Thiol-Ene “Click Reactions” as a Promising Approach to Polymer Materials

Boronate affinity sorbents based on thiol-functionalized polysiloxane-polymethacrylate composite materials in syringe format for selective extraction of glycopeptides

(2021) Óscar Mompó-Roselló et al.   MICROCHEMICAL JOURNAL

Thiol-ene Click Chemistry Construct Superhydrophobic Cotton Fabric for High-efficiency Water-in-oil Emulsion Separation

(2020) Guihua Meng et al.   FIBERS AND POLYMERS

Gellan gum and its methacrylated derivatives as in situ gelling mucoadhesive formulations of pilocarpine: In vitro and in vivo studies

(2020) Laura E. Agibayeva et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

3D Extracellular Matrix Mimics: Fundamental Concepts and Role of Materials Chemistry to Influence Stem Cell Fate

(2020) Julien Nicolas et al.   BIOMACROMOLECULES

Cytocompatible and non-fouling zwitterionic hyaluronic acid-based hydrogels using thiol-ene “click” chemistry for cell encapsulation

(2020) Yabin Zhang et al.   CARBOHYDRATE POLYMERS

Solvent Effects on Thiol–Ene Kinetics and Reactivity of Carbon and Sulfur Radicals

(2020) Ipek Munar et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Effects of 1°, 2°, and 3° Thiols on Thiol–Ene Reactions: Polymerization Kinetics and Mechanical Behavior

(2020) Katelyn F. Long et al.   MACROMOLECULES

Surface PEGylation of Polyacrylonitrile Membrane via Thiol-ene Click Chemistry for Efficient Separation of Oil-in-Water Emulsions

(2020) Xiang Shen et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Holographic Photopolymer Material with High Dynamic Range (Δn) via Thiol–Ene Click Chemistry

(2020) Yunfeng Hu et al.   ACS Applied Materials & Interfaces

Multithiol functionalized graphene bio-sponge via photoinitiated thiol-ene click chemistry for efficient heavy metal ions adsorption

(2020) Pei Lay Yap et al.   CHEMICAL ENGINEERING JOURNAL

One-Step Preparation of Superhydrophobic Cotton Fabric Based on Thiol-Ene Click Chemistry

(2020) Xinpeng Chen et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

A novel adsorbent based on aptamer prepared via “thiol-ene” click for specific recognition of phthalic acid esters

(2020) Qinghua Chu et al.   ANALYTICA CHIMICA ACTA

Thiol-ene click chemistry synthesis of a novel magnetic mesoporous silica/chitosan composite for selective Hg(II) capture and high catalytic activity of spent Hg(II) adsorbent

(2020) Haifeng He et al.   CHEMICAL ENGINEERING JOURNAL

Preparation and properties of high refractive index polythioetherimide film based on thiol-ene click chemistry

(2020) Jiandong Zuo et al.   PROGRESS IN ORGANIC COATINGS

Acrylated Eudragit® E PO as a novel polymeric excipient with enhanced mucoadhesive properties for application in nasal drug delivery

(2019) Natalia N. Porfiryeva et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Kinetics of Direct Photoinduced Addition of Carbosilane Thiols with Bulky Groups to Polyallylcarbosilane

(2019) E. A. Svidchenko et al.   POLYMER SCIENCE SERIES B

Facile construction of imidazole functionalized polysiloxanes by thiol-ene “Click” reaction for the consecutive detection of Fe3+ and amino acids

(2019) Yujing Zuo et al.   SENSORS AND ACTUATORS B-CHEMICAL

Click reactions: Recent trends in preparation of new sorbents and stationary phases for extraction and chromatographic applications

(2019) Sima Najafi Ghamat et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Use of thiol functionalities for the preparation of porous monolithic structures and modulation of their surface chemistry: A review

(2019) Luiz F. Ribeiro et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Maleimide-functionalised PLGA-PEG nanoparticles as mucoadhesive carriers for intravesical drug delivery

(2019) Daulet B. Kaldybekov et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Green synthesis of monolithic enzyme microreactor based on thiol-ene click reaction for enzymatic hydrolysis of protein

(2019) Xue Zhao et al.   JOURNAL OF CHROMATOGRAPHY A

Robust immobilized enzyme reactor based on trimethylolpropane trimethacrylate organic monolithic matrix through “thiol-ene” click reaction

(2019) Pei-Ru Fan et al.   EUROPEAN POLYMER JOURNAL

Modification of Polyurethane Sponge Based on the Thiol–Ene Click Reaction and Its Application for Oil/Water Separation

(2019) Liping Liang et al.   Polymers

Glucose Sensing with Phenylboronic Acid Functionalized Hydrogel-Based Optical Diffusers

(2018) Mohamed Elsherif et al.   ACS Nano

Ionic liquid syntheses via click chemistry: expeditious routes toward versatile functional materials

(2018) Arsalan Mirjafari   CHEMICAL COMMUNICATIONS

An unconventional chromophore in water-soluble polysiloxanes synthesized via thiol-ene reaction for metal ion detection

(2018) Jinfeng Cao et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Thiol-ene click derived structurally well-defined per(3,5-dimethyl)phenylcarbamoylated cationic cyclodextrin separation material for achiral and chiral chromatography

(2018) Xiaoying Tang et al.   JOURNAL OF SEPARATION SCIENCE

Controlling the Size of Thiolated Organosilica Nanoparticles

(2018) Jamila H. Al Mahrooqi et al.   LANGMUIR

Preparation of new biobased coatings from a triglycidyl eugenol derivative through thiol-epoxy click reaction

(2018) Dailyn Guzmán et al.   PROGRESS IN ORGANIC COATINGS

6-Maleimidohexanoic acid-grafted chitosan: A new generation mucoadhesive polymer

(2018) Nitjawan Sahatsapan et al.   CARBOHYDRATE POLYMERS

Methacrylated chitosan as a polymer with enhanced mucoadhesive properties for transmucosal drug delivery

(2018) Oluwadamilola M. Kolawole et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Zwitterionic Cross-Linked Biodegradable Nanocapsules for Cancer Imaging

(2018) Haotian Sun et al.   LANGMUIR

Bioinspired glycosaminoglycan hydrogels via click chemistry for 3D dynamic cell encapsulation

(2018) Liangju Kuang et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Thiol−Ene Reaction: Synthetic Aspects and Mechanistic Studies of an Anti-Markovnikov-Selective Hydrothiolation of Olefins

(2018) Arun K. Sinha et al.   Asian Journal of Organic Chemistry

A facile and efficient method to fabricate high-resolution immobilized cellulose-based chiral stationary phases via thiol-ene click chemistry

(2018) Chunchun Yin et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Click chemistry as a versatile reaction for construction and modification of metal-organic frameworks

(2018) Pei-Zhou Li et al.   COORDINATION CHEMISTRY REVIEWS

Thiol-ene polymerisation: A promising technique to obtain novel biomaterials

(2017) Thiago O. Machado et al.   EUROPEAN POLYMER JOURNAL

UV-mediated thiol-ene click reactions for the synthesis of drug-loadable and degradable gels based on copoly(2-oxazoline)s

(2017) Klaus P. Luef et al.   EUROPEAN POLYMER JOURNAL

Functionalization of hybrid monolithic columns via thiol-ene click reaction for proteomics analysis

(2017) Zhongshan Liu et al.   JOURNAL OF CHROMATOGRAPHY A

pH-sensitive nanogels with ortho ester linkages prepared via thiol-ene click chemistry for efficient intracellular drug release

(2017) Jun Wang et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Efficient Polymer-Polymer Conjugation via Thiol-ene Click Reaction

(2017) Benjamin D. Fairbanks et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Fabrication of superhydrophobic melamine sponges by thiol-ene click chemistry for oil removal

(2017) Kun Hou et al.   MATERIALS LETTERS

Modular photo-induced RAFT polymerised hydrogels via thiol–ene click chemistry for 3D cell culturing

(2017) Vincent T. G. Tan et al.   Polymer Chemistry

Synthesis of thioether-containing carbosilane dendrimers with sterically shielded sulfur atoms

(2017) А. N. Tarasenkov et al.   RUSSIAN CHEMICAL BULLETIN

Thiol–ene click reaction on cellulose sponge and its application for oil/water separation

(2017) Zhenzhen Wu et al.   RSC Advances

Click polymerization for preparation of monolithic columns for liquid chromatography

(2016) Zhongshan Liu et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Side chain variations radically alter the diffusion of poly(2-alkyl-2-oxazoline) functionalised nanoparticles through a mucosal barrier

(2016) Edward D. H. Mansfield et al.   Biomaterials Science

Maleimide-bearing nanogels as novel mucoadhesive materials for drug delivery

(2016) Prasopchai Tonglairoum et al.   Journal of Materials Chemistry B

Micro- and nanogels with labile crosslinks – from synthesis to biomedical applications

(2015) Xuejiao Zhang et al.   CHEMICAL SOCIETY REVIEWS

Ester-free thiol–ene dental restoratives—Part A: Resin development

(2015) Maciej Podgórski et al.   DENTAL MATERIALS

The Diels–Alder reaction: A powerful tool for the design of drug delivery systems and biomaterials

(2015) Manuel Gregoritza et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Redox- and glucose-responsive hydrogels from poly(vinyl alcohol) and 4-mercaptophenylboronic acid

(2015) Zhansaya A. Nurpeissova et al.   EUROPEAN POLYMER JOURNAL

In situ fabrication of paclitaxel-loaded core-crosslinked micelles via thiol-ene “click” chemistry for reduction-responsive drug release

(2015) Ying Huang et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

POZylation: a new approach to enhance nanoparticle diffusion through mucosal barriers

(2015) Edward D. H. Mansfield et al.   Nanoscale

Thiol-ene hydrogels as desmoplasia-mimetic matrices for modeling pancreatic cancer cell growth, invasion, and drug resistance

(2014) Chang Seok Ki et al.   BIOMATERIALS

Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering

(2014) Yanjiao Jiang et al.   BIOMATERIALS

“Click” reactions: a versatile toolbox for the synthesis of peptide-conjugates

(2014) Wen Tang et al.   CHEMICAL SOCIETY REVIEWS

Boronic acids for sensing and other applications - a mini-review of papers published in 2013

(2014) Karel Lacina et al.   Chemistry Central Journal

PEG-Based Microgels Formed by Visible-Light-Mediated Thiol-Ene Photo-Click Reactions

(2014) Andrew K. Fraser et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Cross-linked degradable poly( β -thioester) networks via amine-catalyzed thiol-ene click polymerization

(2014) Joke Vandenbergh et al.   POLYMER

Design of thiol–ene photoclick hydrogels using facile techniques for cell culture applications

(2014) Lisa A. Sawicki et al.   Biomaterials Science

Facile one-pot synthesis of glucose-sensitive nanogel via thiol-ene click chemistry for self-regulated drug delivery

(2013) Li Zhao et al.   Acta Biomaterialia

Efficient and accelerated growth of multifunctional dendrimers using orthogonal thiol–ene and SN2 reactions

(2013) Naresh Kottari et al.   CHEMICAL COMMUNICATIONS

The Thiol-Michael Addition Click Reaction: A Powerful and Widely Used Tool in Materials Chemistry

(2013) Devatha P. Nair et al.   CHEMISTRY OF MATERIALS

Oxime Ligation: A Chemoselective Click-Type Reaction for Accessing Multifunctional Biomolecular Constructs

(2013) Sébastien Ulrich et al.   CHEMISTRY-A EUROPEAN JOURNAL

Thiol–ene click chemistry derived cationic cyclodextrin chiral stationary phase and its enhanced separation performance in liquid chromatography

(2013) Xiaobin Yao et al.   JOURNAL OF CHROMATOGRAPHY A

Surface functionalization of cross-linked polystyrene microspheres via thiol–ene “click” reaction and assembly in honeycomb films for lectin recognition

(2013) Xuan Yang et al.   JOURNAL OF MATERIALS RESEARCH

Kinetic Modeling of Radical Thiol–Ene Chemistry for Macromolecular Design: Importance of Side Reactions and Diffusional Limitations

(2013) Pieter Derboven et al.   MACROMOLECULES

Nucleophilic thiol-Michael chemistry and hyperbranched (co)polymers: synthesis and ring-opening metathesis (co)polymerization of novel difunctional exo-7-oxanorbornenes with in situ inimer formation

(2013) Meina Liu et al.   Polymer Chemistry

Direct synthesis of hollow polymeric nanocapsules of variable shell thickness and rigidity

(2013) Ramjee Balasubramanian et al.   RSC Advances

Synthesis of thiolated and acrylated nanoparticles using thiol-ene click chemistry: towards novel mucoadhesive materials for drug delivery

(2013) Anna Štorha et al.   RSC Advances

Thiol–Ene Photopolymerizations Provide a Facile Method To Encapsulate Proteins and Maintain Their Bioactivity

(2012) Joshua D. McCall et al.   BIOMACROMOLECULES

Cross-Linking and Degradation of Step-Growth Hydrogels Formed by Thiol–Ene Photoclick Chemistry

(2012) Han Shih et al.   BIOMACROMOLECULES

Student award for outstanding research winner in the Ph.D. category for the 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012

(2012) Mark W. Tibbitt et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Cell-mediated delivery of glucocorticoids from thiol-ene hydrogels

(2012) Chun Yang et al.   JOURNAL OF CONTROLLED RELEASE

Cyclic polymers: Methods and strategies

(2012) Zhongfan Jia et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Synthesis of (Bio)-Degradable Poly(β-thioester)s via Amine Catalyzed Thiol−Ene Click Polymerization

(2012) Joke Vandenbergh et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Preparation and properties of cyclic acetal based biodegradable gel by thiol-ene photopolymerization

(2012) Kemin Wang et al.   Materials Science & Engineering C-Materials for Biological Applications

Biological surface modification by ‘thiol-ene’ addition of polymers synthesised by catalytic chain transfer polymerisation (CCTP)

(2012) Stacy Slavin et al.   Polymer Chemistry

Nitrogen-Centered Nucleophile Catalyzed Thiol-Vinylsulfone Addition, Another Thiol-ene “Click” Reaction

(2012) Weixian Xi et al.   ACS Macro Letters

Clicking Well-Defined Biodegradable Nanoparticles and Nanocapsules by UV-Induced Thiol-Ene Cross-Linking in Transparent Miniemulsions

(2011) Jiong Zou et al.   ADVANCED MATERIALS

Thiol–yne and Thiol–ene “Click” Chemistry as a Tool for a Variety of Platinum Drug Delivery Carriers, from Statistical Copolymers to Crosslinked Micelles

(2011) Vien T. Huynh et al.   BIOMACROMOLECULES

PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids

(2011) Chien-Chi Lin et al.   BIOMATERIALS

Recent applications of thiol–ene coupling as a click process for glycoconjugation

(2011) Alessandro Dondoni et al.   CHEMICAL SOCIETY REVIEWS

Vinyl functionalized silica hybrid monolith-based trypsin microreactor for on line digestion and separation via thiol-ene “click” strategy

(2011) Yingzhuang Chen et al.   JOURNAL OF CHROMATOGRAPHY A

Thiolated Mucoadhesive and PEGylated Nonmucoadhesive Organosilica Nanoparticles from 3-Mercaptopropyltrimethoxysilane

(2011) Galiya S. Irmukhametova et al.   LANGMUIR

Hydrogen-Bonding-Driven Self-Assembly of PEGylated Organosilica Nanoparticles with Poly(acrylic acid) in Aqueous Solutions and in Layer-by-Layer Deposition at Solid Surfaces

(2011) Galiya S. Irmukhametova et al.   LANGMUIR

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate

(2010) Christopher D. Pritchard et al.   BIOMATERIALS

Novel mucoadhesive system based on sulfhydryl-acrylate interactions

(2010) Maya Davidovich-Pinhas et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Limitations of radical thiol-ene reactions for polymer-polymer conjugation

(2010) Sandy P. S. Koo et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Accelerated Growth of Dendrimers via Thiol−Ene and Esterification Reactions

(2010) Maria I. Montañez et al.   MACROMOLECULES

Synthesis of Stereoregular Cyclic Poly(lactide)s via “Thiol−Ene” Click Chemistry

(2010) Matthew J. Stanford et al.   MACROMOLECULES

Conjugation of RAFT-generated polymers to proteins by two consecutive thiol–ene reactions

(2010) Ming Li et al.   Polymer Chemistry

Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein delivery

(2009) Alex A. Aimetti et al.   BIOMATERIALS

Synthesis of thiol-linked neoglycopolymers and thermo-responsive glycomicelles as potential drug carrier

(2009) Gaojian Chen et al.   CHEMICAL COMMUNICATIONS

Phosphine-mediated one-pot thiol–ene “click” approach to polymer–protein conjugates

(2009) Mathew W. Jones et al.   CHEMICAL COMMUNICATIONS

Stabilization and Functionalization of Polymer Multilayers and Capsules via Thiol−Ene Click Chemistry

(2009) Luke A. Connal et al.   CHEMISTRY OF MATERIALS

A New Ligation Strategy for Peptide and Protein Glycosylation: Photoinduced Thiol-Ene Coupling

(2009) Alessandro Dondoni et al.   CHEMISTRY-A EUROPEAN JOURNAL

Orthogonal “Relay” Reactions for Designing Functionalized Soft Nanoparticles

(2009) Hamilton Kakwere et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequential Phosphine-Catalyzed, Nucleophilic Thiol−Ene/Radical-Mediated Thiol−Yne Reactions and the Facile Orthogonal Synthesis of Polyfunctional Materials

(2009) Justin W. Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trapping of Thiol-Terminated Acrylate Polymers with Divinyl Sulfone To Generate Well-Defined Semitelechelic Michael Acceptor Polymers

(2009) Gregory N. Grover et al.   MACROMOLECULES

The nucleophilic, phosphine-catalyzed thiol–ene click reaction and convergent star synthesis with RAFT-prepared homopolymers

(2009) Justin W. Chan et al.   POLYMER

The effect of thiol and ene structures on thiol–ene networks: Photopolymerization, physical, mechanical and optical properties

(2009) Qin Li et al.   POLYMER

Hybrid organic–inorganic coatings based on thiol-ene systems

(2009) M. Sangermano et al.   REACTIVE & FUNCTIONAL POLYMERS

Highly Versatile and Robust Materials for Soft Imprint Lithography Based on Thiol-ene Click Chemistry

(2008) Luis M. Campos et al.   ADVANCED MATERIALS

Photochemical Surface Patterning by the Thiol-Ene Reaction

(2008) Pascal Jonkheijm et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Convergent synthesis of 3-arm star polymers from RAFT-prepared poly(N,N-diethylacrylamide) via a thiol–ene click reaction

(2008) Justin W. Chan et al.   CHEMICAL COMMUNICATIONS

Robust, Efficient, and Orthogonal Synthesis of Dendrimers via Thiol-ene “Click” Chemistry

(2008) Kato L. Killops et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The development of microgels/nanogels for drug delivery applications

(2008) Jung Kwon Oh et al.   PROGRESS IN POLYMER SCIENCE

Oxidation-responsiveness of nanomaterials for targeting inflammatory reactions

(2008) Vitaliy V. Khutoryanskiy et al.   PURE AND APPLIED CHEMISTRY