
- (2017) Antonio L. Doadrio et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Biofilms: Survival and defense strategy for pathogens
- (2017) Ashutosh Kumar et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Thermally Activated Delayed Fluorescence and Aggregation Induced Emission with Through-Space Charge Transfer
- (2017) Hiroyuki Tsujimoto et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Pathogen-Specific Cargo Delivery Platform Based on Mesoporous Silica Nanoparticles
- (2017) Bastian Ruehle et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights
- (2017) María Vallet-Regí et al. MOLECULES
- Broadening the antibacterial spectrum of histidine kinase autophosphorylation inhibitors via the use of ε-poly-L-lysine capped mesoporous silica-based nanoparticles
- (2017) Nadya Velikova et al. Nanomedicine-Nanotechnology Biology and Medicine
- A novel visible light responsive nanosystem for cancer treatment
- (2017) M. Martínez-Carmona et al. Nanoscale
- Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam - mediated activity against Streptococcus pneumoniae biofilms
- (2017) Raymond N. Allan et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Self-immolative polymers as novel pH-responsive gate keepers for drug delivery
- (2017) M. Gisbert-Garzaran et al. RSC Advances
- Development of arginine based nanocarriers for targeting and treatment of intracellular Salmonella
- (2017) Rajeev J. Mudakavi et al. RSC Advances
- A multifunctional nanoplatform based on mesoporous silica nanoparticles for imaging-guided chemo/photodynamic synergetic therapy
- (2017) Yadan Liu et al. RSC Advances
- Silica-based nanoparticles for therapeutic protein delivery
- (2017) Meihua Yu et al. Journal of Materials Chemistry B
- Antibiotic-loaded, silver core-embedded mesoporous silica nanovehicles as a synergistic antibacterial agent for the treatment of drug-resistant infections
- (2016) Yao Wang et al. BIOMATERIALS
- Synergistic eradication of antibiotic-resistant bacteria based biofilms in vivo using a NIR-sensitive nanoplatform
- (2016) Kai Dong et al. CHEMICAL COMMUNICATIONS
- Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
- (2016) Mahdi Karimi et al. CHEMICAL SOCIETY REVIEWS
- Co-modified MCM-41 as an effective adsorbent for levofloxacin removal from aqueous solution: optimization of process parameters, isotherm, and thermodynamic studies
- (2016) Ting Jin et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Redox-Triggered Release of Moxifloxacin from Mesoporous Silica Nanoparticles Functionalized with Disulfide Snap-Tops Enhances Efficacy Against Pneumonic Tularemia in Mice
- (2016) Bai-Yu Lee et al. Small
- Recent advances in mesoporous silica nanoparticles for antitumor therapy: our contribution
- (2016) Alejandro Baeza et al. Biomaterials Science
- Silica core–shell particles for the dual delivery of gentamicin and rifamycin antibiotics
- (2016) Andrea M. Mebert et al. Journal of Materials Chemistry B
- Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers
- (2016) Shu J. Lam et al. Nature Microbiology
- Polymer-Grafted Mesoporous Silica Nanoparticles as Ultrasound-Responsive Drug Carriers
- (2015) Juan L. Paris et al. ACS Nano
- Antibiotic loaded nanocapsules functionalized with aptamer gates for targeted destruction of pathogens
- (2015) M. Kavruk et al. CHEMICAL COMMUNICATIONS
- Drug release from ordered mesoporous silicas
- (2015) Antonio Doadrio et al. CURRENT PHARMACEUTICAL DESIGN
- Prevalence of Total Hip and Knee Replacement in the United States
- (2015) Hilal Maradit Kremers et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Magnetic-Responsive Release Controlled by Hot Spot Effect
- (2015) Eduardo Guisasola et al. LANGMUIR
- pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice
- (2015) Angela A. Hwang et al. Small
- Targeting bacteria via iminoboronate chemistry of amine-presenting lipids
- (2015) Anupam Bandyopadhyay et al. Nature Communications
- Carbohydrate-Conjugated Hollow Oblate Mesoporous Silica Nanoparticles as Nanoantibiotics to Target Mycobacteria
- (2015) Nanjing Hao et al. Advanced Healthcare Materials
- Trehalose-Conjugated, Photofunctionalized Mesoporous Silica Nanoparticles for Efficient Delivery of Isoniazid into Mycobacteria
- (2015) Juan Zhou et al. ACS Biomaterials-Science & Engineering
- Trehalose-Conjugated, Photofunctionalized Mesoporous Silica Nanoparticles for Efficient Delivery of Isoniazid into Mycobacteria
- (2015) Juan Zhou et al. ACS Biomaterials Science & Engineering
- Facile, One-Pot Synthesis, and Antibacterial Activity of Mesoporous Silica Nanoparticles Decorated with Well-Dispersed Silver Nanoparticles
- (2014) Yue Tian et al. ACS Applied Materials & Interfaces
- Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery
- (2014) Alejandro Baeza et al. Expert Opinion on Drug Delivery
- Eradicating group A streptococcus bacteria and biofilms using functionalised multi-wall carbon nanotubes
- (2014) Nicole Levi-Polyachenko et al. INTERNATIONAL JOURNAL OF HYPERTHERMIA
- Mesoporous Silica Nanoparticles (MCM-41) Coated PEGylated Chitosan as a pH-Responsive Nanocarrier for Triggered Release of Erythromycin
- (2014) Ali Pourjavadi et al. International Journal of Polymeric Materials and Polymeric Biomaterials
- The influence of the crystalline nature of nano-metal oxides on their antibacterial and toxicity properties
- (2014) Ilana Perelshtein et al. Nano Research
- Nanomedicine in the management of microbial infection – Overview and perspectives
- (2014) Xi Zhu et al. Nano Today
- Vancomycin-Modified Mesoporous Silica Nanoparticles for Selective Recognition and Killing of Pathogenic Gram-Positive Bacteria Over Macrophage-Like Cells
- (2013) Guobin Qi et al. ACS Applied Materials & Interfaces
- A review of the biomaterials technologies for infection-resistant surfaces
- (2013) Davide Campoccia et al. BIOMATERIALS
- Enhanced Efficacy and Broadening of Antibacterial Action of Drugs via the Use of Capped Mesoporous Nanoparticles
- (2013) Núria Mas et al. CHEMISTRY-A EUROPEAN JOURNAL
- Silver Nanoparticles in Cancer: Therapeutic Efficacy and Toxicity
- (2013) C. Ong et al. CURRENT MEDICINAL CHEMISTRY
- Recent lessons for the management of bone and joint infections
- (2013) Sheldon L. Kaplan JOURNAL OF INFECTION
- Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency
- (2013) Anna Lesniak et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- General Aspects and Recent Advances on Bacterial Protein Toxins
- (2013) E. Lemichez et al. Cold Spring Harbor Perspectives in Medicine
- Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics
- (2012) Aleksandar F. Radovic-Moreno et al. ACS Nano
- Targeted Intracellular Delivery of Antituberculosis Drugs to Mycobacterium tuberculosis-Infected Macrophages via Functionalized Mesoporous Silica Nanoparticles
- (2012) Daniel L. Clemens et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Functionalized mesoporous silica materials for controlled drug delivery
- (2012) Piaoping Yang et al. CHEMICAL SOCIETY REVIEWS
- Preparation of AgBr@SiO2 core@shell hybrid nanoparticles and their bactericidal activity
- (2012) Yuanyuan Li et al. Materials Science & Engineering C-Materials for Biological Applications
- Inflammatory bone loss: pathogenesis and therapeutic intervention
- (2012) Kurt Redlich et al. NATURE REVIEWS DRUG DISCOVERY
- Structure and functionalization of mesoporous bioceramics for bone tissue regeneration and local drug delivery
- (2012) M. Vallet-Regi et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- “Nanoantibiotics”: A new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era
- (2011) Ae Jung Huh et al. JOURNAL OF CONTROLLED RELEASE
- Medical applications of organic–inorganic hybrid materials within the field of silica-based bioceramics
- (2010) María Vallet-Regí et al. CHEMICAL SOCIETY REVIEWS
- Antibiotic resistance of bacterial biofilms
- (2010) Niels Høiby et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- New developments in ordered mesoporous materials for drug delivery
- (2010) Miguel Manzano et al. JOURNAL OF MATERIALS CHEMISTRY
- Surface Electrochemistry of Mesoporous Silicas as a Key Factor in the Design of Tailored Delivery Devices
- (2010) Alejandra Nieto et al. LANGMUIR
- A rational explanation of the vancomycin release from SBA-15 and its derivative by molecular modelling
- (2010) Antonio L. Doadrio et al. MICROPOROUS AND MESOPOROUS MATERIALS
- Antimicrobial Activity of Silver Nanocrystals Encapsulated in Mesoporous Silica Nanoparticles
- (2009) Monty Liong et al. ADVANCED MATERIALS
- Bacillus subtilis spreads by surfing on waves of surfactant
- (2009) T. E. Angelini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells
- (2008) P. V. AshaRani et al. ACS Nano
- L-Trp adsorption into silica mesoporous materials to promote bone formation
- (2008) Francisco Balas et al. Acta Biomaterialia
- Using Aptamer–Nanoparticle Conjugates for Cancer Cells Detection
- (2008) Xiaolan Chen et al. Journal of Biomedical Nanotechnology
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