Article
Public, Environmental & Occupational Health
Mohammad Javad Zare Sakhvidi, Navid Danaei, Payam Dadvand, Amir Houshang Mehrparvar, Motahar Heidari-Beni, Shamsollah Nouripour, Habib Nikukar, Seyede Shahrbanoo Daniali, Elham Saffarieh, Mahmood Noorishadkam, Mohammad Mehdi Amin, Majid Mirmohammadkhani, Mohammad Hassan Lotfi, Ahmad Vaez, Seyyed Jalil Mirmohammadi, Elaheh Zarean, Mahdieh Mojibian, Mahin Hashemipour, Omid Yaghini, Mohammad Sadegh Rezai, Ali Esmaeili, Alireza Fahimzad, Hamid Hakimi, Mohammad Reza Navaeifar, Hamid Ostad Ebrahimi, Hossein Poustchi, Reza Malekzadeh, Roya Kelishadi
Summary: The PERSIAN birth cohort study in Iran aims to evaluate the associations between socio-economic characteristics, lifestyle, diet, environmental exposures, and epigenetic factors with various outcomes related to pregnancy, maternal and child health, child neurodevelopment, and chronic disease risk factors. The study plans to recruit 15,000 mother-offspring pairs and follow them for at least ten years, collecting data through three phases from periconception to childhood, including biological samples and growth monitoring. Appropriate data analysis schemes will be employed for assessing early life factors in health and disease for international comparisons.
LONGITUDINAL AND LIFE COURSE STUDIES
(2021)
Article
Immunology
Zohreh Rostami, Giuseppe Mastrangelo, Behzad Einollahi, Eghlim Nemati, Sepehr Shafiee, Mehrdad Ebrahimi, Mohammad Javanbakht, Seyed Hassan Saadat, Manouchehr Amini, Zahra Einollahi, Bentolhoda Beyram, Luca Cegolon
Summary: This study aimed to estimate the prevalence of acute kidney injury (AKI) in hospitalized COVID-19 patients and investigate the influence of clinical information and laboratory findings on AKI incidence and mortality. The study found that diabetes, hyperkalemia, higher levels of WBC count, and blood urea nitrogen (BUN) increased the incidence of AKI, while a joint association of severe/mild/moderate COVID-19 with ICU admission, hypokalemia, and higher levels of BUN, WBC, and LDH measured at hospital admission were associated with increased mortality risk in hospitalized COVID-19 patients.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Roswitha Siener, Albrecht Hesse
Summary: The study investigated the effect of black tea consumption on urinary risk factors for kidney stone formation, and found that in normal subjects, black tea intake did not significantly increase the risk of kidney stone formation. Additionally, black tea consumption did not significantly alter 24-h urinary oxalate excretion, but led to a significant increase in urinary citrate, an important inhibitor of calcium stone formation.
Review
Oncology
Saverio Caini, Sofia Chioccioli, Elisa Pastore, Miriam Fontana, Katia Tortora, Giovanna Caderni, Giovanna Masala
Summary: This study conducted a meta-analysis to investigate the association between fish consumption and colorectal cancer (CRC) risk, and found that increased fish consumption may protect against CRC development. Preclinical studies also identified multiple mechanisms through which fish components can inhibit colorectal carcinogenesis. These findings have important implications for dietary recommendations for cancer prevention.
Article
Urology & Nephrology
Megan Prochaska, John Asplin, Arlene Chapman, Elaine Worcester
Summary: The study found that men had higher calcium oxalate supersaturation in urine before RYGB, while women had higher urine calcium oxalate supersaturation and calcium phosphate supersaturation, as well as lower urine volumes after RYGB.
AMERICAN JOURNAL OF NEPHROLOGY
(2021)
Article
Urology & Nephrology
Kai Wang, Jing Ge, Wenlong Han, Dong Wang, Yinjuan Zhao, Yanhao Shen, Jiexun Chen, Dongming Chen, Jing Wu, Ning Shen, Shuai Zhu, Bin Xue, Xianlin Xu
Summary: This meta-analysis identified 12 risk factors related to the recurrence of kidney stone disease, including younger age, higher BMI, family history, personal history, hypertension, uric acid stone, and others. Patients with higher BMI, personal history of nephrolithiasis, or surgery history were found to have a higher risk of radiographic kidney stone disease recurrence.
Article
Medicine, General & Internal
Si-Yu Long, Ji-Ya Sun, Le Wang, Heng Long, Hai-Qin Jiang, Ying Shi, Wen-Yue Zhang, Jing-Shu Xiong, Pei-Wen Sun, Yan-Qing Chen, You-Ming Mei, Chun Pan, Zhen-Zhen Wang, Zi-Wei Wu, Ai-Ping Wu, Mei-Wen Yu, Hong-Sheng Wang
Summary: The study established a predictive model for leprosy risk using genetic and epidemiological factors among household contacts, achieving high accuracy and effectiveness in predicting leprosy risk among these contacts.
Article
Microbiology
Naveen Kachroo, Dirk Lange, Kristina L. Penniston, Joshua Stern, Gregory Tasian, Petar Bajic, Alan J. Wolfe, Mangesh Suryavanshi, Andrea Ticinesi, Tiziana Meschi, Manoj Monga, Aaron W. Miller
Summary: This research investigated whether questions related to the urinary or gut microbiome and urinary stone disease (USD) can be answered through metagenome-wide association studies (MWAS). The study found significant differences in microbiome composition based on factors like USD status, stone composition, age group, and study location. Results indicate the importance of standardizing experimental protocols in the field to assess microbiome differences accurately.
Article
Biochemistry & Molecular Biology
Andreea Andronesi, Bogdan Sorohan, Andreea Burcea, Lavinia Lipan, Cristina Stanescu, Oana Craciun, Laura Stefan, Adela Ranete, Zsofia Varady, Oana Ungureanu, Gabriela Lupusoru, Gabriela Agrigoroaei, Danut Andronesi, Luminita Iliuta, Bogdan Obrisca, Alina Tanase
Summary: AKI is a common and serious complication after allo-HSCT. Monitoring of calcineurin inhibitors and proper management of sepsis are important in reducing the risk of developing AKI.
Review
Nutrition & Dietetics
Evangelia Damigou, Rena I. Kosti, Demosthenes B. Panagiotakos
Summary: This study analyzed the relationship between white meat consumption and cardiometabolic risk factors and found that consuming fresh lean white meat may have potential beneficial effects on these risk factors. However, there are still controversial findings in existing studies, and future research should further investigate the association between white meat consumption habits and cardiometabolic risk factors.
Review
Oncology
Bayan Hosseini, Amy L. Hall, Kazem Zendehdel, Hans Kromhout, Felix M. Onyije, Rahmatollah Moradzadeh, Maryam Zamanian, Joachim Schuz, Ann Olsson
Summary: Occupational cancers in Iran are still in an early stage of epidemiology. Studies on exposure monitoring and epidemiology are limited in size, thus unable to provide strong evidence of occupational cancer risks. It is necessary to estimate the burden of occupational cancer in Iran through conducting epidemiological studies and systematically monitoring occupational carcinogens.
Article
Infectious Diseases
Seyed Mohammad Hashemi-Shahri, Seyed Mohammad Nasiraldin Tabatabaei, Alireza Ansari-Moghaddam, Mahdi Mohammadi, Hassan Okati-Aliabad, Seyed Mehdi Tabatabaei, Hossein Ansari, Mohammadhadi Abbasi, Khodadad Sheikhzadeh, Mehdi Zanganeh Baygi, Majid Sartipi, Sharareh Sanei-Sistani, Ali Reza Salimi Khorashad, Fatemeh Ansari-Moghadam, Neda Torab, Tahereh Khalili, Ghasem Miri-Aliabad
Summary: This study investigated the epidemiological and clinical features of COVID-19 in a less privileged area in Iran and found that older age, a history of substance abuse, and underlying diseases were associated with increased severity of the disease.
BMC INFECTIOUS DISEASES
(2022)
Article
Nutrition & Dietetics
Roswitha Siener, Charlotte Ernsten, Norman Bitterlich, Birgit Alteheld, Christine Metzner
Summary: Weight reduction can decrease the risk of kidney stone formation, and an energy-restricted modified diet with meal replacement shows better outcomes.
Review
Cell Biology
Qiao Jin, Ronald Ching Wan Ma
Summary: Metabolomics plays a crucial role in the study of diabetes and its complications, enabling the identification of biomarkers, deepening molecular understanding, identifying therapeutic targets, and improving prevention and management strategies.
Article
Urology & Nephrology
Leila Moftakhar, Fatemeh Jafari, Masoumeh Ghoddusi Johari, Ramin Rezaeianzadeh, Seyed Vahid Hosseini, Abbas Rezaianzadeh
Summary: This study investigated the prevalence and risk factors of kidney stone in the adult population of southern Iran. The results identified fatty liver, diabetes, hypertension, as well as age, male sex, overweight, and high social economic status as important risk factors for kidney stone.
Article
Endocrinology & Metabolism
Mojgan Noroozi Karimabad, Parvin Khalili, Fatemeh Ayoobi, Ali Esmaeili-Nadimi, Carlo La Vecchia, Zahra Jamali
Summary: Elevated levels of ALT, AST, GGT, and ALP are associated with a higher odds of diabetes. Additionally, increased levels of ALT, GGT, and ALP even within the normal range are independently associated with an increased odds of diabetes.
BMC ENDOCRINE DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Parvin Khalili, Saeedeh Abdollahpoor, Fatemeh Ayoobi, Alireza Vakilian, Hamid Hakimi, Zohreh Rajabi, Zahra Jamali
Summary: This study aimed to evaluate the relationship between liver enzymes (ALT, AST, GGT, and ALP) and hypertension. The results showed that increased serum ALP activity was positively associated with increased odds of hypertension in subjects with normal levels of liver enzymes.
INTERNATIONAL JOURNAL OF HYPERTENSION
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mehrad Rafiei, Somayeh Salarisedigh, Parvin Khalili, Zahra Jamali, Farimah Sardari
Summary: This study aimed to evaluate the correlation between hormonal fluctuations and periodontal status in postmenopausal women. Data from the Rafsanjan Cohort Study (RCS) was analyzed, and it was found that there was no correlation between hormonal fluctuations and periodontal status.
INTERNATIONAL JOURNAL OF DENTISTRY
(2022)
Article
Multidisciplinary Sciences
Hajar Vatankhah, Parvin Khalili, Mahboubeh Vatanparast, Fatemeh Ayoobi, Ali Esmaeili-Nadimi, Zahra Jamali
Summary: The study aimed to evaluate the prevalence of early and late menopause and its determinants in adult women. Data from Rafsanjan Cohort Study was used and 2002 postmenopausal women were included. The results showed that factors such as height, smoking, history of hormonal contraceptive use, diabetes, hypertension, thyroid disease, and depression were significantly associated with menopausal age. Understanding the determinants of menopausal age is important for women's subsequent health.
SCIENTIFIC REPORTS
(2023)
Article
Endocrinology & Metabolism
Mohammadreza Soleimani, Fateme Alipour, Yousef Taghavi, Marjan Fatemipour, Hamid Hakimi, Zahra Jamali, Parvin Khalili, Fatemeh Ayoobi, Maryam Sheikh, Roya Tavakoli, Amin Zand
Summary: We determined the prevalence and risk factors for diabetic retinopathy (DR) in Rafsanjan City, Iran using single-field fundus photographs. Duration of diabetes, positive family history for diabetes, fasting plasma glucose, and serum creatinine level may be associated with DR.
Article
Public, Environmental & Occupational Health
Tabandeh Sadeghi, Narjes Soltani, Zahra Jamali, Fatemeh Ayoobi, Parvin Khalili, Ali Shamsizadeh, Mostafa Nasirzadeh, Ali Esmaeili-Nadimi, Carlo La Vecchia, Zahra Jalali
Summary: This study aimed to determine the association of demographic and lifestyle parameters with overweight/obesity and abdominal obesity in a population of Iranian adults. The results recommend local public health strategies that promote training the society on the health benefits of avoiding alcohol, getting more physical exercise, and gaining more personal education on the health-threatening lifestyle.
Article
Endocrinology & Metabolism
Amir Moghadam-Ahmadi, Narjes Soltani, Fatemeh Ayoobi, Zahra Jamali, Tabandeh Sadeghi, Nazanin Jalali, Alireza Vakilian, Mohammad Amin Lotfi, Parvin Khalili
Summary: This study aimed to assess the prevalence of metabolic syndrome (MetS) among adults and its association with stroke. The results showed a significant correlation between MetS and increased risk of stroke. Therefore, early detection, treatment, and prevention of metabolic syndrome are of great importance.
BMC ENDOCRINE DISORDERS
(2023)
Article
Endocrinology & Metabolism
Majid Kazemi, Parvin Khalili, Mahsa Kazemi, Hadi Hasani, Marjan Sadeghi, Zahra Jamali
Summary: This study aimed to investigate the relationship between sleep-related parameters and metabolic syndrome (MetS) among youths in Rafsanjan, Iran. The findings showed that long sleep duration at night was associated with a lower risk of central obesity.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Article
Multidisciplinary Sciences
Morteza Khademalhosseini, Elham Ranjbar, Rezvan Mohammadi, Parvin Khalili, Mahya Mehran, Nazanin Jalali, Zohreh Rajabi, Zahra Jamali
Summary: Oxidative stress is the main contributor to liver injury, and dietary antioxidants are expected to improve liver function. This study found that higher consumption of selenium (Se), vitamin A, vitamin E, and provitamin A carotenoids (beta-carotene, alpha-carotene, beta-cryptoxanthin) is associated with a decreased risk of elevated alkaline phosphatase (ALP) levels.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Nazanin Jalali, Parvin Khalili, Zahra Jamali, Zahra Jalali, Amir Moghadam-Ahmadi, Alireza Vakilian, Fatemeh Ayoobi
Summary: This study found that both short and long sleep durations are associated with demographic, medication use, personal habits, and chronic diseases. The impact of hypnotic drug use on sleep duration was also considered. The results showed that short sleep duration was significantly associated with age, BMI, physical activity, and depression, while long sleep duration was associated with female sex, opium consumption, and history of MI. Stratified analysis for hypnotic drug use revealed additional associations with education, physical activity, opium consumption, and thyroid dysfunction.
SCIENTIFIC REPORTS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Parvin Khalili, Atekeh Movagharipoor, Farimah Sardari, Fatemeh Movaghari Pour, Zahra Jamali
Summary: This study investigated the association between oral candidiasis prevalence and cigarette, tobacco, alcohol, and opium consumption in Rafsanjan, Iran. The results showed a direct association between smoking and alcohol consumption with oral candidiasis.
Article
Immunology
Pedram Basirjafar, Raziyeh Zandvakili, Javad Masoumi, Nahid Zainodini, Zahra Taghipour, Hossein Khorramdelazad, Soheila Yousefi, Tayyebeh Tavakoli, Mahboobeh Vatanparast, Sepehr Safdel, Mahsa Gheitasi, Fatemeh Ayoobi, Bahar Naseri, Abdollah Jafarzadeh
Summary: The study found that the Leptin/LPS-treated mDC vaccine was more effective in inhibiting breast cancer development and boosting immune responses, by increasing CTLs and TH1 cells frequency, promoting IFN-gamma and IL-12 production, as well as enhancing T-bet and Granzyme B expression.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Fatemeh Ayoobi, Somaye Salari Sedigh, Parvin Khalili, Zeinab Sharifi, Hamid Hakimi, Farimah Sardari, Zahra Jamali
Summary: This study aimed to determine the association between dyslipidemia, diabetes and periodontal disease. The results showed that high total cholesterol, high LDL cholesterol, diabetes, and having both dyslipidemia and diabetes were all associated with an increased odds of periodontal disease.
Article
Medical Laboratory Technology
Ali Esmaeili-Nadimi, Fatemeh Imanparast, Samira Alizadeh, Akram Vatannejad, Pegah Mohaghegh, Seyed M. Seyedmehdi, Carlo La Vecchia, Zahra Jamali
Summary: This study investigated the relationship between total antioxidant capacity (TAC), total oxidant status (TOS), TAC/TOS levels, and disease severity in hospitalized patients with COVID-19. The results showed no significant difference in serum levels of TAC, TOS, and TAC/TOS in terms of disease severity.
CLINICAL LABORATORY
(2023)
