Roles of reactive oxygen species, mitochondrial membrane potential, and p53 in evodiamine-induced apoptosis and G2/M arrest of human anaplastic thyroid carcinoma cells

Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes

(2020) Jiawei Zhu et al.   Scientific Reports

Activation of PERK Contributes to Apoptosis and G2/M Arrest by Microtubule Disruptors in Human Colorectal Carcinoma Cells

(2020) Ming-Shun Wu et al.   Cancers

Novel treatments for anaplastic thyroid carcinoma

(2020) Silvia Martina Ferrari et al.   Gland Surgery

Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer

(2019) Matthieu Lacroix et al.   Molecular Metabolism

Evodiamine, a Novel NOTCH3 Methylation Stimulator, Significantly Suppresses Lung Carcinogenesis in Vitro and in Vivo

(2018) Tao Su et al.   Frontiers in Pharmacology

Loss of p53 expression in cancer cells alters cell cycle response after inhibition of exportin-1 but does not prevent cell death

(2018) Joshua M. Marcus et al.   CELL CYCLE

CDK4 inhibition diminishes p53 activation by MDM2 antagonists

(2018) Anusha Sriraman et al.   Cell Death & Disease

Inhibitors of cyclin-dependent kinases as cancer therapeutics

(2017) Steven R. Whittaker et al.   PHARMACOLOGY & THERAPEUTICS

Patterns of Treatment Failure in Anaplastic Thyroid Carcinoma

(2017) Sarika N. Rao et al.   THYROID

Exploiting the p53 Pathway for Therapy

(2017) Chit Fang Cheok et al.   Cold Spring Harbor Perspectives in Medicine

Evodiamine inhibits PDGF-BB-induced proliferation of rat vascular smooth muscle cells through the suppression of cell cycle progression and oxidative stress

(2016) Xie Ge et al.   Molecular Medicine Reports

Evodiamine from Evodia rutaecarpa induces apoptosis via activation of JNK and PERK in human ovarian cancer cells

(2016) Tze-Chien Chen et al.   PHYTOMEDICINE

Protein Kinase RNA-Like Endoplasmic Reticulum Kinase-Mediated Bcl-2 Protein Phosphorylation Contributes to Evodiamine-Induced Apoptosis of Human Renal Cell Carcinoma Cells

(2016) Wen-Shin Wu et al.   PLoS One

Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules

(2015) Yu Yu et al.   CANCER CELL

Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells

(2015) Bo Li et al.   CANCER LETTERS

Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors

(2015) Nawal Bendris et al.   CELL CYCLE

Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand

(2015) Venu Saralamma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Senescence and apoptosis: dueling or complementary cell fates?

(2014) B. G. Childs et al.   EMBO REPORTS

Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages

(2014) Liang-Yo Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

How Taxol/paclitaxel kills cancer cells

(2014) Beth A. Weaver   MOLECULAR BIOLOGY OF THE CELL

Evodiamine Inhibits Insulin-Stimulated mTOR-S6K Activation and IRS1 Serine Phosphorylation in Adipocytes and Improves Glucose Tolerance in Obese/Diabetic Mice

(2014) Ting Wang et al.   PLoS One

Activation of JNK Contributes to Evodiamine-Induced Apoptosis and G2/M Arrest in Human Colorectal Carcinoma Cells: A Structure-Activity Study of Evodiamine

(2014) Chih-Chiang Chien et al.   PLoS One

Evodiamine Induces G2/M Arrest and Apoptosis via Mitochondrial and Endoplasmic Reticulum Pathways in H446 and H1688 Human Small-Cell Lung Cancer Cells

(2014) Chunshu Fang et al.   PLoS One

Apoptosis and Molecular Targeting Therapy in Cancer

(2014) Mohamed Hassan et al.   Biomed Research International

Quercetin Induces Mitochondrial Mediated Apoptosis and Protective Autophagy in Human Glioblastoma U373MG Cells

(2013) Hyeonji Kim et al.   Oxidative Medicine and Cellular Longevity

P53 and its molecular basis to chemoresistance in breast cancer

(2012) Stian Knappskog et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells

(2010) Chun Zhang et al.   ANTI-CANCER DRUGS

Evodiamine: A Novel Anti-Cancer Alkaloid from Evodia rutaecarpa

(2009) Junlin Jiang et al.   MOLECULES