Glucose fluxes in glycolytic and oxidative pathways detected in vivo by deuterium magnetic resonance spectroscopy reflect proliferation in mouse glioblastoma

Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells

(2021) Selva Rupa Christinal Immanuel et al.   npj Systems Biology and Applications

Monitoring tumor cell death in murine tumor models using deuterium magnetic resonance spectroscopy and spectroscopic imaging

(2021) Friederike Hesse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma

(2021) Kelly J. McKelvey et al.   Frontiers in Oncology

Metabolic therapy and bioenergetic analysis: The missing piece of the puzzle

(2021) Tomás Duraj et al.   Molecular Metabolism

Metabolic reprogramming and cancer progression

(2020) Brandon Faubert et al.   SCIENCE

Phenotype stability under dynamic brain-tumor environment stimuli maps glioblastoma progression in patients

(2020) Vinodh N. Rajapakse et al.   Science Advances

The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells

(2020) Jie Li et al.   Science Signaling

Noninvasive diffusion magnetic resonance imaging of brain tumour cell size for the early detection of therapeutic response

(2020) Thomas A. Roberts et al.   Scientific Reports

The tumor microenvironment

(2020) Nicole M. Anderson et al.   CURRENT BIOLOGY

Characterization of Kinetic Isotope Effects and Label Loss in Deuterium-Based Isotopic Labeling Studies

(2020) Robin A. de Graaf et al.   ACS Chemical Neuroscience

The Suitability of Glioblastoma Cell Lines as Models for Primary Glioblastoma Cell Metabolism

(2020) Anya L. Arthurs et al.   Cancers

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma

(2019) Yufeng Shi et al.   NATURE

Reactive Oxygen Species in the Tumor Microenvironment: An Overview

(2019) Frank Weinberg et al.   Cancers

On the magnetic field dependence of deuterium metabolic imaging

(2019) Robin A. Graaf et al.   NMR IN BIOMEDICINE

Measuring Tumor Glycolytic Flux in Vivo by Using Fast Deuterium MRI

(2019) Felix Kreis et al.   RADIOLOGY

In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

(2018) Marta Lai et al.   INTERNATIONAL JOURNAL OF CANCER

An inhibitor of oxidative phosphorylation exploits cancer vulnerability

(2018) Jennifer R. Molina et al.   NATURE MEDICINE

Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo

(2018) Henk M. De Feyter et al.   Science Advances

Quantitative assessment of brain glucose metabolic rates using in vivo deuterium magnetic resonance spectroscopy

(2017) Ming Lu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Evaluation of the Response of Intracranial Xenografts to VEGF Signaling Inhibition Using Multiparametric MRI

(2017) Jessica K.R. Boult et al.   NEOPLASIA

Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer

(2017) Sangmoo Jeong et al.   Science Advances

Metabolic Plasticity as a Determinant of Tumor Growth and Metastasis

(2016) Camille Lehuédé et al.   CANCER RESEARCH

Denoising of diffusion MRI using random matrix theory

(2016) Jelle Veraart et al.   NEUROIMAGE

Sensitization of Glioblastoma Cells to Irradiation by Modulating the Glucose Metabolism

(2015) H. Shen et al.   MOLECULAR CANCER THERAPEUTICS

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment

(2015) Rui V. Simões et al.   NEOPLASIA

Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects

(2014) T. T. Batchelor et al.   CLINICAL CANCER RESEARCH

Immunocompetent murine models for the study of glioblastoma immunotherapy

(2014) Taemin Oh et al.   Journal of Translational Medicine

Targeting adaptive glioblastoma: an overview of proliferation and invasion

(2014) Q. Xie et al.   NEURO-ONCOLOGY

DCE@urLAB: a dynamic contrast-enhanced MRI pharmacokinetic analysis tool for preclinical data

(2013) Juan E Ortuño et al.   BMC BIOINFORMATICS

Analysis of Tumor Metabolism Reveals Mitochondrial Glucose Oxidation in Genetically Diverse Human Glioblastomas in the Mouse Brain In Vivo

(2012) Isaac Marin-Valencia et al.   Cell Metabolism

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas

(2012) Changho Choi et al.   NATURE MEDICINE

Metabolism of [U-13C]glucose in human brain tumorsin vivo

(2012) Elizabeth A. Maher et al.   NMR IN BIOMEDICINE

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

Quantitation of glucose uptake in tumors by dynamic FDG-PET has less glucose bias and lower variability when adjusted for partial saturation of glucose transport

(2012) Simon-Peter Williams et al.   EJNMMI Research

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

In vivo 13C magnetic resonance spectroscopy of a human brain tumor after application of 13C-1-enriched glucose

(2010) Jannie P. Wijnen et al.   MAGNETIC RESONANCE IMAGING

Metabolic Modulation of Glioblastoma with Dichloroacetate

(2010) E. D. Michelakis et al.   Science Translational Medicine

Quantitation of magnetic resonance spectroscopy signals: the jMRUI software package

(2009) D Stefan et al.   MEASUREMENT SCIENCE and TECHNOLOGY

Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer

(2008) Michael A. Kiebish et al.   JOURNAL OF LIPID RESEARCH

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Perturbation of mouse glioma MRS pattern by induced acute hyperglycemia

(2007) R. V. Simões et al.   NMR IN BIOMEDICINE