Large-scale analysis of imprinting in naive human pluripotent stem cells reveals recurrent aberrations and a potential link to FGF signaling

Signal regulators of human naïve pluripotency

(2020) Adeleh Taei et al.   EXPERIMENTAL CELL RESEARCH

Transient inhibition of mTOR in human pluripotent stem cells enables robust formation of mouse-human chimeric embryos

(2020) Zhixing Hu et al.   Science Advances

Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation

(2020) Chenrui An et al.   Cell Stem Cell

Acquired genetic changes in human pluripotent stem cells: origins and consequences

(2020) Jason Halliwell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances

(2020) Ana Monteagudo-Sánchez et al.   NUCLEIC ACIDS RESEARCH

Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells

(2020) Giuliano Giuseppe Stirparo et al.   Cell Stem Cell

Cancer-Related Mutations Identified in Primed Human Pluripotent Stem Cells

(2020) Yishai Avior et al.   Cell Stem Cell

ZNF445 is a primary regulator of genomic imprinting

(2019) Nozomi Takahashi et al.   GENES & DEVELOPMENT

Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution

(2019) Tobias Messmer et al.   Cell Reports

Genomic Imprinting and Physiological Processes in Mammals

(2019) Valter Tucci et al.   CELL

Defining Human Pluripotency

(2019) Atilgan Yilmaz et al.   Cell Stem Cell

A Chemically Defined Feeder-free System for the Establishment and Maintenance of the Human Naive Pluripotent State

(2019) Iwona Szczerbinska et al.   Stem Cell Reports

Recent insights into the naïve state of human pluripotency and its applications

(2019) Chen Dong et al.   EXPERIMENTAL CELL RESEARCH

Correction: Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast (doi: 10.1242/dev.158501)

(2018) Giuliano G. Stirparo et al.   DEVELOPMENT

Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells

(2018) Bruno Di Stefano et al.   NATURE METHODS

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

(2018) Roelof J. C. Kluin et al.   BMC BIOINFORMATICS

Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics

(2018) Stefano Giulitti et al.   NATURE CELL BIOLOGY

Zinc finger protein 274 regulates imprinted expression of transcripts in Prader-Willi syndrome neurons

(2017) Maéva Langouët et al.   HUMAN MOLECULAR GENETICS

Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells

(2017) Jiho Choi et al.   NATURE

Derivation of ground-state female ES cells maintaining gamete-derived DNA methylation

(2017) Masaki Yagi et al.   NATURE

Large-Scale Analysis of Loss of Imprinting in Human Pluripotent Stem Cells

(2017) Shiran Bar et al.   Cell Reports

GSA: Genome Sequence Archive *

(2017) Yanqing Wang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

(2016) Sophie Petropoulos et al.   CELL

Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory

(2016) William A. Pastor et al.   Cell Stem Cell

Molecular Criteria for Defining the Naive Human Pluripotent State

(2016) Thorold W. Theunissen et al.   Cell Stem Cell

Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq

(2016) Uri Weissbein et al.   Nature Communications

Differentiation of Human Parthenogenetic Pluripotent Stem Cells Reveals Multiple Tissue- and Isoform-Specific Imprinted Transcripts

(2015) Yonatan Stelzer et al.   Cell Reports

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

Comparable Frequencies of Coding Mutations and Loss of Imprinting in Human Pluripotent Cells Derived by Nuclear Transfer and Defined Factors

(2014) Bjarki Johannesson et al.   Cell Stem Cell

Abnormalities in human pluripotent cells due to reprogramming mechanisms

(2014) Hong Ma et al.   NATURE

The role of genomic imprinting in biology and disease: an expanding view

(2014) Jo Peters   NATURE REVIEWS GENETICS

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

(2013) Gabriella Ficz et al.   Cell Stem Cell

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives

(2012) Kristopher L. Nazor et al.   Cell Stem Cell

Dynamic CpG island methylation landscape in oocytes and preimplantation embryos

(2011) Sébastien A Smallwood et al.   NATURE GENETICS

Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci

(2010) Anthony P. Popkie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription is required for establishment of germline methylation marks at imprinted genes

(2009) M. Chotalia et al.   GENES & DEVELOPMENT

Clone- and Gene-Specific Aberrations of Parental Imprinting in Human Induced Pluripotent Stem Cells

(2009) Marjorie Pick et al.   STEM CELLS