Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook

(2017) Jie Yao   JOURNAL OF MOLECULAR BIOLOGY

Histone H3 phosphorylation, immediate-early gene expression, and the nucleosomal response: a historical perspective1This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.

(2017) Shannon Healy et al.   Biochemistry and Cell Biology

CTCF-mediated chromatin loops enclose inducible gene regulatory domains

(2016) Martin Oti et al.   BMC GENOMICS

Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions

(2016) Erin E. Swinstead et al.   CELL

Enhancer Control of Transcriptional Bursting

(2016) Takashi Fukaya et al.   CELL

Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors

(2016) D. Vareslija et al.   CLINICAL CANCER RESEARCH

Pioneer transcription factors, chromatin dynamics, and cell fate control

(2016) Kenneth S Zaret et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Role of ERα in the Effect of Estradiol on Cancellous and Cortical Femoral Bone in Growing Female Mice

(2016) A. Vinel et al.   ENDOCRINOLOGY

The first decade of estrogen receptor cistromics in breast cancer

(2016) Koen D Flach et al.   JOURNAL OF ENDOCRINOLOGY

Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance

(2016) L. Malorni et al.   MOLECULAR CANCER RESEARCH

Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping

(2016) Caroline R. Bartman et al.   MOLECULAR CELL

Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment

(2016) Gaëlle Palierne et al.   MOLECULAR ENDOCRINOLOGY

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9

(2016) Gozde Korkmaz et al.   NATURE BIOTECHNOLOGY

OCT-4: a novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells

(2016) S Bhatt et al.   ONCOGENE

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

(2016) Zeynep Madak-Erdogan et al.   Science Signaling

The role of membrane ERα signaling in bone and other major estrogen responsive tissues

(2016) K. L. Gustafsson et al.   Scientific Reports

On the way of revealing coactivator complexes cross-talk during transcriptional activation

(2016) Aleksey N. Krasnov et al.   Cell and Bioscience

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

(2016) Zeynep Madak-Erdogan et al.   Science Signaling

Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease

(2016) Anne K. Ludwig et al.   Frontiers in Genetics

Differences in angiotensin (1–7) between men and women

(2015) Jennifer C. Sullivan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus

(2015) Yea Woon Kim et al.   BIOSCIENCE REPORTS

Adjuvant endocrine therapy for early breast cancer: a systematic review of the evidence for the 2014 Cancer Care Ontario systemic therapy guideline

(2015) O.C. Freedman et al.   Current Oncology

The interplay of histone modifications - writers that read

(2015) T. Zhang et al.   EMBO REPORTS

ERα36 – Another piece of the estrogen puzzle

(2015) Kamil Sołtysik et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Chromatin-Driven Behavior of Topologically Associating Domains

(2015) Filippo Ciabrelli et al.   JOURNAL OF MOLECULAR BIOLOGY

From the Women’s Health Initiative to the combination of estrogen and selective estrogen receptor modulators to avoid progestin addition

(2015) Marie-Cécile Valera et al.   MATURITAS

Estrogen receptor alpha phosphorylation and its functional impact in human breast cancer

(2015) Muralidharan Anbalagan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen receptor alpha-36 (ER-α36): A new player in human breast cancer

(2015) Zhao-Yi Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites to Alter the Breast Cancer Cell Transcriptome

(2015) Hector L. Franco et al.   MOLECULAR CELL

Structure of a Biologically Active Estrogen Receptor-Coactivator Complex on DNA

(2015) Ping Yi et al.   MOLECULAR CELL

Uterine Epithelial Estrogen Receptor-α Controls Decidualization via a Paracrine Mechanism

(2015) S. Pawar et al.   MOLECULAR ENDOCRINOLOGY

Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland

(2015) Zeynep Madak-Erdogan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

(2015) Assaf Rotem et al.   NATURE BIOTECHNOLOGY

Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling

(2015) Laure Maneix et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Catalog of Currently Documented Histone Modifications

(2015) Yingming Zhao et al.   Cold Spring Harbor Perspectives in Biology

Multiplex Eukaryotic Transcription (In)activation: Timing, Bursting and Cycling of a Ratchet Clock Mechanism

(2015) Katja N. Rybakova et al.   PLoS Computational Biology

Shear Stress–Initiated Signaling and Its Regulation of Endothelial Function

(2014) Jing Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Promoter or enhancer, what's the difference? Deconstruction of established distinctions and presentation of a unifying model

(2014) Robin Andersson   BIOESSAYS

Enhancer Activation Requires trans-Recruitment of a Mega Transcription Factor Complex

(2014) Zhijie Liu et al.   CELL

Membrane-Localized Estrogen Receptor α Is Required for Normal Organ Development and Function

(2014) Ali Pedram et al.   DEVELOPMENTAL CELL

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor   modulation, uncoupling nuclear and membrane activation

(2014) A. Abot et al.   EMBO Molecular Medicine

Aromatase and estrogen receptor α deficiency

(2014) Serdar E. Bulun   FERTILITY AND STERILITY

Functional and topological characteristics of mammalian regulatory domains

(2014) O. Symmons et al.   GENOME RESEARCH

Dynamic Estrogen Receptor Interactomes Control Estrogen-Responsive Trefoil Factor (TFF) Locus Cell-Specific Activities

(2014) J. Quintin et al.   MOLECULAR AND CELLULAR BIOLOGY

Novel Roles for ERK5 and Cofilin as Critical Mediators Linking ERα-Driven Transcription, Actin Reorganization, and Invasiveness in Breast Cancer

(2014) Zeynep Madak-Erdogan et al.   MOLECULAR CANCER RESEARCH

Minireview: Steroid-Regulated Paracrine Mechanisms Controlling Implantation

(2014) Sandeep Pawar et al.   MOLECULAR ENDOCRINOLOGY

Estrogen Induces Global Reorganization of Chromatin Structure in Human Breast Cancer Cells

(2014) Raphaël Mourad et al.   PLoS One

The estrogen receptor antagonist ICI 182,780 can act both as an agonist and an inverse agonist when estrogen receptor   AF-2 is modified

(2014) S. Moverare-Skrtic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide activity of unliganded estrogen receptor-α in breast cancer cells

(2014) Livia Caizzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule analysis of transcription factor binding at transcription sites in live cells

(2014) Tatsuya Morisaki et al.   Nature Communications

Inference of RNA Polymerase II Transcription Dynamics from Chromatin Immunoprecipitation Time Course Data

(2014) Ciira wa Maina et al.   PLoS Computational Biology

Tamoxifen Elicits Atheroprotection through Estrogen Receptor α AF-1 But Does Not Accelerate Reendothelialization

(2013) Coralie Fontaine et al.   AMERICAN JOURNAL OF PATHOLOGY

Key Role of Estrogens and Endothelial Estrogen Receptor α in Blood Flow–Mediated Remodeling of Resistance Arteries

(2013) K. Tarhouni et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genome-wide analysis uncovers high frequency, strong differential chromosomal interactions and their associated epigenetic patterns in E2-mediated gene regulation

(2013) Junbai Wang et al.   BMC GENOMICS

HDL and endothelial protection

(2013) A Tran-Dinh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Amplification of Distant Estrogen Response Elements Deregulates Target Genes Associated with Tamoxifen Resistance in Breast Cancer

(2013) Pei-Yin Hsu et al.   CANCER CELL

Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

(2013) M. P. H. M. Jansen et al.   CANCER RESEARCH

Prevention of Obesity and Insulin Resistance by Estrogens Requires ER  Activation Function-2 (ER AF-2), Whereas ER AF-1 Is Dispensable

(2013) S. Handgraaf et al.   DIABETES

The AF-1 Activation Function of Estrogen Receptor α Is Necessary and Sufficient for Uterine Epithelial Cell Proliferation In Vivo

(2013) Anne Abot et al.   ENDOCRINOLOGY

Enhancer transcripts mark active estrogen receptor binding sites

(2013) N. Hah et al.   GENOME RESEARCH

Estrogen Receptor α L543A,L544A Mutation Changes Antagonists to Agonists, Correlating with the Ligand Binding Domain Dimerization Associated with DNA Binding Activity

(2013) Yukitomo Arao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of the tissue selective estrogen complex (TSEC)

(2013) Barry S. Komm et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Allosteric Controls of Nuclear Receptor Function in the Regulation of Transcription

(2013) Isabelle Billas et al.   JOURNAL OF MOLECULAR BIOLOGY

Tissue-selective estrogen complexes for postmenopausal women

(2013) Sebastian Mirkin et al.   MATURITAS

Timing hypothesis for postmenopausal hormone therapy

(2013) Thomas B. Clarkson et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Proteomic Analysis of Coregulators Bound to ERα on DNA and Nucleosomes Reveals Coregulator Dynamics

(2013) Charles E. Foulds et al.   MOLECULAR CELL

Integrative genomics of gene and metabolic regulation by estrogen receptors   and  , and their coregulators

(2013) Z. Madak-Erdogan et al.   Molecular Systems Biology

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

(2013) Wenbo Li et al.   NATURE

Topology of mammalian developmental enhancers and their regulatory landscapes

(2013) Wouter de Laat et al.   NATURE

Chromatin connectivity maps reveal dynamic promoter–enhancer long-range associations

(2013) Yubo Zhang et al.   NATURE

Dynamic regulation of transcriptional states by chromatin and transcription factors

(2013) Ty C. Voss et al.   NATURE REVIEWS GENETICS

Activation of mitogen- and stress-activated kinase 1 is required for proliferation of breast cancer cells in response to estrogens or progestins

(2013) D Reyes et al.   ONCOGENE

Mutation of the palmitoylation site of estrogen receptor   in vivo reveals tissue-specific roles for membrane versus nuclear actions

(2013) M. Adlanmerini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface

(2013) I. J. De Vries-van Leeuwen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

(2013) J. Zuin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen hormone physiology: Reproductive findings from estrogen receptor mutant mice

(2013) Katherine J. Hamilton et al.   Reproductive Biology

Estrogen Reduces Lipid Content in the Liver Exclusively from Membrane Receptor Signaling

(2013) A. Pedram et al.   Science Signaling

Cell-specific integration of nuclear receptor function at the genome

(2013) Logan J. Everett et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Endogenous Purification Reveals GREB1 as a Key Estrogen Receptor Regulatory Factor

(2013) Hisham Mohammed et al.   Cell Reports

Development of an Illumina-based ChIP-exonuclease method provides insight into FoxA1-DNA binding properties

(2013) Aurelien A Serandour et al.   GENOME BIOLOGY

RNA Sequencing of MCF-7 Breast Cancer Cells Identifies Novel Estrogen-Responsive Genes with Functional Estrogen Receptor-Binding Sites in the Vicinity of Their Transcription Start Sites

(2013) Ryonosuke Yamaga et al.   Hormones & Cancer

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

(2012) Guoliang Li et al.   CELL

Effects of the Conjugated Equine Estrogen/Bazedoxifene Tissue-Selective Estrogen Complex (TSEC) on Mammary Gland and Breast Cancer in Mice

(2012) Yan Song et al.   ENDOCRINOLOGY

GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility

(2012) V. Theodorou et al.   GENOME RESEARCH

Breast density changes in a randomized controlled trial evaluating bazedoxifene/conjugated estrogens

(2012) Jennifer A. Harvey et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Palmitoylation Regulates 17β-Estradiol-Induced Estrogen Receptor-α Degradation and Transcriptional Activity

(2012) Piergiorgio La Rosa et al.   MOLECULAR ENDOCRINOLOGY

Research Resource: Whole-Genome Estrogen Receptor α Binding in Mouse Uterine Tissue Revealed by ChIP-Seq

(2012) Sylvia C. Hewitt et al.   MOLECULAR ENDOCRINOLOGY

Prehistoric proteins: Raising the dead

(2012) Helen Pearson   NATURE

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

(2012) Caryn S. Ross-Innes et al.   NATURE

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers

(2012) Aurélien A. Sérandour et al.   NUCLEIC ACIDS RESEARCH

Transactivating function (AF) 2-mediated AF-1 activity of estrogen receptor   is crucial to maintain male reproductive tract function

(2012) Y. Arao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin signatures of active enhancers

(2012) salvatore spicuglia et al.   Nucleus

Physiological Remodelling of the Maternal Uterine Circulation during Pregnancy

(2011) Maurizio Mandala et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Steroid Receptor RNA Activator – A nuclear receptor coregulator with multiple partners: Insights and challenges

(2011) Shane M. Colley et al.   BIOCHIMIE

Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation

(2011) Oli MV Grober et al.   BMC GENOMICS

A Rapid, Extensive, and Transient Transcriptional Response to Estrogen Signaling in Breast Cancer Cells

(2011) Nasun Hah et al.   CELL

AP-2γ regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription

(2011) Si Kee Tan et al.   EMBO JOURNAL

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer

(2011) Wilbert Zwart et al.   EMBO JOURNAL

Minireview: Recent Advances in Extranuclear Steroid Receptor Actions

(2011) Stephen R. Hammes et al.   ENDOCRINOLOGY

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

(2011) A. A. Serandour et al.   GENOME RESEARCH

Exploration of Dimensions of Estrogen Potency

(2011) M. Jeyakumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-nuclear Estrogen Receptor Signaling in the Endothelium

(2011) Qian Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles for Oestrogen Receptor β in Adult Brain Function

(2011) R. J. Handa et al.   JOURNAL OF NEUROENDOCRINOLOGY

Signaling functions of ubiquitin in the 17β-estradiol (E2):estrogen receptor (ER) α network

(2011) Piergiorgio La Rosa et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Preventive therapy for breast cancer: a consensus statement

(2011) Jack Cuzick et al.   LANCET ONCOLOGY

Impact of chromatin structure and dynamics on PR signaling. The initial steps in hormonal gene regulation

(2011) Miguel Beato et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Role of phosphorylation in progesterone receptor signaling and specificity

(2011) Christy R. Hagan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Splice isoform estrogen receptors as integral transmembrane proteins

(2011) Kyung Hee Kim et al.   MOLECULAR BIOLOGY OF THE CELL

DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors

(2011) Ali Pedram et al.   MOLECULAR BIOLOGY OF THE CELL

The Selective Estrogen Receptor Modulator Bazedoxifene Inhibits Hormone-Independent Breast Cancer Cell Growth and Down-Regulates Estrogen Receptor   and Cyclin D1

(2011) J. S. Lewis-Wambi et al.   MOLECULAR PHARMACOLOGY

Cellular reprogramming by the conjoint action of ER , FOXA1, and GATA3 to a ligand-inducible growth state

(2011) S. L. Kong et al.   Molecular Systems Biology

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Roles of transactivating functions 1 and 2 of estrogen receptor-  in bone

(2011) A. E. Borjesson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen receptor   AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators

(2011) Y. Arao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation function 2 (AF2) of estrogen receptor-α is required for the atheroprotective action of estradiol but not to accelerate endothelial healing

(2011) Audrey Billon-Galés et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pioneer factors: directing transcriptional regulators within the chromatin environment

(2011) Luca Magnani et al.   TRENDS IN GENETICS

The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function

(2011) Matthias R. Meyer et al.   VASCULAR PHARMACOLOGY

Are ‘omics of estrogen receptors defining potential targets for breast cancer treatment?

(2011) Raphaël Métivier   Epigenomics

PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

(2011) Luca Magnani et al.   PLoS Genetics

Endothelial Estrogen Receptor α Plays an Essential Role in the Coronary and Myocardial Protective Effects of Estradiol in Ischemia/Reperfusion

(2010) Julie Favre et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Estrogen Receptors and Endothelium

(2010) Jean-François Arnal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genome-Wide Mapping of Estrogen Receptor-β–Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1

(2010) Chunyan Zhao et al.   CANCER RESEARCH

Bursts and pulses: insights from single cell studies into transcriptional mechanisms

(2010) Jonathan R Chubb et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Biological and biochemical consequences of global deletion of exon 3 from the ERα gene

(2010) Sylvia C. Hewitt et al.   FASEB JOURNAL

Growth factor stimulation induces a distinct ER  cistrome underlying breast cancer endocrine resistance

(2010) M. Lupien et al.   GENES & DEVELOPMENT

A CTCF-independent role for cohesin in tissue-specific transcription

(2010) D. Schmidt et al.   GENOME RESEARCH

Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping

(2010) P.-Y. Hsu et al.   GENOME RESEARCH

CCCTC-binding Factor Acts Upstream of FOXA1 and Demarcates the Genomic Response to Estrogen

(2010) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steroid Receptor Coactivator (SRC) Family: Masters of Systems Biology

(2010) Brian York et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen

(2010) W. Zwart et al.   JOURNAL OF CELL SCIENCE

Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

(2010) Ken L. Chambliss et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid progress for non-nuclear estrogen receptor signaling

(2010) Michael E. Mendelsohn et al.   JOURNAL OF CLINICAL INVESTIGATION

American Society of Clinical Oncology Clinical Practice Guideline: Update on Adjuvant Endocrine Therapy for Women With Hormone Receptor–Positive Breast Cancer

(2010) Harold J. Burstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Ex3αERKO male infertility phenotype recapitulates the αERKO male phenotype

(2010) Eugenia H Goulding et al.   JOURNAL OF ENDOCRINOLOGY

Genome-Wide Analysis of Estrogen Receptor   DNA Binding and Tethering Mechanisms Identifies Runx1 as a Novel Tethering Factor in Receptor-Mediated Transcriptional Activation

(2010) J. D. Stender et al.   MOLECULAR AND CELLULAR BIOLOGY

Genomic Collaboration of Estrogen Receptor   and Extracellular Signal-Regulated Kinase 2 in Regulating Gene and Proliferation Programs

(2010) Z. Madak-Erdogan et al.   MOLECULAR AND CELLULAR BIOLOGY

Estrogen Receptor-β Prevents Cardiac Fibrosis

(2010) Ali Pedram et al.   MOLECULAR ENDOCRINOLOGY

Integrative model of genomic factors for determining binding site selection by estrogen receptor-α

(2010) Roy Joseph et al.   Molecular Systems Biology

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

FOXA1 is a key determinant of estrogen receptor function and endocrine response

(2010) Antoni Hurtado et al.   NATURE GENETICS

Safety and tolerability of bazedoxifene in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled phase 3 trial

(2010) T. J. de Villiers et al.   OSTEOPOROSIS INTERNATIONAL

Hormone Action in the Mammary Gland

(2010) C. Brisken et al.   Cold Spring Harbor Perspectives in Biology

Estrogen replacement restores flow-induced vasodilation in coronary arterioles of aged and ovariectomized rats

(2009) Amanda J. LeBlanc et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Coronary heart disease and menopause management: The swinging pendulum of HRT

(2009) John C. Stevenson et al.   ATHEROSCLEROSIS

Nuclear Receptor Coregulators in Cancer Biology

(2009) B. W. O'Malley et al.   CANCER RESEARCH

Endothelial Estrogen Receptor-α Plays a Crucial Role in the Atheroprotective Action of 17β-Estradiol in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Audrey Billon-Galés et al.   CIRCULATION

Endothelial Dysfunction

(2009) Paul M. Vanhoutte   CIRCULATION JOURNAL

Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity

(2009) Elvira Haas et al.   CIRCULATION RESEARCH

Mechanisms of action of estrogen receptors in vascular cells: relevance for menopause and aging

(2009) T. Simoncini   CLIMACTERIC

ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands

(2009) Willem-Jan Welboren et al.   EMBO JOURNAL

Cistromics of hormone-dependent cancer

(2009) Mathieu Lupien et al.   ENDOCRINE-RELATED CANCER

G Protein-Coupled Receptor 30: Estrogen Receptor or Collaborator?

(2009) Ellis R. Levin   ENDOCRINOLOGY

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

(2009) J. Eeckhoute et al.   GENOME RESEARCH

Estrogen-mediated Regulation of Igf1 Transcription and Uterine Growth Involves Direct Binding of Estrogen Receptor α to Estrogen-responsive Elements

(2009) Sylvia C. Hewitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene expression profiling studies of three SERMs and their conjugated estrogen combinations in human breast cancer cells: Insights into the unique antagonistic effects of bazedoxifene on conjugated estrogens

(2009) Ken C.N. Chang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Membrane-initiated actions of estrogen on the endothelium

(2009) Kyung Hee Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

DNA Binding by Estrogen Receptor-α Is Essential for the Transcriptional Response to Estrogen in the Liver and the Uterus

(2009) Dörthe L. Ahlbory-Dieker et al.   MOLECULAR ENDOCRINOLOGY

Genome-Wide Dynamics of Chromatin Binding of Estrogen Receptors α and β: Mutual Restriction and Competitive Site Selection

(2009) Tze Howe Charn et al.   MOLECULAR ENDOCRINOLOGY

An oestrogen-receptor-α-bound human chromatin interactome

(2009) Melissa J. Fullwood et al.   NATURE

eNOS Activation by Physical Forces: From Short-Term Regulation of Contraction to Chronic Remodeling of Cardiovascular Tissues

(2009) J.-L. Balligand et al.   PHYSIOLOGICAL REVIEWS

Estradiol Regulates Expression of Estrogen Receptor ERα46 in Human Macrophages

(2009) Amy J. Murphy et al.   PLoS One

The transactivating function 1 of estrogen receptor α is dispensable for the vasculoprotective actions of 17β-estradiol

(2009) Audrey Billon-Galés et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A critical review of fundamental controversies in the field of GPR30 research

(2009) Gernot Langer et al.   STEROIDS

Nkx3-1 and LEF-1 Function as Transcriptional Inhibitors of Estrogen Receptor Activity

(2008) K. A. Holmes et al.   CANCER RESEARCH

FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

(2008) Mathieu Lupien et al.   CELL

Steroid Hormones Control CircadianElovl3Expression in Mouse Liver

(2008) Annelie Brolinson et al.   ENDOCRINOLOGY

Effects of Various Selective Estrogen Receptor Modulators with or without Conjugated Estrogens on Mouse Mammary Gland

(2008) Bryan J. Peano et al.   ENDOCRINOLOGY

Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice

(2008) Jörg Isensee et al.   ENDOCRINOLOGY

Developmental Phenotype of a Membrane Only Estrogen Receptor α (MOER) Mouse

(2008) Ali Pedram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional analysis of estrogen receptor alpha variant mRNAs in colorectal cancers and their matched normal colorectal tissues

(2008) Haiping Jiang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Generation and characterization of a complete null estrogen receptor α mouse using Cre/LoxP technology

(2008) Ming Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

New insights into the classical and non-classical actions of estrogen: Evidence from estrogen receptor knock-out and knock-in mice

(2008) Melissa A. McDevitt et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of Estrogen Rapid Signaling through Arginine Methylation by PRMT1

(2008) Muriel Le Romancer et al.   MOLECULAR CELL

Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase

(2008) Krithika Subramanian et al.   MOLECULAR CELL

Nuclear and Extranuclear Pathway Inputs in the Regulation of Global Gene Expression by Estrogen Receptors

(2008) Zeynep Madak-Erdogan et al.   MOLECULAR ENDOCRINOLOGY

Sterility and absence of histopathological defects in nonreproductive organs of a mouse ER -null mutant

(2008) M. C. Antal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter

(2008) T. S. Karpova et al.   SCIENCE

Membrane association of estrogen receptor α and β influences 17β-estradiol-mediated cancer cell proliferation

(2008) M MARINO et al.   STEROIDS