YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma
出版年份 2019 全文链接
标题
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma
作者
关键词
-
出版物
Molecular Cancer
Volume 18, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-18
DOI
10.1186/s12943-019-1082-3
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network
- (2019) Maosheng Cheng et al. ONCOGENE
- Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia
- (2019) Jasmin Paris et al. Cell Stem Cell
- RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
- (2019) Xinyao Lin et al. Nature Communications
- R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling
- (2018) Rui Su et al. CELL
- METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification
- (2018) Hengyou Weng et al. Cell Stem Cell
- RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
- (2018) Mengnuo Chen et al. HEPATOLOGY
- Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma
- (2018) Kevin D. Courtney et al. JOURNAL OF CLINICAL ONCOLOGY
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- Notch signaling promotes a HIF2α-driven hypoxic response in multiple tumor cell types
- (2018) Anders P. Mutvei et al. ONCOGENE
- Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion
- (2018) Zhenrui Li et al. CELL RESEARCH
- mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis
- (2018) Junho Choe et al. NATURE
- m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
- (2018) Jun Liu et al. NATURE CELL BIOLOGY
- Molecular therapies and precision medicine for hepatocellular carcinoma
- (2018) Josep M. Llovet et al. Nature Reviews Clinical Oncology
- YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA in hepatocellular carcinoma
- (2018) Li Zhong et al. CANCER LETTERS
- Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
- (2017) Isaia Barbieri et al. NATURE
- N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
- (2017) Raghu R Edupuganti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- N 6 -methyladenosine is required for the hypoxic stabilization of specific mRNAs
- (2017) Nate J. Fry et al. RNA
- Reprogramming of the Tumor in the Hypoxic Niche: The Emerging Concept and Associated Therapeutic Strategies
- (2017) Guan-Zhong Qiu et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Increasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals
- (2017) Junjie Xu et al. Cell Death & Disease
- N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
- (2017) Raghu R Edupuganti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
- (2017) Qi Cui et al. Cell Reports
- METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing
- (2016) Jin-zhao Ma et al. HEPATOLOGY
- Tumour hypoxia causes DNA hypermethylation by reducing TET activity
- (2016) Bernard Thienpont et al. NATURE
- Targeting renal cell carcinoma with a HIF-2 antagonist
- (2016) Wenfang Chen et al. NATURE
- Post-transcriptional gene regulation by mRNA modifications
- (2016) Boxuan Simen Zhao et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
- (2016) Chuanzhao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxic control of metastasis
- (2016) E. B. Rankin et al. SCIENCE
- Hypoxia Induces Production of L-2-Hydroxyglutarate
- (2015) Andrew M. Intlekofer et al. Cell Metabolism
- A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis
- (2015) Elvin Wagenblast et al. NATURE
- A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma
- (2014) Ji-hang Yuan et al. CANCER CELL
- Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis
- (2014) Manuel Valiente et al. CELL
- Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine
- (2014) Tingting Zhu et al. CELL RESEARCH
- Hypoxia inducible factors in liver disease and hepatocellular carcinoma: Current understanding and future directions
- (2014) Garrick K. Wilson et al. JOURNAL OF HEPATOLOGY
- Internal mRNA Methylation Finally Finds Functions
- (2014) T. W. Nilsen SCIENCE
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- Vascular Normalization as a Therapeutic Strategy for Malignant and Nonmalignant Disease
- (2013) S. Goel et al. Cold Spring Harbor Perspectives in Medicine
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- Passing the baton: the HIF switch
- (2012) Mei Yee Koh et al. TRENDS IN BIOCHEMICAL SCIENCES
- The Hypoxia-Associated Factor Switches Cells from HIF-1 - to HIF-2 -Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
- (2011) M. Y. Koh et al. CANCER RESEARCH
- Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
- (2010) F M Buffa et al. BRITISH JOURNAL OF CANCER
- gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
- (2009) Julia Bollrath et al. CANCER CELL
- Plasminogen Activator Inhibitor-1 Protects Endothelial Cells from FasL-Mediated Apoptosis
- (2008) Khalid Bajou et al. CANCER CELL
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