Hypoxia inducible lncRNA-CBSLR modulates ferroptosis through m6A-YTHDF2-dependent modulation of CBS in gastric cancer

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability

(2021) Pengpeng Zhu et al.   ONCOGENE

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Broadening horizons: the role of ferroptosis in cancer

(2021) Xin Chen et al.   Nature Reviews Clinical Oncology

Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs

(2020) Yanwei Su et al.   CANCER LETTERS

The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

(2020) Guang Lei et al.   CELL RESEARCH

Hypoxia induced LUCAT1/PTBP1 axis modulates cancer cell viability and chemotherapy response

(2020) Lin Huan et al.   Molecular Cancer

Integrating tumor hypoxic stress in novel and more adaptable strategies for cancer immunotherapy

(2020) Raefa Abou Khouzam et al.   SEMINARS IN CANCER BIOLOGY

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

(2020) Xiaoguang Liu et al.   NATURE CELL BIOLOGY

HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer

(2020) Ellen C. de Heer et al.   JOURNAL OF CLINICAL INVESTIGATION

Gastric cancer

(2020) Elizabeth C Smyth et al.   LANCET

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

(2020) Pranavi Koppula et al.   Protein & Cell

The Metabolic Underpinnings of Ferroptosis

(2020) Jiashuo Zheng et al.   Cell Metabolism

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular landmarks of tumor hypoxia across cancer types

(2019) Vinayak Bhandari et al.   NATURE GENETICS

WHISTLE: a high-accuracy map of the human N6-methyladenosine (m6A) epitranscriptome predicted using a machine learning approach

(2019) Kunqi Chen et al.   NUCLEIC ACIDS RESEARCH

The Critical Role of RNA m6A Methylation in Cancer

(2019) Qing Lan et al.   CANCER RESEARCH

Multifunctional nanoplatform for photoacoustic imaging-guided combined therapy enhanced by CO induced ferroptosis

(2019) Xianxian Yao et al.   BIOMATERIALS

Clockophagy is a novel selective autophagy process favoring ferroptosis

(2019) Minghua Yang et al.   Science Advances

Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia

(2019) Zan Li et al.   Redox Biology

YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma

(2019) Jiajie Hou et al.   Molecular Cancer

Cystathionine β-Synthase in Physiology and Cancer

(2018) Haoran Zhu et al.   Biomed Research International

lncRNA GCAWKR Promotes Gastric Cancer Development by Scaffolding the Chromatin Modification Factors WDR5 and KAT2A

(2018) Mingzhe Ma et al.   MOLECULAR THERAPY

POSTAR2: deciphering the post-transcriptional regulatory logics

(2018) Yumin Zhu et al.   NUCLEIC ACIDS RESEARCH

A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis

(2018) Li Wang et al.   Cell Death & Disease

N 6 -methyladenosine is required for the hypoxic stabilization of specific mRNAs

(2017) Nate J. Fry et al.   RNA

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

(2017) Jing-Wen Shih et al.   Nature Communications

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

(2016) Chuanzhao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

(2015) M Hayano et al.   CELL DEATH AND DIFFERENTIATION

Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine

(2014) Tingting Zhu et al.   CELL RESEARCH

Decreased Expression of Cystathionine β-Synthase Promotes Glioma Tumorigenesis

(2014) Naoharu Takano et al.   MOLECULAR CANCER RESEARCH

RBPmap: a web server for mapping binding sites of RNA-binding proteins

(2014) Inbal Paz et al.   NUCLEIC ACIDS RESEARCH

Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway

(2014) Takehiro Yamamoto et al.   Nature Communications

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

(2013) Jean-Michel Fustin et al.   CELL

Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

(2013) Fan Yang et al.   MOLECULAR CELL

Tumor-derived hydrogen sulfide, produced by cystathionine- -synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

(2013) C. Szabo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequent Epigenetic Silencing of the Folate-Metabolising Gene Cystathionine-Beta-Synthase in Gastrointestinal Cancer

(2012) Hong Zhao et al.   PLoS One

Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase

(2010) Takehiro Yamamoto et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION