Genome-editing prodrug: Targeted delivery and conditional stabilization of CRISPR-Cas9 for precision therapy of inflammatory disease
出版年份 2021 全文链接
标题
Genome-editing prodrug: Targeted delivery and conditional stabilization of CRISPR-Cas9 for precision therapy of inflammatory disease
作者
关键词
-
出版物
Science Advances
Volume 7, Issue 50, Pages -
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-12-09
DOI
10.1126/sciadv.abj0624
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Plasmonic-Fluorescent Janus Ag/Ag2S Nanoparticles for In Situ H2O2-Activated NIR-II Fluorescence Imaging
- (2021) Xuan Zhang et al. NANO LETTERS
- Microneedle-assisted genome editing: A transdermal strategy of targeting NLRP3 by CRISPR-Cas9 for synergistic therapy of inflammatory skin disorders
- (2021) Tao Wan et al. Science Advances
- The promise and challenge of therapeutic genome editing
- (2020) Jennifer A. Doudna NATURE
- Near-infrared optogenetic engineering of photothermal nanoCRISPR for programmable genome editing
- (2020) Xiaohong Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell Engineering with Functional Poly(oxanorbornene) Block Copolymers
- (2020) Derek C. Church et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Homologous-targeting biomimetic nanoparticles for photothermal therapy and Nrf2-siRNA amplified photodynamic therapy against oral tongue squamous cell carcinoma
- (2020) Shurui Shi et al. CHEMICAL ENGINEERING JOURNAL
- Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
- (2020) Qiang Cheng et al. Nature Nanotechnology
- Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
- (2020) Cheng Gao et al. Nature Communications
- Homotypic Targeting Delivery of siRNA with Artificial Cancer Cells
- (2020) Lingmin Zhang et al. Advanced Healthcare Materials
- Engineering a far-red light–activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors
- (2020) Yuanhuan Yu et al. Science Advances
- Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium
- (2019) Asha Kumari Patel et al. ADVANCED MATERIALS
- CRISPResso2 provides accurate and rapid genome editing sequence analysis
- (2019) Kendell Clement et al. NATURE BIOTECHNOLOGY
- Nanoscale ATP-Responsive Zeolitic Imidazole Framework-90 as a General Platform for Cytosolic Protein Delivery and Genome Editing
- (2019) Xiaoti Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9
- (2019) Amit Choudhary et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles
- (2019) Ji Liu et al. ADVANCED MATERIALS
- Bioresponsive Protein Complex of aPD1 and aCD47 Antibodies for Enhanced Immunotherapy
- (2019) Qian Chen et al. NANO LETTERS
- Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD
- (2019) Yi Rang Na et al. Nature Reviews Gastroenterology & Hepatology
- Highly branched poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells
- (2019) Shuai Liu et al. Nature Communications
- Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis
- (2019) Yonghyun Lee et al. NATURE MATERIALS
- Rational designs of in vivo CRISPR-Cas delivery systems
- (2019) Cong-Fei Xu et al. ADVANCED DRUG DELIVERY REVIEWS
- Development of Cationic Quaternary Ammonium Sulfonamide Amino Lipids for Nucleic Acid Delivery
- (2018) Jason B. Miller et al. ACS Applied Materials & Interfaces
- Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-Assisted Polymeric Nanoparticles
- (2018) Ying-Li Luo et al. ACS Nano
- Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
- (2018) Guiyang Zhang et al. Nature Communications
- Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis
- (2018) Qiangzhe Zhang et al. Nature Nanotechnology
- Green Tea Catechin Dramatically Promotes RNAi Mediated by Low-Molecular-Weight Polymers
- (2018) Wanwan Shen et al. ACS Central Science
- Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases
- (2018) Congfei Xu et al. Nature Communications
- Hypoxia-sensitive pathways in intestinal inflammation
- (2017) Eric Brown et al. JOURNAL OF PHYSIOLOGY-LONDON
- Bacterial infection imaging with [18F]fluoropropyl-trimethoprim
- (2017) Mark A. Sellmyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disabling Cas9 by an anti-CRISPR DNA mimic
- (2017) Jiyung Shin et al. Science Advances
- Substrate Ubiquitination Controls the Unfolding Ability of the Proteasome
- (2016) Eden L. Reichard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
- (2016) Yi-Nan Zhang et al. JOURNAL OF CONTROLLED RELEASE
- CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
- (2016) Daniel P. Dever et al. NATURE
- Multidimensional chemical control of CRISPR–Cas9
- (2016) Basudeb Maji et al. Nature Chemical Biology
- A multifunctional AAV–CRISPR–Cas9 and its host response
- (2016) Wei Leong Chew et al. NATURE METHODS
- Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases
- (2016) Shengdar Q. Tsai et al. NATURE REVIEWS GENETICS
- The transition from linear to highly branched poly( -amino ester)s: Branching matters for gene delivery
- (2016) D. Zhou et al. Science Advances
- Principles of nanoparticle design for overcoming biological barriers to drug delivery
- (2015) Elvin Blanco et al. NATURE BIOTECHNOLOGY
- A split-Cas9 architecture for inducible genome editing and transcription modulation
- (2015) Bernd Zetsche et al. NATURE BIOTECHNOLOGY
- Small molecule–triggered Cas9 protein with improved genome-editing specificity
- (2015) Kevin M Davis et al. Nature Chemical Biology
- The chemotaxis of M1 and M2 macrophages is regulated by different chemokines
- (2014) Wenjuan Xuan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Enzyme-responsive nanomaterials for controlled drug delivery
- (2014) Quanyin Hu et al. Nanoscale
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA
- (2014) C. Long et al. SCIENCE
- pH-Responsive Micro- and Nanocarrier Systems
- (2013) Sabrina Nowag et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair
- (2012) S. Willenborg et al. BLOOD
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now