Smooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis

Statin mediated cholesterol depletion exerts coordinated effects on the alterations in rat vascular smooth muscle cell biomechanics and migration

(2020) Hanna J. Sanyour et al.   JOURNAL OF PHYSIOLOGY-LONDON

Promoters to Study Vascular Smooth Muscle

(2019) Raja Chakraborty et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

(2019) Robert C. Wirka et al.   NATURE MEDICINE

Vascular smooth muscle cells in atherosclerosis

(2019) Gemma L. Basatemur et al.   Nature Reviews Cardiology

Membrane-associated periodic skeleton is a signaling platform for RTK transactivation in neurons

(2019) Ruobo Zhou et al.   SCIENCE

SM22α (Smooth Muscle 22α) Prevents Aortic Aneurysm Formation by Inhibiting Smooth Muscle Cell Phenotypic Switching Through Suppressing Reactive Oxygen Species/NF-κB (Nuclear Factor-κB)

(2018) Lintao Zhong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease inAtp7B−/−(Wilson disease) mice

(2016) James P. Hamilton et al.   HEPATOLOGY

Cholesterol Loading Reprograms the MicroRNA-143/145–Myocardin Axis to Convert Aortic Smooth Muscle Cells to a Dysfunctional Macrophage-Like PhenotypeSignificance

(2015) Yuliya Vengrenyuk et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SM22α inhibits vascular inflammation via stabilization of IκBα in vascular smooth muscle cells

(2015) Ya-Nan Shu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

(2014) Sima Allahverdian et al.   CIRCULATION

Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

(2014) Susanne Feil et al.   CIRCULATION RESEARCH

Transcriptome profiling reveals that the SM22α-regulated molecular pathways contribute to vascular pathology

(2014) Rong Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics

(2013) Chin Yee Ho et al.   NATURE

Phosphorylation of Smooth Muscle 22α Facilitates Angiotensin II–Induced ROS Production Via Activation of the PKCδ-P47 phox Axis Through Release of PKCδ and Actin Dynamics and Is Associated With Hypertrophy and Hyperplasia of Vascular Smooth Muscle Cells In Vitro and In Vivo

(2012) Pin Lv et al.   CIRCULATION RESEARCH

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

(2012) Anna C. Calkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aortic Stiffness

(2011) João L. Cavalcante et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Blockade of the Ras–Extracellular Signal–Regulated Kinase 1/2 Pathway Is Involved in Smooth Muscle 22α–Mediated Suppression of Vascular Smooth Muscle Cell Proliferation and Neointima Hyperplasia

(2010) Li-Hua Dong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Liver X Receptor Signaling Pathways and Atherosclerosis

(2010) Anna C. Calkin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Disruption of SM22 Promotes Inflammation After Artery Injury via Nuclear Factor κB Activation

(2010) Jianbin Shen et al.   CIRCULATION RESEARCH

Liver X Receptor Signaling Is a Determinant of Stellate Cell Activation and Susceptibility to Fibrotic Liver Disease

(2010) Simon W. Beaven et al.   GASTROENTEROLOGY

Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF- B signalling

(2009) S. Wu et al.   CARDIOVASCULAR RESEARCH

ATP-Binding Cassette Transporter A1 Expression and Apolipoprotein A-I Binding Are Impaired in Intima-Type Arterial Smooth Muscle Cells

(2009) Hong Y. Choi et al.   CIRCULATION

Smooth muscle 22 alpha maintains the differentiated phenotype of vascular smooth muscle cells by inducing filamentous actin bundling

(2008) Mei Han et al.   LIFE SCIENCES

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE