Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis

Immunomodulatory nanogels overcome restricted immunity in a murine model of gut microbiome–mediated metabolic syndrome

(2019) Matthew J. Mosquera et al.   Science Advances

Bilirubin Nanoparticle-Assisted Delivery of a Small Molecule-Drug Conjugate for Targeted Cancer Therapy

(2018) Soyoung Lee et al.   BIOMACROMOLECULES

Inorganic nanoparticles and the microbiome

(2018) Kunyu Qiu et al.   Nano Research

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

(2018) Chi Ma et al.   SCIENCE

Intestinal barriers protect against disease

(2018) Sandra Citi   SCIENCE

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

Chlorogenic Acid Ameliorates Experimental Colitis by Promoting Growth of Akkermansia in Mice

(2017) Zhan Zhang et al.   Nutrients

Gut Dysbiosis and Neurobehavioral Alterations in Rats Exposed to Silver Nanoparticles

(2017) Angela B. Javurek et al.   Scientific Reports

Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

(2017) Patrice D. Cani et al.   Frontiers in Microbiology

Dynamics of the human gut microbiome in inflammatory bowel disease

(2017) Jonas Halfvarson et al.   Nature Microbiology

Bilirubin Nanoparticles as a Nanomedicine for Anti-inflammation Therapy

(2016) Yonghyun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Human Intestinal Microbiome in Health and Disease

(2016) Susan V. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

New frontiers in nanotoxicology: Gut microbiota/microbiome-mediated effects of engineered nanomaterials

(2016) Antonio Pietroiusti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation

(2016) Bo Xiao et al.   Theranostics

Fecal Microbiota Transplantation Eliminates Clostridium difficile in a Murine Model of Relapsing Disease

(2015) Anna M. Seekatz et al.   INFECTION AND IMMUNITY

An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease

(2015) Sufeng Zhang et al.   Science Translational Medicine

High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation

(2015) Jamie E. Rayahin et al.   ACS Biomaterials-Science & Engineering

High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation

(2015) Jamie E. Rayahin et al.   ACS Biomaterials Science & Engineering

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Hyaluronan, a Crucial Regulator of Inflammation

(2014) Aaron C. Petrey et al.   Frontiers in Immunology

Drug delivery strategies in the therapy of inflammatory bowel disease

(2013) Christian Lautenschläger et al.   ADVANCED DRUG DELIVERY REVIEWS

Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform

(2013) James J. Kozich et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IL-10 modulates DSS-induced colitis through a macrophage–ROS–NO axis

(2013) B Li et al.   Mucosal Immunology

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific-sized Hyaluronan Fragments Promote Expression of Human β-Defensin 2 in Intestinal Epithelium

(2012) David R. Hill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Randomised clinical trial: the effectiveness of Lactobacillus reuteri ATCC 55730 rectal enema in children with active distal ulcerative colitis

(2011) S. Oliva et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

(2010) Chin Wen Png et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Adverse effects of biologics used for treating IBD

(2010) Andreas Stallmach et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities

(2009) P. D. Schloss et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Regulation of Colonic Epithelial Repair in Mice by Toll-Like Receptors and Hyaluronic Acid

(2009) Ling Zheng et al.   GASTROENTEROLOGY

World Gastroenterology Organization Practice Guidelines for the Diagnosis and Management of IBD in 2010

(2009) Charles N. Bernstein et al.   INFLAMMATORY BOWEL DISEASES

Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells

(2009) Paul L. Bollyky et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Bilirubin and glutathione have complementary antioxidant and cytoprotective roles

(2009) T. W. Sedlak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA