Troglitazone-Induced PRODH/POX-Dependent Apoptosis Occurs in the Absence of Estradiol or ERβ in ER-Negative Breast Cancer Cells

Molecular Targeting of RRM2, NF-κB, and Mutant TP53 for the Treatment of Triple-Negative Breast Cancer

(2021) Elizabeth A. Wilson et al.   MOLECULAR CANCER THERAPEUTICS

Endoxifen, an Estrogen Receptor Targeted Therapy: from Bench to Bedside

(2021) Swaathi Jayaraman et al.   ENDOCRINOLOGY

Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy

(2020) Thi Yen Ly Huynh et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Current Understanding of the Emerging Role of Prolidase in Cellular Metabolism

(2020) Magdalena Misiura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development of an LC-MS Targeted Metabolomics Methodology to Study Proline Metabolism in Mammalian Cell Cultures

(2020) Agnieszka Klupczynska et al.   MOLECULES

Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis

(2018) Yihong Zhang et al.   CELL DEATH AND DIFFERENTIATION

The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity

(2018) Saghar Yousefnia et al.   GENE

Troglitazone Inhibits Matrix Metalloproteinase-9 Expression and Invasion of Breast Cancer Cell through a Peroxisome Proliferator-Activated Receptor γ-Dependent Mechanism

(2018) On-Yu Hong et al.   Journal of Breast Cancer

Proline oxidase silencing induces proline-dependent pro-survival pathways in MCF-7 cells

(2018) Ilona Zareba et al.   Oncotarget

Targeting Peroxisome Proliferator-Activated Receptor γ to Increase Estrogen-Induced Apoptosis in Estrogen-Deprived Breast Cancer Cells

(2018) Ping Fan et al.   MOLECULAR CANCER THERAPEUTICS

The role of mitochondria in cardiac development and protection

(2017) Jaakko L. Pohjoismäki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Estrogen Receptor-β Modulation of the ERα-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast Cancer

(2017) Wenwen Lu et al.   Hormones & Cancer

Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses

(2017) James M. Phang   ANTIOXIDANTS & REDOX SIGNALING

Protein Profiles Associated with Anoikis Resistance of Metastatic MDA-MB-231 Breast Cancer Cells

(2016) Chareeporn Akekawatchai et al.   Asian Pacific Journal of Cancer Prevention

Prolidase-proline dehydrogenase/proline oxidase-collagen biosynthesis axis as a potential interface of apoptosis/autophagy

(2016) Ilona Zareba et al.   BIOFACTORS

Fatty acids, eicosanoids and PPAR gamma

(2016) Rachel Marion-Letellier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PPARγ signaling and emerging opportunities for improved therapeutics

(2016) Shuibang Wang et al.   PHARMACOLOGICAL RESEARCH

Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism

(2015) C A Sartorius et al.   ONCOGENE

In vitro human cell line models to predict clinical response to anticancer drugs

(2015) Nifang Niu et al.   PHARMACOGENOMICS

An Ideal PPAR Response Element Bound to and Activated by PPARα

(2015) John Tzeng et al.   PLoS One

Metastatic potential in MDA-MB-231 human breast cancer cells is inhibited by proton beam irradiation via the Akt/nuclear factor-κB signaling pathway

(2014) KYU-SHIK LEE et al.   Molecular Medicine Reports

Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review

(2014) Bogna Grygiel-Górniak   Nutrition Journal

Estrogen receptor α mediates proliferation of breast cancer MCF-7 cells via a p21/PCNA/E2F1-dependent pathway

(2013) Xing-Hua Liao et al.   FEBS Journal

The effect of estrogen on prolidase-dependent regulation of HIF-1α expression in breast cancer cells

(2013) Arkadiusz Surazynski et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Proline dehydrogenase (oxidase) in cancer

(2012) Wei Liu et al.   BIOFACTORS

Synthesis of new troglitazone derivatives: Anti-proliferative activity in breast cancer cell lines and preliminary toxicological study

(2012) Stéphane Salamone et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Role for Estrogen Receptor-α and Estrogen Receptor-β in Collagen Biosynthesis in Mouse Skin

(2012) Margaret Markiewicz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The development, application and limitations of breast cancer cell lines to study tamoxifen and aromatase inhibitor resistance

(2012) Cynthie Wong et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen receptor prevents p53-dependent apoptosis in breast cancer

(2012) S. T. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New troglitazone derivatives devoid of PPARγ agonist activity display an increased antiproliferative effect in both hormone-dependent and hormone-independent breast cancer cell lines

(2010) Christelle Colin et al.   BREAST CANCER RESEARCH AND TREATMENT

Estrogen receptor beta participate in the regulation of metabolizm of extracellular matrix in estrogen alpha negative breast cancer.

(2010) Monika Leśniewska et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation

(2010) S. D. Konduri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells

(2009) Beata Kociecka et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PPARγ activation induces autophagy in breast cancer cells

(2009) Jie Zhou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Estrogen-dependent Regulation of PPAR-γ Signaling on Collagen Biosynthesis in Adenocarcinoma Endometrial Cells

(2009) A. SURAZYNSKI et al.   NEOPLASMA

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL