Article
Physics, Fluids & Plasmas
Akiho Tani, Yutaro Tanii, Kyoka Ishiyama, Shusaku Harada, Hisao Satoh
Summary: Monte Carlo simulations were used to investigate the structural change of hard sphere-platelet mixtures under different particle sizes. The results showed that the size and density of the particles have different effects on the structural transitions of platelet and spherical particles.
Article
Mechanics
Haibing Peng
Summary: Despite the widespread use of Navier-Stokes equations in computational-fluid-dynamics (CFD), there are still unanswered questions due to the absence of considering the statistical nature of discrete air molecules. In this study, we propose a statistical mechanics-based approach called the volume-element method, which allows for the numerical evaluation of aerodynamic lift and drag. We obtained pressure and friction values as a function of the angle of attack for flat-plate airfoils, and this method can be directly applied to convex-shape airfoils and combined with Monte Carlo simulations for concave-shape airfoils. This approach not only has implications for aerodynamic applications, but also opens up possibilities for further applications in Boson or Fermi gases.
Article
Green & Sustainable Science & Technology
Thomas Hennequin, Mark A. J. Huijbregts, Rosalie van Zelm
Summary: Understanding the influence of consumer behavior on the life cycle of car tires, it was found that promoting the use of smaller cars and longer-lasting, fuel-efficient tires can effectively reduce environmental impacts.
JOURNAL OF INDUSTRIAL ECOLOGY
(2023)
Article
Environmental Sciences
Thien An Dao Nguyen, Linh Thi Nguyen, Alexis Enright, Luu Thanh Pham, Hoang Yen Thi Tran, Thai Thanh Tran, Van Ha Thi Nguyen, Dang Ngoc Tran
Summary: Cyanotoxins released by cyanobacteria pose health risks to people living near the Tri An Reservoir in Dong Nai Province, Vietnam, with microcystin (MC) concentrations exceeding the WHO's permitted level. Results from Monte Carlo simulation technique showed that the rate of MC exposure likely to cause cancer is approximately 1-5%, while oral exposure rate while bathing is less than 2.5%.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Physics, Multidisciplinary
K. L. Zhang, Z. Song
Summary: The study reveals that applying a nonlocal non-Hermitian perturbation to an Ising chain merges the topological Kramer-like degeneracy in the ferromagnetic phase, with distinct dynamic responses for different quantum phases. The phase diagram at zero temperature is completely preserved at finite temperatures.
PHYSICAL REVIEW LETTERS
(2021)
Article
Environmental Sciences
Lei Fu, Shaofang Song, Xinni Luo, Yangxu Luo, Chongshan Guo, Yufei Liu, Xiaoyan Luo, Lixi Zeng, Lei Tan
Summary: This study investigated the relationship between dietary exposure and human internal exposure to phthalates. The results showed that dietary intake was the predominant exposure route for phthalates, and children exhibited the highest concentration of phthalate metabolites (mPAEs). Using Monte Carlo simulation to estimate phthalate exposure's health risk, it was found that a significant portion of the volunteers had hazard quotient (HQ) levels higher than 1.
ENVIRONMENTAL POLLUTION
(2023)
Article
Biochemical Research Methods
Sanmitra Ghosh, Paul J. Birrell, Daniela De Angelis
Summary: In this paper, a computationally efficient method is proposed to quantify the uncertainty in transmission ability during an epidemic. This method does not make assumptions about the timing and magnitude of the impacts of external stimuli on transmission. The proposed approach is valuable for real-time monitoring of epidemics and has been demonstrated through examples of influenza, seasonality, and COVID-19 modeling.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Samara P. Souza, Monique F. Silva, Otavio J. Tavares, Lucas W. G. Souza, Daniela C. Silva, William S. Santos, Walmir Belinato, Ana P. Perini, Lucio P. Neves
Summary: In UAE procedures, the radiation doses received by professionals and patients need special attention. Results showed that using protective equipment can effectively reduce the radiation exposure risk for physicians and assistants.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2021)
Article
Food Science & Technology
Bozidar Udovicki, Nikola Tomic, Bojana Spirovic Trifunovic, Sasa Despotovic, Jelena Jovanovic, Liesbeth Jacxsens, Andreja Rajkovic
Summary: The study analyzed the exposure to aflatoxin B1 (AFB1) in commonly consumed foods in Serbia, finding that children had the highest exposure levels, raising concerns for their health. The Margin of Exposure (MOE) calculation and estimation of potential hepatocellular carcinoma (HCC) cases revealed low MOE values and a range of possible HCC cases per year based on population groups.
FOOD AND CHEMICAL TOXICOLOGY
(2021)
Article
Optics
Ruoyu Chen, Shanbao Tong, Peng Miao
Summary: This study proposes a deep-learning-based strategy for high spatiotemporal resolution three-dimensional (3D) reconstruction from a single transilluminated laser speckle contrast image, providing more structural and functional details without multifocus two-dimensional (2D) imaging or 3D optical imaging with point/line scanning. The method utilizes convolution of vessel masks with depth-dependent point spread functions (PSF) to generate a large training dataset, and employs UNet and ResNet for deblurring and depth estimation. The blood flow in the reconstructed 3D vessels is estimated by a depth-dependent contrast model. The proposed method achieves high-fidelity structural reconstruction with a depth-independent estimation of blood flow, and is suitable for real-time monitoring of thick tissue and the diagnosis of vascular diseases.
Article
Environmental Sciences
Yu-Fang Huang, Jui-Pin Chang, Hsin-Chang Chen, Xuan-Rui Liu
Summary: The study found various benzophenone derivatives in saltwater and freshwater fish samples from Taiwan. Research on eight age groups showed that although there were residues, the intake of benzophenone derivatives through fish consumption is not a health concern for Taiwanese people.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Studies
Miguel Jaller, Runhua (Ivan) Xiao, Sarah Dennis-Bauer, Daniel Rivera-Royero, Anmol Pahwa
Summary: This study investigates the potential impact of e-commerce on shopping behaviors, travel, and residential deliveries by the year 2050. It develops a comprehensive modeling framework to predict changes in shopping behavior and estimate parameters associated with shopping travel and last-mile delivery alternatives. The findings suggest that population growth and socio-demographic factors will have different effects on shopping behaviors across various areas, and shopping travel and delivery patterns are influenced by the spatial distribution of trips and transportation mode selection.
TRANSPORTATION RESEARCH PART D-TRANSPORT AND ENVIRONMENT
(2023)
Article
Microbiology
Ronald G. Hall, Shuhan Liu, William C. Putnam, Rajareddy Kallem, Tawanda Gumbo, Manjunath P. Pai
Summary: Echinocandins like anidulafungin are first-line therapies for candidemia and invasive candidiasis, but their dosing may be suboptimal in obese patients. This study aimed to evaluate the impact of body size on anidulafungin pharmacokinetics (PK) and found that a higher maintenance dose of anidulafungin is needed in larger adults to achieve the desired effect.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2023)
Article
Chemistry, Physical
Shiyan Wang, Anirudh Venkatesh, Doraiswami Ramkrishna, Vivek Narsimhan
Summary: A Brownian bridge is a continuous random walk guided by an effective drift to control the endpoint of a stochastic process. While widely applicable in chemical science, the main limitation is the difficulty in determining the effective drift and solving the complex Backward Fokker-Planck equation.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Engineering, Environmental
A. Marcelli, L. Fattorini, S. Franceschi
Summary: The study discusses using the inverse distance weighting interpolator and deriving map properties from a design perspective to avoid complex modeling tasks and proposes conditions for ensuring map consistency. Traditional estimator is commonly used for estimating domain totals, resulting in discrepancies with total estimates obtained from maps, hence suggesting harmonization of maps to achieve consistent results.
STOCHASTIC ENVIRONMENTAL RESEARCH AND RISK ASSESSMENT
(2022)
Article
Environmental Sciences
Cong Zhou, Xiyuan Xiao, Zhaohui Guo, Chi Peng, Peng Zeng, Ataa Fosua Bridget
Summary: Under 5 mg L-1Cd stress, H. spectabile exhibited normal growth and physiological response, with high shoot Cd accumulation, making it a suitable candidate for phytoextraction in low-level Cd polluted environments.
INTERNATIONAL JOURNAL OF PHYTOREMEDIATION
(2021)
Article
Environmental Sciences
Zhaohui Guo, Peng Zeng, Xiyuan Xiao, Chi Peng
Summary: Mulberry shows strong detoxification and self-protection abilities against Cd stress, with minimal impact on growth and photosynthetic pigment contents within a certain range of Cd content, while exhibiting positive correlation between antioxidant enzyme activities and Cd content in plants.
ENVIRONMENTAL POLLUTION
(2021)
Article
Engineering, Environmental
Lei Shi, Zhaohui Guo, Shuaixia Liu, Xiyuan Xiao, Chi Peng, Wenli Feng, Hongzhen Ran, Peng Zeng
Summary: The study investigated the reduction effects of combined soil amendments on Cd content and Cd/Zn ratio in rice grains in soils with different Cd contamination levels in three regions of Hunan province, China. The combined amendments, especially lime combined with organic fertilizer, proved to be effective in reducing Cd content in rice grains and Cd/Zn ratio, as well as decreasing soil available Cd and Zn concentration.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2022)
Article
Environmental Sciences
Zhichao Jiang, Zhaohui Guo, Chi Peng, Xu Liu, Ziruo Zhou, Xiyuan Xiao
Summary: The study assessed the contamination and health risks of heavy metals in soils around various types of non-ferrous smelteries in China, finding that some provinces had severe soil pollution exceeding standards, especially around copper smelteries. Strategies to control soil pollution around non-ferrous smelteries should primarily focus on Cd and Pb.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Zhichao Jiang, Zhaohui Guo, Chi Peng, Richmond Anaman, Hongzhen Ran, Xiyuan Xiao
Summary: Soil particle size has a significant impact on the adsorption of Cd in soils, with larger particles having lower adsorption capacity. Cd adsorption is related to the exchange with Fe/Al in the soil, and -OH/C=O sites are the main adsorption sites. Miscellaneous fill in zinc smelting sites may pose a secondary pollution risk due to its low adsorption ability for Cd.
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2022)
Article
Environmental Sciences
Peng Zeng, Zhaohui Guo, Xiyuan Xiao, Chi Peng, Bohan Liao, Hang Zhou, Jiaofeng Gu
Summary: This study investigated the potential of tree-herb intercropping for the ecological remediation of PTM-contaminated soil. The results showed that the intercropping system improved the growth of Morus alba L. and increased the uptake of PTMs. The intercropping also enhanced the biological quality of the contaminated soil and increased the relative abundance of microorganisms.
Review
Environmental Sciences
Y. He, C. Peng, Y. Zhang, Z. Guo, X. Xiao, L. Kong
Summary: By collecting heavy metal data from soil and dust samples in 34 cities in China, this study found that the concentrations of Cd, Pb, Cu, and Zn in urban street dust were generally higher than those in urban soil. The main reasons for the high metal concentrations in some cities were the development of metal processing and smelting industries, manufacturing, and the relocation of heavily polluting enterprises. The heavy metal concentrations in urban soil were not correlated with those in urban dust, indicating different long-term and short-term sources of pollution. In most cities, the non-carcinogenic risk of heavy metals in urban soil and dust for children was at a safe level, with lead being the major contributor to total health risk.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2023)
Article
Environmental Sciences
Chi Peng, Kai Zhang, Meie Wang, Xinxing Wan, Weiping Chen
Summary: Heavy metal concentrations in urban soils are likely to increase due to urbanization and emissions. The accumulation rates of heavy metals in urban soils varied among cities and were influenced by soil parent material and anthropogenic sources. Cd and Cu accumulation rates were similar across the three cities, while Zn and Pb accumulation rates were higher in Shanghai. Although urbanization led to elevated concentrations of Cd, Cu, Zn, and Pb in residential soils, the overall health risks for residents were negligible.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2022)
Article
Environmental Sciences
Richmond Anaman, Chi Peng, Zhichao Jiang, Xu Liu, Ziruo Zhou, Zhaohui Guo, Xiyuan Xiao
Summary: This study successfully identified the sources, transport routes, and apportionment of heavy metals in soil around a smelting site using principal component analysis, positive matrix factorization, and geographic information system mapping. The results showed that the soil was contaminated with various heavy metals, with smelter emissions and soil parent materials being the primary sources. GIS visualization revealed that surface runoff and atmospheric deposition were the main transport routes for the heavy metals, with different land uses receiving varying degrees of contamination.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Multidisciplinary
Zhi Xu, Yulian Hu, Zhaohui Guo, Xiyuan Xiao, Chi Peng, Peng Zeng
Summary: This study investigated the pyrolysis of rice straw at different temperatures for producing biochar to treat heavy metal(loid)-contaminated RS. It was found that increasing temperature volatilized the heavy metal(loid)s, with Cd being the most volatile metal. Furthermore, biochars produced at higher temperatures showed higher Pb adsorption capacity and reduced vertical Pb migration.
JOURNAL OF SAUDI CHEMICAL SOCIETY
(2022)
Article
Environmental Sciences
Xiaohui Wang, Cong Zhou, Xiyuan Xiao, Zhaohui Guo, Chi Peng, Xiaoyan Wang
Summary: This study found that intercropping with hyperaccumulators/accumulators can promote plant growth, enhance soil bacterial community diversity, and improve the phytoextraction of heavy metal(loid)s.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Ziruo Zhou, Chi Peng, Xu Liu, Zhichao Jiang, Zhaohui Guo, Xiyuan Xiao
Summary: Pb-Zn smelting is a major source of heavy metal(loid) contamination in soils. The study found severe contamination of arsenic, cadmium, lead, and zinc within a 2 km distance to the smelteries, posing potential ecological and health risks.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Eric Tindanzor, Zhaohui Guo, Tianshuang Li, Rui Xu, Xiyuan Xiao, Chi Peng
Summary: This study compared the removal performance of oxalic acid, citric acid, and a copolymer of maleic and acrylic acid on heavy metals in polluted soil. The results showed that the sequential use of citric acid and oxalic acid was the best alternative to EDTA, with higher metal removal efficiency and successful support for crop germination.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Chi Peng, Yalei He, Kai Zhang, Yan Zhang, Xinxing Wan, Meie Wang, Weiping Chen
Summary: Predicting temporal changes in PAH concentrations in urban soils is crucial for managing health risks. This study found that PAH concentrations in residential areas of metropolitan cities increase with building age, indicating an increasing health risk over time.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Environmental Sciences
Zhaohui Guo, Yunxia Zhang, Rui Xu, Huimin Xie, Xiyuan Xiao, Chi Peng
Summary: This study developed a machine learning model to investigate the vertical distribution and prediction of metal(loid)s in a typical abandoned Pb/Zn smelter site. The results demonstrated that the model was effective in identifying key factors influencing contamination distribution and predicting metal(loid)s contents in subsurface soil. Arsenic (As), cadmium (Cd), lead (Pb), and zinc (Zn) were found to be the primary pollutants with migration depths of 4-6 m.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)