Role of Circular RNAs in the Regulation of Immune Cells in Response to Cancer Therapies

Drivers of dynamic intra-tumor heterogeneity and phenotypic plasticity

(2021) Antara Biswas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Tumor immune microenvironment-based classifications of bladder cancer for enhancing the response rate of immunotherapy

(2021) Jialin Meng et al.   Molecular Therapy-Oncolytics

Circular RNA CHST15 Sponges miR-155-5p and miR-194-5p to Promote the Immune Escape of Lung Cancer Cells Mediated by PD-L1

(2021) Jianru Yang et al.   Frontiers in Oncology

Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies

(2021) Sabah Nisar et al.   Frontiers in Cell and Developmental Biology

Downregulation of hsa_circ_0074854 Suppresses the Migration and Invasion in Hepatocellular Carcinoma via Interacting with HuR and via Suppressing Exosomes-Mediated Macrophage M2 Polarization

(2021) Yong Wang et al.   International Journal of Nanomedicine

Tumour immune microenvironment biomarkers predicting cytotoxic chemotherapy efficacy in colorectal cancer

(2021) Kate Wilkinson et al.   JOURNAL OF CLINICAL PATHOLOGY

Tumor Microenvironmental Competitive Endogenous RNA Network and Immune Cells Act as Robust Prognostic Predictor of Acute Myeloid Leukemia

(2021) Yaqi Cheng et al.   Frontiers in Oncology

circPTPN22 attenuates immune microenvironment of pancreatic cancer via STAT3 acetylation

(2021) Yuan He et al.   CANCER GENE THERAPY

The role of lncRNAs and circRNAs in the PD-1/PD-L1 pathway in cancer immunotherapy

(2021) Wenxiao Jiang et al.   Molecular Cancer

Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit

(2021) Theodora Katopodi et al.   Scientific Reports

Mammalian circular RNAs result largely from splicing errors

(2021) Chuan Xu et al.   Cell Reports

Immune Microenvironment Change and Involvement of Circular RNAs in TIL Cells of Recurrent Nasopharyngeal Carcinoma

(2021) Yumin Wang et al.   Frontiers in Cell and Developmental Biology

Clinical implications of intratumor heterogeneity: challenges and opportunities

(2020) Santiago Ramón y Cajal et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Tumor Microenvironment

(2020) Borros Arneth   Medicina-Lithuania

circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma

(2020) JunFeng Wang et al.   Cell Death & Disease

Metformin Enhances the Antitumor Activity of CD8+ T Lymphocytes via the AMPK–miR-107–Eomes–PD-1 Pathway

(2020) Zhen Zhang et al.   JOURNAL OF IMMUNOLOGY

Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis

(2020) Xiao-Yong Huang et al.   Molecular Cancer

The expanding regulatory mechanisms and cellular functions of circular RNAs

(2020) Ling-Ling Chen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biological Roles and Mechanisms of Circular RNA in Human Cancers

(2020) Qing Tang et al.   OncoTargets and Therapy

Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma

(2020) Peng-Fei Zhang et al.   Molecular Cancer

Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p- TGF-β1 axis

(2020) Anquan Shang et al.   Molecular Cancer

Plasma Level of Circular RNA hsa_circ_0000190 Correlates with Tumor Progression and Poor Treatment Response in Advanced Lung Cancers

(2020) Yung-Hung Luo et al.   Cancers

Circular RNA circ-CPA4/ let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC)

(2020) Weijun Hong et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Construction of a circRNA-miRNA-mRNA Network Related to Macrophage Infiltration in Hepatocellular Carcinoma

(2020) Peitao Zhou et al.   Frontiers in Genetics

Emerging Roles of Exosomal Circular RNAs in Cancer

(2020) Takahiro Seimiya et al.   Frontiers in Cell and Developmental Biology

Cancer immunoediting: A game theoretical approach

(2020) Fatemeh Tavakoli et al.   In Silico Biology

Programmed Death Ligand 1 (PD-L1) as a Predictive Biomarker for Pembrolizumab Therapy in Patients with Advanced Non-Small-Cell Lung Cancer (NSCLC)

(2019) Lorena Incorvaia et al.   ADVANCES IN THERAPY

Circular RNAs: Biogenesis, Mechanism, and Function in Human Cancers

(2019) Xing Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immune checkpoint inhibitors of PD-L1 as cancer therapeutics

(2019) Akintunde Akinleye et al.   Journal of Hematology & Oncology

Biogenesis, functions and clinical significance of circRNAs in gastric cancer

(2019) Chan Shan et al.   Molecular Cancer

Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: role of circ_0000977/miR-153 axis

(2019) Zheng-Lin Ou et al.   RNA Biology

Circular RNAs

(2019) Dong Li et al.   CHINESE MEDICAL JOURNAL

Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells

(2019) Yeni Romero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Nefarious Nexus of Noncoding RNAs in Cancer

(2018) Eleni Anastasiadou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Believer’s Overview of Cancer Immunosurveillance and Immunotherapy

(2018) Olivera J. Finn   JOURNAL OF IMMUNOLOGY

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

The Biogenesis, Functions, and Challenges of Circular RNAs

(2018) Xiang Li et al.   MOLECULAR CELL

Circular RNAs: Promising Biomarkers for Human Diseases

(2018) Zhongrong Zhang et al.   EBioMedicine

circRNA of AR‑suppressed PABPC1 91�bp enhances the cytotoxicity of natural killer cells against hepatocellular carcinoma via upregulating UL16 binding protein 1

(2018) Yuanming Ma et al.   Oncology Letters

Circular RNA involvement in aging: An emerging player with great potential

(2018) Hongcai Cai et al.   MECHANISMS OF AGEING AND DEVELOPMENT

CircRNA: functions and properties of a novel potential biomarker for cancer

(2017) Shujuan Meng et al.   Molecular Cancer

Exosomes: A Novel Strategy for Treatment and Prevention of Diseases

(2017) Jiaqi Wang et al.   Frontiers in Pharmacology

The emerging landscape of circular RNA in life processes

(2016) Shibin Qu et al.   RNA Biology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of circRNA biogenesis

(2015) Ling-Ling Chen et al.   RNA Biology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY