Engineering ligand-specific biosensors for aromatic amino acids and neurochemicals

Metabolic engineering for the production of l-phenylalanine in Escherichia coli

(2019) Xiaozhen Liu et al.   3 Biotech

A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology

(2019) Haiwei Chen et al.   CELL

Model-guided mechanism discovery and parameter selection for directed evolution

(2019) Sarah C. Stainbrook et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Computational design of a modular protein sense-response system

(2019) Anum A. Glasgow et al.   SCIENCE

Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A

(2019) Muhammad Rafehi et al.   Frontiers in Pharmacology

Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion

(2018) Yogesh Bhattarai et al.   Cell Host & Microbe

Directed evolution of a synthetic phylogeny of programmable Trp repressors

(2018) Jared W. Ellefson et al.   Nature Chemical Biology

Molecular Toolkit for Gene Expression Control and Genome Modification in Rhodococcus opacus PD630

(2018) Drew M. DeLorenzo et al.   ACS Synthetic Biology

Transcription factor-based biosensor for detection of phenylalanine and tyrosine in urine for diagnosis of phenylketonuria

(2018) Chieh Lin et al.   ANALYTICA CHIMICA ACTA

De novo design of a fluorescence-activating β-barrel

(2018) Jiayi Dou et al.   NATURE

Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors

(2018) Adam J. Meyer et al.   Nature Chemical Biology

Dynamics of sequestration-based gene regulatory cascades

(2017) Tatenda Shopera et al.   NUCLEIC ACIDS RESEARCH

AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production

(2017) Simon Schäper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Chemical and Metabolite Sensors for Rhodococcus opacus PD630

(2017) Drew M. DeLorenzo et al.   ACS Synthetic Biology

Rapid and Programmable Protein Mutagenesis Using Plasmid Recombineering

(2017) Sean A. Higgins et al.   ACS Synthetic Biology

A Simple Combinatorial Codon Mutagenesis Method for Targeted Protein Engineering

(2017) Ketaki D. Belsare et al.   ACS Synthetic Biology

Screening of an Escherichia coli promoter library for a phenylalanine biosensor

(2016) Regina Mahr et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Programmable control of bacterial gene expression with the combined CRISPR and antisense RNA system

(2016) Young Je Lee et al.   NUCLEIC ACIDS RESEARCH

Selectivity and Specificity: Pros and Cons in Sensing

(2016) William J. Peveler et al.   ACS Sensors

Engineering an allosteric transcription factor to respond to new ligands

(2015) Noah D Taylor et al.   NATURE METHODS

Phenylketonuria Scientific Review Conference: State of the science and future research needs

(2014) Kathryn M. Camp et al.   MOLECULAR GENETICS AND METABOLISM

Finely Tuned Regulation of the Aromatic Amine Degradation Pathway in Escherichia coli

(2013) J. Zeng et al.   JOURNAL OF BACTERIOLOGY

Small-molecule ligand docking into comparative models with Rosetta

(2013) Steven A Combs et al.   Nature Protocols

Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)

(2013) Sergey Lyskov et al.   PLoS One

High-Resolution Comparative Modeling with RosettaCM

(2013) Yifan Song et al.   STRUCTURE

Age-related changes in serum amino acids concentrations in healthy individuals

(2012) Takanori Kouchiwa et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Tyramine and Phenylethylamine Biosynthesis by Food Bacteria

(2012) Angela Marcobal et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Automated design of synthetic ribosome binding sites to control protein expression

(2009) Howard M Salis et al.   NATURE BIOTECHNOLOGY