Combined Oral Contraceptives and Venous Thromboembolism: Review and Perspective to Mitigate the Risk

Prospective controlled cohort study on the safety of a monophasic oral contraceptive containing nomegestrol acetate (2.5mg) and 17β-oestradiol (1.5mg) (PRO-E2 study): risk of venous and arterial thromboembolism

(2021) Suzanne Reed et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

The joint effect of genetic risk factors and different types of combined oral contraceptives on venous thrombosis risk

(2020) Deeksha Khialani et al.   BRITISH JOURNAL OF HAEMATOLOGY

Estetrol (E4): the new estrogenic component of combined oral contraceptives

(2020) Giovanni Grandi et al.   Expert Review of Clinical Pharmacology

Oral contraceptive generations – Time to stop using a marketing myth to define nomenclature

(2020) Mitchell D. Creinin et al.   CONTRACEPTION

Evaluation of the effect of a new oral contraceptive containing estetrol and drospirenone on hemostasis parameters

(2020) Jonathan Douxfils et al.   CONTRACEPTION

Oral Contraceptives and Venous Thromboembolism: Focus on Testing that May Enable Prediction and Assessment of the Risk

(2020) Jonathan Douxfils et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Letter to the Editors-in-Chief in response to the article of Abou-Ismail, et al. entitled “Estrogen and thrombosis: A bench to bedside review” (Thrombosis Research 192 (2020) 40–51)

(2020) Laure Morimont et al.   THROMBOSIS RESEARCH

Validation and standardization of the ETP-based activated protein C resistance test for the clinical investigation of steroid contraceptives in women: an unmet clinical and regulatory need

(2019) Jonathan Douxfils et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Could rs4379368 be a genetic marker for North Indian migraine patients with aura?: Preliminary evidence by a replication study

(2019) Sukhvinder Kaur et al.   NEUROSCIENCE LETTERS

Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis

(2018) Marie-Cécile Valéra et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Type of Combined Contraceptives, Factor V Leiden Mutation and Risk of Venous Thromboembolism

(2018) Justine Hugon-Rodin et al.   THROMBOSIS AND HAEMOSTASIS

Estetrol combined with drospirenone: an oral contraceptive with high acceptability, user satisfaction, well-being and favourable body weight control

(2017) Dan Apter et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

(2017) Jean-Francois Arnal et al.   PHYSIOLOGICAL REVIEWS

Risk prediction of developing venous thrombosis in combined oral contraceptive users

(2017) Aaron McDaid et al.   PLoS One

Progestin-only contraception and thromboembolism: A systematic review

(2016) Naomi K. Tepper et al.   CONTRACEPTION

Bleeding pattern and cycle control with estetrol-containing combined oral contraceptives: results from a phase II, randomised, dose-finding study (FIESTA)

(2016) Dan Apter et al.   CONTRACEPTION

Impact of estrogen type on cardiovascular safety of combined oral contraceptives

(2016) Jürgen Dinger et al.   CONTRACEPTION

About Pill Protect®

(2016) J Michaud et al.   SWISS MEDICAL WEEKLY

Risk factors for venous thromboembolism in women under combined oral contraceptive

(2016) Agathe Henneuse et al.   THROMBOSIS AND HAEMOSTASIS

Classic thrombophilic gene variants

(2015) Massimo Franchini et al.   THROMBOSIS AND HAEMOSTASIS

Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms

(2015) Céline Gérard et al.   Oncotarget

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor   modulation, uncoupling nuclear and membrane activation

(2014) A. Abot et al.   EMBO Molecular Medicine

Current knowledge on the genetics of incident venous thrombosis

(2013) P.-E. Morange et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hemostatic Effects of a Novel Estradiol-Based Oral Contraceptive

(2013) Christine Klipping et al.   Drugs in research & development

Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol compared with one containing levonorgestrel and ethinylestradiol on haemostasis, lipids and carbohydrate metabolism

(2012) Ulla M. Ågren et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest

(2012) Franca Fruzzetti et al.   GYNECOLOGICAL ENDOCRINOLOGY

Sex hormone-binding globulin levels are not causally related to venous thrombosis risk in women not using hormonal contraceptives

(2012) B.H. STEGEMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Sex hormone-binding globulin as a marker for the thrombotic risk of hormonal contraceptives

(2012) M. RAPS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The pharmacology of nomegestrol acetate

(2012) Xiangyan Ruan et al.   MATURITAS

Progestin-only contraception and venous thromboembolism

(2012) M.A. Blanco-Molina et al.   THROMBOSIS RESEARCH

Clinical and biological factors that contribute to thrombin generation in prothrombin G20210A carriers: A case–control study in a single Thrombophilia Center

(2012) Ana Marco et al.   THROMBOSIS RESEARCH

KNG1 Ile581Thr and susceptibility to venous thrombosis

(2011) P.-E. Morange et al.   BLOOD

Metabolic and Haemostatic Effects of Estradiol Valerate/Dienogest, a Novel Oral Contraceptive

(2011) Wolfgang Junge et al.   CLINICAL DRUG INVESTIGATION

Estradiol Valerate/Dienogest: A Novel Combined Oral Contraceptive

(2011) Laura M. Borgelt et al.   CLINICAL THERAPEUTICS

Haemostatic effects of a new combined oral contraceptive, nomegestrol acetate/17β-estradiol, compared with those of levonorgestrel/ethinyl estradiol

(2011) Martine Alhenc-Gelas et al.   THROMBOSIS AND HAEMOSTASIS

Epidemiology of the contraceptive pill and venous thromboembolism

(2011) Philip C. Hannaford   THROMBOSIS RESEARCH

In prothrombin G20210A carriers the genetic mutation and the history of Venous Thrombosis contribute both to thrombin generation independently of factor II plasma levels

(2010) G. Lavigne-Lissalde et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Elevated factor VIII enhances thrombin generation in the presence of factor VIII-deficiency, factor XI-deficiency or fondaparinux

(2010) Fania Szlam et al.   THROMBOSIS RESEARCH

Androgen Receptor Inhibits Estrogen Receptor-  Activity and Is Prognostic in Breast Cancer

(2009) A. A. Peters et al.   CANCER RESEARCH

Bleeding pattern and cycle control with an estradiol-based oral contraceptive: a seven-cycle, randomized comparative trial of estradiol valerate/dienogest and ethinyl estradiol/levonorgestrel

(2009) Hans-Joachim Ahrendt et al.   CONTRACEPTION

Review of clinical experience with estradiol in combined oral contraceptives

(2009) Franca Fruzzetti et al.   CONTRACEPTION

Pharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogest

(2009) Susan Zeun et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

APC resistance: biological basis and acquired influences

(2009) E. CASTOLDI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Estetrol review: profile and potential clinical applications

(2008) H. J. T. Coelingh Bennink et al.   CLIMACTERIC

Estetrol: A unique steroid in human pregnancy

(2008) Christian F. Holinka et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Reprint of Pharmacological profile of progestins

(2008) Regine Sitruk-Ware   MATURITAS

Influence of coagulation factors and tissue factor concentration on the thrombin generation test in plasma

(2008) Brigitte Pan-Petesch et al.   THROMBOSIS AND HAEMOSTASIS