Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice

A Comparison of Isolation Stress and Unpredictable Chronic Mild Stress for the Establishment of Mouse Models of Depressive Disorder

(2021) Jin-Seok Lee et al.   Frontiers in Behavioral Neuroscience

Repeated social defeat stress induces neutrophil mobilization in mice: maintenance after cessation of stress and strain‐dependent difference in response

(2020) Yuka Ishikawa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Importin α3 regulates chronic pain pathways in peripheral sensory neurons

(2020) Letizia Marvaldi et al.   SCIENCE

Object Recognition Memory: Distinct Yet Complementary Roles of the Mouse CA1 and Perirhinal Cortex

(2020) David A. Cinalli Jr. et al.   Frontiers in Molecular Neuroscience

Targeting TNFR2 as a Novel Therapeutic Strategy for Alzheimer’s Disease

(2019) Natalia Ortí-Casañ et al.   Frontiers in Neuroscience

Neuro-Immune Mechanisms Regulating Social Behavior: Dopamine as Mediator?

(2019) Ashley M. Kopec et al.   TRENDS IN NEUROSCIENCES

Adolescent psychosocial stress enhances sensitization to cocaine exposure in genetically vulnerable mice

(2019) Takatoshi Hikida et al.   NEUROSCIENCE RESEARCH

Prolactin — a pleiotropic factor in health and disease

(2019) Valérie Bernard et al.   Nature Reviews Endocrinology

Cytokine Research in Depression: Principles, Challenges, and Open Questions

(2019) Hubertus Himmerich et al.   Frontiers in Psychiatry

Neurobiology and consequences of social isolation stress in animal model—A comprehensive review

(2018) Faiza Mumtaz et al.   BIOMEDICINE & PHARMACOTHERAPY

Blood biomarkers of Hikikomori, a severe social withdrawal syndrome

(2018) Kohei Hayakawa et al.   Scientific Reports

Revisiting the Role of Eotaxin-1/CCL11 in Psychiatric Disorders

(2018) Antonio L. Teixeira et al.   Frontiers in Psychiatry

Importin α5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1

(2018) Nicolas Panayotis et al.   Cell Reports

Too Depressed to Swim or Too Afraid to Stop? A Reinterpretation of the Forced Swim Test as a Measure of Anxiety-Like Behavior

(2017) Jeffrey Anyan et al.   NEUROPSYCHOPHARMACOLOGY

Importin α: a key molecule in nuclear transport and non-transport functions

(2016) Yoichi Miyamoto et al.   JOURNAL OF BIOCHEMISTRY

CXCL5 signaling is a shared pathway of neuroinflammation and blood–brain barrier injury contributing to white matter injury in the immature brain

(2016) Lin-Yu Wang et al.   Journal of Neuroinflammation

Gene expression elucidates functional impact of polygenic risk for schizophrenia

(2016) Menachem Fromer et al.   NATURE NEUROSCIENCE

The consolidation of inhibitory avoidance memory in mice depends on the intensity of the aversive stimulus: The involvement of the amygdala, dorsal hippocampus and medial prefrontal cortex

(2016) L. Canto-de-Souza et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling

(2016) Kohji Yamada et al.   Scientific Reports

Reduced Prepulse Inhibition as a Biomarker of Schizophrenia

(2016) Auxiliadora Mena et al.   Frontiers in Behavioral Neuroscience

The Functional Networks of Prepulse Inhibition: Neuronal Connectivity Analysis Based on FDG-PET in Awake and Unrestrained Rats

(2016) Cathrin Rohleder et al.   Frontiers in Behavioral Neuroscience

Actions of Prolactin in the Brain: From Physiological Adaptations to Stress and Neurogenesis to Psychopathology

(2016) Luz Torner   Frontiers in Endocrinology

The Neuroendocrinology of Social Isolation

(2015) John T. Cacioppo et al.   Annual Review of Psychology

Diversification of importin-α isoforms in cellular trafficking and disease states

(2015) Ruth A. Pumroy et al.   BIOCHEMICAL JOURNAL

CCL11 enhances excitotoxic neuronal death by producing reactive oxygen species in microglia

(2015) Bijay Parajuli et al.   GLIA

Macromolecular transport in synapse to nucleus communication

(2015) Nicolas Panayotis et al.   TRENDS IN NEUROSCIENCES

Systematic Review of the Neurobiological Relevance of Chemokines to Psychiatric Disorders

(2015) Michael J. Stuart et al.   Frontiers in Cellular Neuroscience

Dynamics and Correlation of Serum Cortisol and Corticosterone under Different Physiological or Stressful Conditions in Mice

(2015) Shuai Gong et al.   PLoS One

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Investigation of rare variants in LRP1, KPNA1, ALS2CL and ZNF480 genes in schizophrenia patients reflects genetic heterogeneity of the disease

(2013) Loubna Jouan et al.   Behavioral and Brain Functions

Importin Alpha Subtypes Determine Differential Transcription Factor Localization in Embryonic Stem Cells Maintenance

(2013) Noriko Yasuhara et al.   DEVELOPMENTAL CELL

KPNA3Variation Is Associated with Schizophrenia, Major Depression, Opiate Dependence and Alcohol Dependence

(2013) Charles P. Morris et al.   DISEASE MARKERS

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Distinct Roles of Segregated Transmission of the Septo-Habenular Pathway in Anxiety and Fear

(2013) Takashi Yamaguchi et al.   NEURON

Adolescent Stress-Induced Epigenetic Control of Dopaminergic Neurons via Glucocorticoids

(2013) M. Niwa et al.   SCIENCE

Corticosterone rapidly increases thorns of CA3 neurons via synaptic/extranuclear glucocorticoid receptor in rat hippocampus

(2013) Miyuki Yoshiya et al.   Frontiers in Neural Circuits

Different changes in cortical tumor necrosis factor-α-related pathways in schizophrenia and mood disorders

(2012) B Dean et al.   MOLECULAR PSYCHIATRY

Convergent Findings for Abnormalities of the NF-κB Signaling Pathway in Schizophrenia

(2012) Panos Roussos et al.   NEUROPSYCHOPHARMACOLOGY

Nuclear retention of importin α coordinates cell fate through changes in gene expression

(2011) Yoshinari Yasuda et al.   EMBO JOURNAL

Targeted disruption of one of the importin α family members leads to female functional incompetence in delivery

(2011) Tetsuji Moriyama et al.   FEBS Journal

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Increased exonic de novo mutation rate in individuals with schizophrenia

(2011) Simon L Girard et al.   NATURE GENETICS

Increased expression of receptor phosphotyrosine phosphatase-β/ζ is associated with molecular, cellular, behavioral and cognitive schizophrenia phenotypes

(2011) N Takahashi et al.   Translational Psychiatry

Individual differences in the elevated plus-maze and the forced swim test

(2010) Celio Estanislau et al.   BEHAVIOURAL PROCESSES

Vulnerability in early life to changes in the rearing environment plays a crucial role in the aetiopathology of psychiatric disorders

(2010) Minae Niwa et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Review: A systematic review of hypothalamic-pituitary-adrenal axis function in schizophrenia: implications for mortality

(2010) Andrew J Bradley et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The environment and schizophrenia

(2010) Jim van Os et al.   NATURE

Distinct Roles of Synaptic Transmission in Direct and Indirect Striatal Pathways to Reward and Aversive Behavior

(2010) Takatoshi Hikida et al.   NEURON

Plasma Protein Biomarkers for Depression and Schizophrenia by Multi Analyte Profiling of Case-Control Collections

(2010) Enrico Domenici et al.   PLoS One

Migration, Ethnicity, and Psychosis: Toward a Sociodevelopmental Model

(2010) C. Morgan et al.   SCHIZOPHRENIA BULLETIN

Prepulse inhibition and genetic mouse models of schizophrenia

(2009) Susan B. Powell et al.   BEHAVIOURAL BRAIN RESEARCH

Object recognition memory and the rodent hippocampus

(2009) N. J. Broadbent et al.   LEARNING & MEMORY

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors

(2009) Gretchen L. Hermes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regional distribution of importin subtype mRNA expression in the nervous system: Study of early postnatal and adult mouse

(2008) K. Hosokawa et al.   NEUROSCIENCE

Antipsychotic-Induced Hyperprolactinemia

(2008) Jolene R Bostwick et al.   PHARMACOTHERAPY

Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions

(2008) J. van Os et al.   SCHIZOPHRENIA BULLETIN