标题
TREM-2 is a sensor and activator of T cell response in SARS-CoV-2 infection
作者
关键词
-
出版物
Science Advances
Volume 7, Issue 50, Pages -
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-12-09
DOI
10.1126/sciadv.abi6802
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
- (2020) Zunyou Wu et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pathological findings of COVID-19 associated with acute respiratory distress syndrome
- (2020) Zhe Xu et al. Lancet Respiratory Medicine
- SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
- (2020) Carly G.K. Ziegler et al. CELL
- Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
- (2020) Bo Shen et al. CELL
- Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
- (2020) Alba Grifoni et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure
- (2020) Evangelos J. Giamarellos-Bourboulis et al. Cell Host & Microbe
- Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals
- (2020) Ling Ni et al. IMMUNITY
- Virological assessment of hospitalized patients with COVID-2019
- (2020) Roman Wölfel et al. NATURE
- TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling
- (2020) Zhenbang Zhu et al. PLoS Pathogens
- Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2
- (2020) James Brett Case et al. Cell Host & Microbe
- Dysregulated adaptive immune response contributes to severe COVID-19
- (2020) Kuai Yu et al. CELL RESEARCH
- Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome
- (2020) Daniela Weiskopf et al. Science Immunology
- Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
- (2020) Takuya Sekine et al. CELL
- Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
- (2020) Jin Wei et al. CELL
- Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
- (2020) Yanchun Peng et al. NATURE IMMUNOLOGY
- TMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities
- (2020) Zhaoji Liu et al. Cell Death & Disease
- SARS-CoV-2–specific T cells are rapidly expanded for therapeutic use and target conserved regions of the membrane protein
- (2020) Michael D. Keller et al. BLOOD
- Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19
- (2020) Qirui Guo et al. Cell Host & Microbe
- Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
- (2019) Antonio Boza-Serrano et al. ACTA NEUROPATHOLOGICA
- Membrane protein of HCoV-NL63 is responsible for interaction with the adhesion receptor.
- (2019) Antonina Naskalska et al. JOURNAL OF VIROLOGY
- Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage
- (2018) Maria J Perugorria et al. GUT
- TREM2 in Neurodegenerative Diseases
- (2017) Taylor R. Jay et al. Molecular Neurodegeneration
- TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
- (2017) Cheryl E. G. Leyns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis
- (2017) Lindsay Kosack et al. Scientific Reports
- The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism
- (2016) Yi Wang et al. mBio
- Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis
- (2016) Tassili A. F. Weehuizen et al. PLoS Neglected Tropical Diseases
- Innate Immune Pattern Recognition: A Cell Biological Perspective
- (2015) Sky W. Brubaker et al. Annual Review of Immunology
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM2 sustains microglial expansion during aging and response to demyelination
- (2015) Pietro Luigi Poliani et al. JOURNAL OF CLINICAL INVESTIGATION
- TREM-2 promotes macrophage survival and lung disease after respiratory viral infection
- (2015) Kangyun Wu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Soluble and cell-associated triggering receptor expressed on myeloid cells-1 and -2 in patients with pulmonary tuberculosis
- (2015) Arie J. Hoogendijk et al. JOURNAL OF INFECTION
- T cell receptor dwell times control the kinase activity of Zap70
- (2015) Christian Klammt et al. NATURE IMMUNOLOGY
- T Cell Responses to Whole SARS Coronavirus in Humans
- (2014) C. K.-f. Li et al. JOURNAL OF IMMUNOLOGY
- Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage
- (2013) Patrick Wunderlich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toll-like receptor regulation of effector T lymphocyte function
- (2013) Joseph M. Reynolds et al. TRENDS IN IMMUNOLOGY
- Bacterial Sensor Triggering Receptor Expressed on Myeloid Cells-2 Regulates the Mucosal Inflammatory Response
- (2012) Carmen Correale et al. GASTROENTEROLOGY
- Specific lipid recognition is a general feature of CD300 and TREM molecules
- (2011) John P. Cannon et al. IMMUNOGENETICS
- Differentiation of Effector CD4 T Cell Populations
- (2010) Jinfang Zhu et al. Annual Review of Immunology
- Toll-like Receptor 2 Signaling in CD4+ T Lymphocytes Promotes T Helper 17 Responses and Regulates the Pathogenesis of Autoimmune Disease
- (2010) Joseph M. Reynolds et al. IMMUNITY
- The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Acts as a Dominant Immunogen Revealed by a Clustering Region of Novel Functionally and Structurally Defined Cytotoxic T‐Lymphocyte Epitopes
- (2010) Jun Liu et al. JOURNAL OF INFECTIOUS DISEASES
- T Cell Responses Are Required for Protection from Clinical Disease and for Virus Clearance in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice
- (2010) J. Zhao et al. JOURNAL OF VIROLOGY
- Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages
- (2009) Andrew A. Wilson et al. JOURNAL OF CLINICAL INVESTIGATION
- The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor
- (2009) Luisa Stefano et al. JOURNAL OF NEUROCHEMISTRY
- TREM-2 binds to lipooligosaccharides of Neisseria gonorrhoeae and is expressed on reproductive tract epithelial cells
- (2008) D N Quan et al. Mucosal Immunology
- Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses
- (2008) M. Hashiguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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