Passive coupling of membrane tension and cell volume during active response of cells to osmosis

LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions

(2021) Selma A. Serra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A single-cell identification and capture chip for automatically and rapidly determining hydraulic permeability of cells

(2020) Yeye Xu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance

(2020) Margot Riggi et al.   JOURNAL OF CELL SCIENCE

The relative densities of cytoplasm and nuclear compartments are robust against strong perturbation

(2020) Kyoohyun Kim et al.   BIOPHYSICAL JOURNAL

Pay attention to membrane tension: Mechanobiology of the cell surface

(2020) Ewa Sitarska et al.   CURRENT OPINION IN CELL BIOLOGY

SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism

(2020) Ashutosh Kumar et al.   eLife

Characterization of Single-Cell Osmotic Swelling Dynamics for New Physical Biomarkers

(2020) Apresio K. Fajrial et al.   ANALYTICAL CHEMISTRY

Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate

(2020) Henry De Belly et al.   Cell Stem Cell

mTOR: A Cellular Regulator Interface in Health and Disease

(2019) Fahd Boutouja et al.   Cells

TORC2 controls endocytosis through plasma membrane tension

(2019) Margot Riggi et al.   JOURNAL OF CELL BIOLOGY

The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1

(2019) Wael L. Demian et al.   Cell Reports

Dynamic Regulation of Caveolin-1 Phosphorylation and Caveolae Formation by Mammalian Target of Rapamycin Complex 2 in Bladder Cancer Cells

(2019) Andrew M. Hau et al.   AMERICAN JOURNAL OF PATHOLOGY

The plasma membrane as a mechanochemical transducer

(2019) Anabel-Lise Le Roux et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A FRET sensor of C-terminal movement reveals VRAC activation by plasma membrane DAG signaling rather than ionic strength

(2019) Benjamin König et al.   eLife

Akt-ing Up Just About Everywhere: Compartment-Specific Akt Activation and Function in Receptor Tyrosine Kinase Signaling

(2019) Michael G. Sugiyama et al.   Frontiers in Cell and Developmental Biology

Cellular Blebs and Membrane Invaginations Are Coupled through Membrane Tension Buffering

(2019) Ido Lavi et al.   BIOPHYSICAL JOURNAL

Hypotonic Challenge of Endothelial Cells Increases Membrane Stiffness with No Effect on Tether Force

(2018) Manuela Aseye Ayele Ayee et al.   BIOPHYSICAL JOURNAL

Controlling Cellular Volume via Mechanical and Physical Properties of Substrate

(2018) Kenan Xie et al.   BIOPHYSICAL JOURNAL

mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding

(2018) M. Delarue et al.   CELL

Mechanical Mapping of Spinal Cord Growth and Repair in Living Zebrafish Larvae by Brillouin Imaging

(2018) Raimund Schlüßler et al.   BIOPHYSICAL JOURNAL

Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2

(2018) Margot Riggi et al.   NATURE CELL BIOLOGY

A fluorescent membrane tension probe

(2018) Adai Colom et al.   Nature Chemistry

Cell volume change through water efflux impacts cell stiffness and stem cell fate

(2017) Ming Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength

(2016) Ruhma Syeda et al.   CELL

VRACs and other ion channels and transporters in the regulation of cell volume and beyond

(2016) Thomas J. Jentsch   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mapping intracellular mechanics on micropatterned substrates

(2016) Kalpana Mandal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration

(2016) Alba Diz-Muñoz et al.   PLOS BIOLOGY

Caveolae - mechanosensitive membrane invaginations linked to actin filaments

(2015) A. Echarri et al.   JOURNAL OF CELL SCIENCE

Fluorescent Flippers for Mechanosensitive Membrane Probes

(2015) Marta Dal Molin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping

(2015) Oliver Otto et al.   NATURE METHODS

A balance between membrane elasticity and polymerization energy sets the shape of spherical clathrin coats

(2015) Mohammed Saleem et al.   Nature Communications

TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1

(2015) Monika Plescher et al.   Scientific Reports

mTOR ensures increased release and reduced uptake of the organic osmolyte taurine under hypoosmotic conditions in mouse fibroblasts

(2014) Ian Henry Lambert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The ion channels to cytoskeleton connection as potential mechanism of mechanosensitivity

(2013) Boris Martinac   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane tension homeostasis of epithelial cells through surface area regulation in response to osmotic stress

(2012) Anna Pietuch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulatory volume decrease in COS-7 cells at 22°C and its influence on the Boyle van’t Hoff relation and the determination of the osmotically inactive volume

(2012) Diana Peckys et al.   CRYOBIOLOGY

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis

(2012) Doris Berchtold et al.   NATURE CELL BIOLOGY

Use the force: membrane tension as an organizer of cell shape and motility

(2012) Alba Diz-Muñoz et al.   TRENDS IN CELL BIOLOGY

On the Distribution of Protein Refractive Index Increments

(2011) Huaying Zhao et al.   BIOPHYSICAL JOURNAL

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

On proper linearization, construction and analysis of the Boyle–van’t Hoff plots and correct calculation of the osmotically inactive volume

(2011) Igor I. Katkov   CRYOBIOLOGY

Actin dynamics counteract membrane tension during clathrin-mediated endocytosis

(2011) Steeve Boulant et al.   NATURE CELL BIOLOGY

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

(2010) Qingsong Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding

(2010) Martin P. Stewart et al.   NATURE

The F-BAR Domain of srGAP2 Induces Membrane Protrusions Required for Neuronal Migration and Morphogenesis

(2009) Sabrice Guerrier et al.   CELL

The Sodium-Hydrogen Exchanger NHE1 Is an Akt Substrate Necessary for Actin Filament Reorganization by Growth Factors

(2009) Marcel E. Meima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

Universal behavior of the osmotically compressed cell and its analogy to the colloidal glass transition

(2009) E. H. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonlinear Osmotic Properties of the Cell Nucleus

(2008) John D. Finan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Membrane mechanics as a probe of ion-channel gating mechanisms

(2008) Daniel Reeves et al.   PHYSICAL REVIEW E