Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer

Inhibition of apelin/APJ axis enhances the potential of dendritic cell-based vaccination to modulate TH1 and TH2 cell-related immune responses in an animal model of metastatic breast cancer

(2022) Javad Masoumi et al.   Advances in Medical Sciences

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ex vivo dendritic cell-based (DC) vaccine pulsed with a low dose of liposomal antigen and CpG-ODN improved PD-1 blockade immunotherapy

(2021) Mona Yazdani et al.   Scientific Reports

Murine Dendritic Cells Grown in Serum-Free Culture Show Potent Therapeutic Activity when Loaded with Novel Th Epitopes in an Orthotopic Model of HER2pos Breast Cancer

(2021) Loral E. Showalter et al.   Vaccines

Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine

(2021) Amrita Basu et al.   Cancer Immunology Research

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

(2020) Yuanyuan Zhang et al.   Cellular & Molecular Immunology

Investigation of the combination of anti-PD-L1 mAb with HER2/neu-loaded dendritic cells and QS-21 saponin adjuvant: effect against HER2 positive breast cancer in mice

(2020) Cenk Serhan Özverel et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen

(2019) Stefanie K. Wculek et al.   Journal for ImmunoTherapy of Cancer

An efficient or methodical review of immunotherapy against breast cancer

(2019) Ren Guanghui et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Personalized Dendritic Cell Vaccines—Recent Breakthroughs and Encouraging Clinical Results

(2019) Beatris Mastelic-Gavillet et al.   Frontiers in Immunology

Functional Relationship between Leptin and Nitric Oxide in Metabolism

(2019) Sara Becerril et al.   Nutrients

Personalized neoantigen-pulsed dendritic cell vaccines show superior immunogenicity to neoantigen-adjuvant vaccines in mouse tumor models

(2019) Rui Zhang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Single Cell Mass Cytometry Revealed the Immunomodulatory Effect of Cisplatin Via Downregulation of Splenic CD44+, IL-17A+ MDSCs and Promotion of Circulating IFN-γ+ Myeloid Cells in the 4T1 Metastatic Breast Cancer Model

(2019) József Á. Balog et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adipokines and inflammation: is it a question of weight?

(2018) Vera Francisco et al.   BRITISH JOURNAL OF PHARMACOLOGY

T cell subsets play an important role in the determination of the clinical outcome of Helicobacter pylori infection

(2018) Abdollah Jafarzadeh et al.   MICROBIAL PATHOGENESIS

Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer

(2018) Lina Liu et al.   MOLECULAR THERAPY

An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells

(2018) Michele Tomasicchio et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CD73 specific siRNA loaded chitosan lactate nanoparticles potentiate the antitumor effect of a dendritic cell vaccine in 4T1 breast cancer bearing mice

(2017) Farhad Jadidi-Niaragh et al.   JOURNAL OF CONTROLLED RELEASE

Microwave ablation combined with OK-432 induces Th1-type response and specific antitumor immunity in a murine model of breast cancer

(2017) Li Li et al.   Journal of Translational Medicine

Time-dependent effect of E. coli LPS in spleen DC activation in vivo : Alteration of numbers, expression of co-stimulatory molecules, production of pro-inflammatory cytokines, and presentation of antigens

(2017) Li Xu et al.   MOLECULAR IMMUNOLOGY

Leptin in the interplay of inflammation, metabolism and immune system disorders

(2017) Vanessa Abella et al.   Nature Reviews Rheumatology

Elevated level of pro inflammatory cytokine and chemokine expression in chicken bone marrow and monocyte derived dendritic cells following LPS induced maturation

(2016) Semmannan Kalaiyarasu et al.   CYTOKINE

Leptin Regulation of Immune Responses

(2016) Caitlin Naylor et al.   TRENDS IN MOLECULAR MEDICINE

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

(2015) Itay Raphael et al.   CYTOKINE

Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells

(2013) Pedro M.M. Moraes-Vieira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4+ follicular helper T cell infiltration predicts breast cancer survival

(2013) Chunyan Gu-Trantien et al.   JOURNAL OF CLINICAL INVESTIGATION

Leptin Metabolically Licenses T Cells for Activation To Link Nutrition and Immunity

(2013) D. C. Saucillo et al.   JOURNAL OF IMMUNOLOGY

Impact of anti-CD25 monoclonal antibody on dendritic cell-tumor fusion vaccine efficacy in a murine melanoma model

(2013) Chunrui Tan et al.   Journal of Translational Medicine

Leptin-based adjuvants: An innovative approach to improve vaccine response

(2013) Sarah J. White et al.   VACCINE

Autologous dendritic cell vaccine for estrogen receptor (ER)/progestin receptor (PR) double-negative breast cancer

(2012) Chun-Jian Qi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Hydrodynamic cell delivery for simultaneous establishment of tumor growth in mouse lung, liver and kidney

(2011) Jianfeng Li et al.   CANCER BIOLOGY & THERAPY

Leptin as an immunomodulator

(2011) Claudio Procaccini et al.   MOLECULAR ASPECTS OF MEDICINE

Optimizing DC Vaccination by Combination With Oncolytic Adenovirus Coexpressing IL-12 and GM-CSF

(2011) Song-Nan Zhang et al.   MOLECULAR THERAPY

Role of Leptin in the Activation of Immune Cells

(2010) Patricia Fernández-Riejos et al.   MEDIATORS OF INFLAMMATION

Leptin: A Critical Regulator of CD4+T-cell Polarizationin Vitroandin Vivo

(2009) Arvind Batra et al.   ENDOCRINOLOGY

Leptin as an immunological adjuvant: enhanced migratory and CD8+ T cell stimulatory capacity of human dendritic cells exposed to leptin

(2008) Benedetta Mattioli et al.   FASEB JOURNAL