The role of genomic imprinting in biology and disease: an expanding view

Dosage-sensitivity of imprinted genes expressed in the brain: 15q11–q13 and neuropsychiatric illness: Figure 1

(2013) Gráinne I. McNamara et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

(2013) Jeannie T. Lee et al.   CELL

Imprinted Igf2r silencing depends on continuous Airn lncRNA expression and is not restricted to a developmental window

(2013) F. Santoro et al.   DEVELOPMENT

Elevated blood pressure, heart rate and body temperature in mice lacking the XLαs protein of theGnaslocus is due to increased sympathetic tone

(2013) Nicolas Nunn et al.   EXPERIMENTAL PHYSIOLOGY

A Prader–Willi locus lncRNA cloud modulates diurnal genes and energy expenditure

(2013) Weston T. Powell et al.   HUMAN MOLECULAR GENETICS

PaternalGNASMutations Lead to Severe Intrauterine Growth Retardation (IUGR) and Provide Evidence for a Role of XLαs in Fetal Development

(2013) Nicolas Richard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Recommendations for the investigation of animal models of Prader–Willi syndrome

(2013) James L. Resnick et al.   MAMMALIAN GENOME

Brain-expressed imprinted genes and adult behaviour: the example of Nesp and Grb10

(2013) Claire L. Dent et al.   MAMMALIAN GENOME

Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence

(2013) Aparna Venkatraman et al.   NATURE

Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism

(2013) Christian P Schaaf et al.   NATURE GENETICS

Gene Dosage Effects at the Imprinted Gnas Cluster

(2013) Simon T. Ball et al.   PLoS One

Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis

(2013) Jesse D. Riordan et al.   PLoS Genetics

Magel2 Is Required for Leptin-Mediated Depolarization of POMC Neurons in the Hypothalamic Arcuate Nucleus in Mice

(2013) Rebecca E. Mercer et al.   PLoS Genetics

Maternal Inheritance of a Promoter Variant in the Imprinted PHLDA2 Gene Significantly Increases Birth Weight

(2012) Miho Ishida et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome

(2012) Wei Xie et al.   CELL

Imprinted Gene Dosage Is Critical for the Transition to Independent Life

(2012) Marika Charalambous et al.   Cell Metabolism

Gsα Deficiency in the Paraventricular Nucleus of the Hypothalamus Partially Contributes to Obesity Associated with Gsα Mutations

(2012) Min Chen et al.   ENDOCRINOLOGY

Paternal uniparental disomy 14 and related disorders

(2012) Masayo Kagami et al.   Epigenetics

Loss of the Prader–Willi obesity syndrome protein necdin promotes adipogenesis

(2012) Jason Russell Bush et al.   GENE

Relative Functions of Gαs and its Extra Large Variant XLαs in the Endocrine System

(2012) M Bastepe   HORMONE AND METABOLIC RESEARCH

Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a

(2012) Linyan Meng et al.   HUMAN MOLECULAR GENETICS

Parental imprinting regulates insulin-like growth factor signaling: a Rosetta Stone for understanding the biology of pluripotent stem cells, aging and cancerogenesis

(2012) M Z Ratajczak et al.   LEUKEMIA

Beyond knockouts: cre resources for conditional mutagenesis

(2012) Stephen A. Murray et al.   MAMMALIAN GENOME

The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping

(2012) Steve D. M. Brown et al.   MAMMALIAN GENOME

The mammalian gene function resource: the international knockout mouse consortium

(2012) Allan Bradley et al.   MAMMALIAN GENOME

New Mutations at the Imprinted Gnas Cluster Show Gene Dosage Effects of Gs  in Postnatal Growth and Implicate XL s in Bone and Fat Metabolism but Not in Suckling

(2012) S. A. Eaton et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of imprinted genes in humans

(2012) Miho Ishida et al.   MOLECULAR ASPECTS OF MEDICINE

Necdin Controls Proliferation of White Adipocyte Progenitor Cells

(2012) Kazushiro Fujiwara et al.   PLoS One

Postnatal Changes in the Expression Pattern of the Imprinted Signalling Protein XLαs Underlie the Changing Phenotype of Deficient Mice

(2012) Stefan O. Krechowec et al.   PLoS One

Loss of XL s (extra-large  s) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib

(2012) E. Fernandez-Rebollo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing

(2012) P. A. Latos et al.   SCIENCE

Loss of Gnas Imprinting Differentially Affects REM/NREM Sleep and Cognition in Mice

(2012) Glenda Lassi et al.   PLoS Genetics

Critical Evaluation of Imprinted Gene Expression by RNA–Seq: A New Perspective

(2012) Brian DeVeale et al.   PLoS Genetics

Genomic Imprinting: A Mammalian Epigenetic Discovery Model

(2011) Denise P. Barlow   Annual Review of Genetics

Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci

(2011) Sima J. Zacharek et al.   Cell Stem Cell

Transcription and histone methylation changes correlate with imprint acquisition in male germ cells

(2011) Amandine Henckel et al.   EMBO JOURNAL

Impaired Hypothalamic Regulation of Endocrine Function and Delayed Counterregulatory Response to Hypoglycemia inMagel2-Null Mice

(2011) Alysa A. Tennese et al.   ENDOCRINOLOGY

The Thyroid Hormone-Inactivating Type III Deiodinase Is Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Insulin Secretion

(2011) Mayrin C. Medina et al.   ENDOCRINOLOGY

Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression

(2011) Hiroaki Okae et al.   HUMAN MOLECULAR GENETICS

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

(2011) Hsien-Sung Huang et al.   NATURE

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

(2011) Alastair S. Garfield et al.   NATURE

Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis

(2011) Sacri R. Ferrón et al.   NATURE

Imprinted Genes That Regulate Early Mammalian Growth Are Coexpressed in Somatic Stem Cells

(2011) Jonathan S. Berg et al.   PLoS One

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

(2011) Y. Yu et al.   SCIENCE

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

(2011) P. P. Hsu et al.   SCIENCE

Bidirectional Control of Social Hierarchy by Synaptic Efficacy in Medial Prefrontal Cortex

(2011) F. Wang et al.   SCIENCE

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

(2011) Jessica J. Howell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

(2011) Angela M. Mabb et al.   TRENDS IN NEUROSCIENCES

Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster

(2011) Christine M. Williamson et al.   PLoS Genetics

Prader-Willi syndrome and Angelman syndrome

(2010) Karin Buiting   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Transient neonatal diabetes mellitus type 1

(2010) Deborah J.G. Mackay et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Imprinting on chromosome 20: Tissue-specific imprinting and imprinting mutations in the GNAS locus

(2010) Gavin Kelsey   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

The H19 locus: Role of an imprinted non-coding RNA in growth and development

(2010) Anne Gabory et al.   BIOESSAYS

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

A MODEL FOR GENOMIC IMPRINTING IN THE SOCIAL BRAIN: JUVENILES

(2010) Francisco Úbeda et al.   EVOLUTION

A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene

(2010) Fabienne Schaller et al.   HUMAN MOLECULAR GENETICS

Parent-Of-Origin Effects in Autism Identified through Genome-Wide Linkage Analysis of 16,000 SNPs

(2010) Delphine Fradin et al.   PLoS One

Altered Ultrasonic Vocalization and Impaired Learning and Memory in Angelman Syndrome Mouse Model with a Large Maternal Deletion from Ube3a to Gabrb3

(2010) Yong-hui Jiang et al.   PLoS One

Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

(2010) L. F. Frohlich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

(2009) Jin Nakatani et al.   CELL

Central Nervous System Imprinting of the G Protein Gsα and Its Role in Metabolic Regulation

(2009) Min Chen et al.   Cell Metabolism

The interrelationship between sleep regulation and thermoregulation

(2009) Kurt Krauchi   Frontiers in Bioscience-Landmark

Transcription is required for establishment of germline methylation marks at imprinted genes

(2009) M. Chotalia et al.   GENES & DEVELOPMENT

Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe pre- and postnatal growth retardation

(2009) Hirosuke Shiura et al.   HUMAN MOLECULAR GENETICS

A missense mutation in the non-neural G-protein α-subunit isoforms modulates susceptibility to obesity

(2009) M L Kelly et al.   INTERNATIONAL JOURNAL OF OBESITY

The role of GNAS and other imprinted genes in the development of obesity

(2009) L S Weinstein et al.   INTERNATIONAL JOURNAL OF OBESITY

Dominant rats are natural risk takers and display increased motivation for food reward

(2009) J.F. Davis et al.   NEUROSCIENCE

Gene Dosage Effects of the Imprinted Delta-Like Homologue 1 (Dlk1/Pref1) in Development: Implications for the Evolution of Imprinting

(2009) Simao Teixeira da Rocha et al.   PLoS Genetics

Huddling: Brown Fat, Genomic Imprinting and the Warm Inner Glow

(2008) David Haig   CURRENT BIOLOGY

Global Survey of Genomic Imprinting by Transcriptome Sequencing

(2008) Tomas Babak et al.   CURRENT BIOLOGY

A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10

(2008) Lionel A Sanz et al.   EMBO JOURNAL

Severe Obesity and Insulin Resistance due to Deletion of the Maternal Gsα Allele Is Reversed by Paternal Deletion of the Gsα Imprint Control Region

(2008) Tao Xie et al.   ENDOCRINOLOGY

Epigenetics, brain evolution and behaviour

(2008) Eric B. Keverne et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Physiological Dysfunctions Associated with Mutations of the Imprinted Gnas Locus

(2008) Stefan Krechowec et al.   PHYSIOLOGY

SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice

(2008) Feng Ding et al.   PLoS One

The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin

(2008) T. Nagano et al.   SCIENCE

Metabolic programming in the immediate postnatal period

(2008) Malathi Srinivasan et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genomic imprinting at the mammalian Dlk1-Dio3 domain

(2008) Simao Teixeira da Rocha et al.   TRENDS IN GENETICS