TIGIT Induces (CD3+) T Cell Dysfunction in Colorectal Cancer by Inhibiting Glucose Metabolism
出版年份 2021 全文链接
标题
TIGIT Induces (CD3+) T Cell Dysfunction in Colorectal Cancer by Inhibiting Glucose Metabolism
作者
关键词
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出版物
Frontiers in Immunology
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-09-29
DOI
10.3389/fimmu.2021.688961
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Next generation of immune checkpoint inhibitors and beyond
- (2021) Julian A. Marin-Acevedo et al. Journal of Hematology & Oncology
- Synergic effect of PD-1 blockade and endostar on the PI3K/AKT/mTOR-mediated autophagy and angiogenesis in Lewis lung carcinoma mouse model
- (2020) Jing Wu et al. BIOMEDICINE & PHARMACOTHERAPY
- Transcriptional Regulation of Cancer Immune Checkpoints: Emerging Strategies for Immunotherapy
- (2020) Simran Venkatraman et al. Vaccines
- The prognostic value of CD3+ tumor-infiltrating lymphocytes for stage II colon cancer according to use of adjuvant chemotherapy: A large single-institution cohort study
- (2020) Edoardo Francini et al. Translational Oncology
- TIGIT and PD-1 mark intratumoral T cells with reduced effector function in B-cell non-Hodgkin lymphoma
- (2019) Sarah E Josefsson et al. Cancer Immunology Research
- Navigating metabolic pathways to enhance antitumour immunity and immunotherapy
- (2019) Xiaoyun Li et al. Nature Reviews Clinical Oncology
- PD-1/PD-L1 blockade rescue exhausted CD8+ T cells in gastrointestinal stromal tumours via the PI3K/Akt/mTOR signalling pathway
- (2019) Rui Zhao et al. CELL PROLIFERATION
- Immune exhaustion of T cells in alveolar echinococcosis patients and its reversal by blocking checkpoint receptor TIGIT in a murine model
- (2019) Chuanshan Zhang et al. HEPATOLOGY
- Blockade of TIGIT/CD155 Signaling Reverses T-cell Exhaustion and Enhances Antitumor Capability in Head and Neck Squamous Cell Carcinoma
- (2019) Lei Wu et al. Cancer Immunology Research
- Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response
- (2019) Shamir Cassim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Therapeutic prospects of targeting myeloid-derived suppressor cells and immune checkpoints in cancer
- (2018) Salman M Toor et al. IMMUNOLOGY AND CELL BIOLOGY
- Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors
- (2018) Kristian M. Hargadon et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM
- (2018) Alice L. Hung et al. OncoImmunology
- Interaction of PVR/PVRL2 with TIGIT/DNAM-1 as a novel immune checkpoint axis and therapeutic target in cancer
- (2018) Hauke Stamm et al. MAMMALIAN GENOME
- Correlation of T Cell Immunoglobulin and ITIM Domain (TIGIT) and Programmed Death 1 (PD-1) with Clinicopathological Characteristics of Renal Cell Carcinoma May Indicate Potential Targets for Treatment
- (2018) Xin Hong et al. MEDICAL SCIENCE MONITOR
- Progress of immune checkpoint therapy in the clinic (Review)
- (2018) Yiqun Fan et al. ONCOLOGY REPORTS
- Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression
- (2018) Christopher M. Rice et al. Nature Communications
- Intrinsic Expression of Immune Checkpoint Molecule TIGIT Could Help Tumor Growth in vivo by Suppressing the Function of NK and CD8+ T Cells
- (2018) Xiu-Man Zhou et al. Frontiers in Immunology
- CXCR5 + CD8 + T cells potently infiltrate pancreatic tumors and present high functionality
- (2017) Minghui Bai et al. EXPERIMENTAL CELL RESEARCH
- Immune checkpoint inhibitors in cancer therapy: a focus on T-regulatory cells
- (2017) Varun Sasidharan Nair et al. IMMUNOLOGY AND CELL BIOLOGY
- Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
- (2017) Kenji Chamoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging targets in cancer immunotherapy
- (2017) Samantha Burugu et al. SEMINARS IN CANCER BIOLOGY
- Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals
- (2017) Johanna Tauriainen et al. Scientific Reports
- TIGIT overexpression diminishes the function of CD4 T cells and ameliorates the severity of rheumatoid arthritis in mouse models
- (2016) Weigong Zhao et al. EXPERIMENTAL CELL RESEARCH
- Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion
- (2016) Bertram Bengsch et al. IMMUNITY
- Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
- (2016) Ana C. Anderson et al. IMMUNITY
- Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions
- (2015) Clovis S. Palmer et al. Frontiers in Immunology
- The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function
- (2014) Robert J. Johnston et al. CANCER CELL
- Metabolic Pathways in Immune Cell Activation and Quiescence
- (2013) Erika L. Pearce et al. IMMUNITY
- Delineating metabolic signatures of head and neck squamous cell carcinoma: Phospholipase A2, a potential therapeutic target
- (2012) Pratima Tripathi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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