Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis

The Rise of Molecular Glues

(2021) Stuart L. Schreiber   CELL

Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes

(2021) Tobias E. Spikes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch

(2020) Meghna Sobti et al.   Nature Communications

A systematic assessment of mycobacterial F 1 ‐ATPase subunit ε’s role in latent ATPase hydrolysis

(2020) Chui‐Fann Wong et al.   FEBS Journal

Structure of the dimeric ATP synthase from bovine mitochondria

(2020) Tobias E. Spikes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of Vo complex

(2020) Soung-Hun Roh et al.   Science Advances

Bedaquiline inhibits the yeast and human mitochondrial ATP synthases

(2020) Min Luo et al.   Communications Biology

Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline

(2020) Hui Guo et al.   NATURE

The structure of the catalytic domain of the ATP synthase fromMycobacterium smegmatisis a target for developing antitubercular drugs

(2019) Alice Tianbu Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a bacterial ATP synthase

(2019) Hui Guo et al.   eLife

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis

(2019) Wuan-Geok Saw et al.   Scientific Reports

The regulatory subunit ε in Escherichia coli F O F 1 -ATP synthase

(2018) Hendrik Sielaff et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

New tools for the analysis and validation of cryo-EM maps and atomic models

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane

(2017) Laura Chiaradia et al.   Scientific Reports

Deletion of a unique loop in the mycobacterial F-ATP synthase γ subunit sheds light on its inhibitory role in ATP hydrolysis-driven H+pumping

(2016) Adam Hotra et al.   FEBS Journal

Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states

(2016) Meghna Sobti et al.   eLife

Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase

(2015) Matteo Allegretti et al.   NATURE

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

Structure of ATP synthase fromParacoccus denitrificansdetermined by X-ray crystallography at 4.0 Å resolution

(2015) Edgar Morales-Rios et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the mycobacterial ATP synthase Fo rotor ring in complex with the anti-TB drug bedaquiline

(2015) L. Preiss et al.   Science Advances

ATP synthase in mycobacteria: Special features and implications for a function as drug target

(2014) Ping Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The ATP synthase: the understood, the uncertain and the unknown

(2013) John E. Walker   BIOCHEMICAL SOCIETY TRANSACTIONS

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria

(2010) I. N. Watt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Torque generation and elastic power transmission in the rotary FOF1-ATPase

(2009) Wolfgang Junge et al.   NATURE

High-resolution structure of the rotor ring of a proton-dependent ATP synthase

(2009) Denys Pogoryelov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY