Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies

Structural insights into RNA polymerases of negative-sense RNA viruses

(2021) Aartjan J. W. te Velthuis et al.   NATURE REVIEWS MICROBIOLOGY

Influenza Therapeutics in Clinical Practice—Challenges and Recent Advances

(2020) John H. Beigel et al.   Cold Spring Harbor Perspectives in Medicine

A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase

(2020) Joanna M. Wandzik et al.   CELL

Structure and Function of Influenza Polymerase

(2020) Joanna M. Wandzik et al.   Cold Spring Harbor Perspectives in Medicine

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Host ANP32A mediates the assembly of the influenza virus replicase

(2020) Loïc Carrique et al.   NATURE

Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction

(2020) Ali Punjani et al.   NATURE METHODS

Interplay between Influenza Virus and the Host RNA Polymerase II Transcriptional Machinery

(2019) Alexander P. Walker et al.   TRENDS IN MICROBIOLOGY

Structural snapshots of actively transcribing influenza polymerase

(2019) Tomas Kouba et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insight into RNA synthesis by influenza D polymerase

(2019) Qi Peng et al.   Nature Microbiology

Structures of influenza A virus RNA polymerase offer insight into viral genome replication

(2019) Haitian Fan et al.   NATURE

Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region

(2019) David C. McGowan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Current Developments in Coot for Macromolecular Model Building of Electron Cryo‐microscopy and Crystallographic Data

(2019) Ana Casañal et al.   PROTEIN SCIENCE

Priming and realignment by the influenza a virus RdRp is dependent on the length of the host primers and the extent of base pairing to viral RNA

(2019) Corey De Vlugt et al.   VIROLOGY

Structure and Function of the Influenza Virus Transcription and Replication Machinery

(2019) Ervin Fodor et al.   Cold Spring Harbor Perspectives in Medicine

A Mechanism for the Activation of the Influenza Virus Transcriptase

(2018) Itziar Serna Martin et al.   MOLECULAR CELL

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

MolProbity: More and better reference data for improved all-atom structure validation

(2017) Christopher J. Williams et al.   PROTEIN SCIENCE

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human Cells

(2016) Benjamin Mänz et al.   JOURNAL OF VIROLOGY

RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II

(2016) Mónica Martínez-Alonso et al.   JOURNAL OF VIROLOGY

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains

(2016) Eric Thierry et al.   MOLECULAR CELL

Structural basis of an essential interaction between influenza polymerase and Pol II CTD

(2016) Maria Lukarska et al.   NATURE

The role of the priming loop in influenza A virus RNA synthesis

(2016) Aartjan J. W. te Velthuis et al.   Nature Microbiology

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus

(2015) Narin Hengrung et al.   NATURE

Sequencing the cap-snatching repertoire of H1N1 influenza provides insight into the mechanism of viral transcription initiation

(2015) David Koppstein et al.   NUCLEIC ACIDS RESEARCH

Influenza A virus preferentially snatches noncoding RNA caps

(2015) Weifeng Gu et al.   RNA

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

(2014) Stefan Reich et al.   NATURE

Structure of influenza A polymerase bound to the viral RNA promoter

(2014) Alexander Pflug et al.   NATURE

A general protocol for the generation of Nanobodies for structural biology

(2014) Els Pardon et al.   Nature Protocols

At the centre: influenza A virus ribonucleoproteins

(2014) Amie J. Eisfeld et al.   NATURE REVIEWS MICROBIOLOGY

Characterization of the Noncoding Regions of the 1918 Influenza A H1N1 Virus

(2013) R. Wang et al.   JOURNAL OF VIROLOGY

Isolation and characterization of the positive-sense replicative intermediate of a negative-strand RNA virus

(2013) A. York et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Data processing and analysis with theautoPROCtoolbox

(2011) Clemens Vonrhein et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The N-Terminal Region of the PA Subunit of the RNA Polymerase of Influenza A/HongKong/156/97 (H5N1) Influences Promoter Binding

(2009) Takahito Kashiwagi et al.   PLoS One