Strategies to package recombinant Adeno-Associated Virus expressing the N-terminal gasdermin domain for tumor treatment

The nf-core framework for community-curated bioinformatics pipelines

(2020) Philip A. Ewels et al.   NATURE BIOTECHNOLOGY

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

(2020) Zhibin Zhang et al.   NATURE

A bioorthogonal system reveals antitumour immune function of pyroptosis

(2020) Qinyang Wang et al.   NATURE

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

PD-1/PD-L1 pathway: Basic biology and role in cancer immunotherapy

(2019) Arash Salmaninejad et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting Tumor Microenvironment for Cancer Therapy

(2019) Catarina Roma-Rodrigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

(2019) Denarda Dangaj et al.   CANCER CELL

Red blood cell–derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy

(2019) Xiao Han et al.   Science Advances

The anatomy and metabolome of the lymphatic system in the brain in health and disease

(2019) Wenbo He et al.   BRAIN PATHOLOGY

T Cell Dysfunction in Cancer

(2018) Daniela S. Thommen et al.   CANCER CELL

Promoter-Operating Targeted Expression of Gene Therapy in Cancer: Current Stage and Prospect

(2018) Chao Chen et al.   Molecular Therapy-Nucleic Acids

A homing system targets therapeutic T cells to brain cancer

(2018) Heba Samaha et al.   NATURE

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

In vivo dynamics of AAV-mediated gene delivery to sensory neurons of the trigeminal ganglia

(2017) Chung H. Dang et al.   Scientific Reports

Adeno-associated virus (AAV) vectors in cancer gene therapy

(2016) Jorge L. Santiago-Ortiz et al.   JOURNAL OF CONTROLLED RELEASE

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

(2016) Weiping Zou et al.   Science Translational Medicine

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

T cell exclusion, immune privilege, and the tumor microenvironment

(2015) J. A. Joyce et al.   SCIENCE

Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors

(2015) Robert C. Münch et al.   Nature Communications

Engineering adeno-associated viruses for clinical gene therapy

(2014) Melissa A. Kotterman et al.   NATURE REVIEWS GENETICS

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

(2011) Amit C. Nathwani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

(2009) Albert M Maguire et al.   LANCET

A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells

(2009) Richard H Smith et al.   MOLECULAR THERAPY

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

(2008) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thymidine kinase 1 as a molecular target for boron neutron capture therapy of brain tumors

(2008) R. F. Barth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA