Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength
出版年份 2022 全文链接
标题
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength
作者
关键词
-
出版物
Nature Communications
Volume 13, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-02-16
DOI
10.1038/s41467-022-28557-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mitochondrial LonP1 protease is implicated in the degradation of unstable Parkinson's disease-associated DJ-1/PARK 7 missense mutants
- (2021) Raúl Sánchez-Lanzas et al. Scientific Reports
- Mitochondrial Proteases: Multifaceted Regulators of Mitochondrial Plasticity
- (2020) Soni Deshwal et al. Annual Review of Biochemistry
- Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals
- (2020) Jessica Segalés et al. Nature Communications
- Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction
- (2020) Lin Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- LonP1 regulates mitochondrial network remodeling through the PINK1/Parkin pathway during myoblast differentiation
- (2020) Shiyuan Huang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Quality control of the mitochondrial proteome
- (2020) Jiyao Song et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitocellular communication: Shaping health and disease
- (2019) Adrienne Mottis et al. SCIENCE
- PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5
- (2018) Dae-Hee Lee et al. Autophagy
- Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency
- (2018) Aida Rodríguez‐Nuevo et al. EMBO JOURNAL
- CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis
- (2018) Christina Becker et al. EMBO REPORTS
- Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity
- (2018) Tingting Fu et al. Cell Reports
- Skeletal muscle mitochondrial remodeling in exercise and diseases
- (2018) Zhenji Gan et al. CELL RESEARCH
- Mitochondrial fission facilitates the selective mitophagy of protein aggregates
- (2017) Jonathon L. Burman et al. JOURNAL OF CELL BIOLOGY
- Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy
- (2017) Rebecca J. Wilson et al. MITOCHONDRION
- Acute rotator cuff tears
- (2017) Richard Craig et al. BMJ-British Medical Journal
- Acute rotator cuff tears
- (2017) Richard Craig et al. BMJ-British Medical Journal
- Exercise Promotes Healthy Aging of Skeletal Muscle
- (2016) Gregory D. Cartee et al. Cell Metabolism
- Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway
- (2016) David Sebastián et al. EMBO JOURNAL
- Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit
- (2016) Jing Liu et al. EMBO Molecular Medicine
- Mitonuclear communication in homeostasis and stress
- (2016) Pedro M. Quirós et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- CODAS Syndrome Is Associated with Mutations of LONP1, Encoding Mitochondrial AAA+ Lon Protease
- (2015) Kevin A. Strauss et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Muscle as a “Mediator” of Systemic Metabolism
- (2015) Kedryn K. Baskin et al. Cell Metabolism
- The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage
- (2015) Tatiana Varanita et al. Cell Metabolism
- Opa1 Overexpression Ameliorates the Phenotype of Two Mitochondrial Disease Mouse Models
- (2015) Gabriele Civiletto et al. Cell Metabolism
- The role of mTOR signaling in the regulation of protein synthesis and muscle mass during immobilization in mice
- (2015) Jae-Sung You et al. Disease Models & Mechanisms
- Measuring In Vivo Mitophagy
- (2015) Nuo Sun et al. MOLECULAR CELL
- Muscle wasting in disease: molecular mechanisms and promising therapies
- (2015) Shenhav Cohen et al. NATURE REVIEWS DRUG DISCOVERY
- New roles for mitochondrial proteases in health, ageing and disease
- (2015) Pedro M. Quirós et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins
- (2015) Sarah E. Calvo et al. NUCLEIC ACIDS RESEARCH
- PGC-1α modulates denervation-induced mitophagy in skeletal muscle
- (2015) Anna Vainshtein et al. Skeletal Muscle
- LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins
- (2015) Ayenachew Bezawork-Geleta et al. Scientific Reports
- ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity
- (2014) Pedro M. Quirós et al. Cell Reports
- Skeletal muscle atrophy during short-term disuse: Implications for age-related sarcopenia
- (2013) Benjamin T. Wall et al. AGEING RESEARCH REVIEWS
- The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
- (2013) Seok Min Jin et al. Autophagy
- Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy
- (2013) Perrine Castets et al. Cell Metabolism
- Signaling pathways controlling skeletal muscle mass
- (2013) Marc A. Egerman et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Skeletal muscle autophagy: a new metabolic regulator
- (2013) Brian A. Neel et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle
- (2012) Michael F. O'Leary et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives
- (2012) S. H. Bernstein et al. BLOOD
- DJ-1 Protects Dopaminergic Neurons against Rotenone-Induced Apoptosis by Enhancing ERK-Dependent Mitophagy
- (2012) H. Gao et al. JOURNAL OF MOLECULAR BIOLOGY
- Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease
- (2012) Bin Lu et al. MOLECULAR CELL
- Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice
- (2012) V. Moresi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Mechanisms and Treatment Options for Muscle Wasting Diseases
- (2011) Markus A. Rüegg et al. Annual Review of Pharmacology and Toxicology
- The nuclear receptor PPAR / programs muscle glucose metabolism in cooperation with AMPK and MEF2
- (2011) Z. Gan et al. GENES & DEVELOPMENT
- Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6
- (2011) D. Quiat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations
- (2010) Hsiuchen Chen et al. CELL
- Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases
- (2010) Viviana Moresi et al. CELL
- Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity
- (2010) Christoph Zechner et al. Cell Metabolism
- Autophagy Is Required to Maintain Muscle Mass
- (2009) Eva Masiero et al. Cell Metabolism
- SUnSET, a nonradioactive method to monitor protein synthesis
- (2009) Enrico K Schmidt et al. NATURE METHODS
- Rotator-Cuff Failure
- (2008) Frederick A. Matsen NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now