Chrysin inhibits hepatocellular carcinoma progression through suppressing programmed death ligand 1 expression

Antineoplastic Activity of Chrysin against Human Hepatocellular Carcinoma: New Insight on GPC3/SULF2 Axis and lncRNA-AF085935 Expression

(2020) Iman O. Sherif et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chrysin-induced ERK1/2 Phosphorylation Enhances the Sensitivity of Human Hepatocellular Carcinoma Cells to Sorafenib

(2019) CHING-TING WEI et al.   ANTICANCER RESEARCH

PD-1/PD-L1 in disease

(2018) Nyanbol Kuol et al.   Immunotherapy

Association of PD-L1 and HIF-1α Coexpression with Poor Prognosis in Hepatocellular Carcinoma

(2018) Xiaomeng Dai et al.   Translational Oncology

Green Tea Catechin Is an Alternative Immune Checkpoint Inhibitor that Inhibits PD-L1 Expression and Lung Tumor Growth

(2018) Anchalee Rawangkan et al.   MOLECULES

New windows open for immunotherapy in lung cancer

(2018) Lizza Hendriks et al.   NATURE

Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects

(2018) Lu Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Immunomodulatory potential of hesperetin and chrysin through the cellular and humoral response

(2017) Aïcha Sassi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy

(2017) Jingying Zhou et al.   GUT

Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2

(2017) Dong Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MUC1-C integrates PD-L1 induction with repression of immune effectors in non-small-cell lung cancer

(2017) A Bouillez et al.   ONCOGENE

DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

(2017) Hiro Sato et al.   Nature Communications

Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB

(2017) Junli Xue et al.   Oncotarget

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

(2017) Angel Garcia-Diaz et al.   Cell Reports

Apigenin inhibits the inducible expression of programmed death ligand 1 by human and mouse mammary carcinoma cells

(2016) Melanie R. Power Coombs et al.   CANCER LETTERS

Anti-PD-L1 treatment enhances antitumor effect of everolimus in a mouse model of renal cell carcinoma

(2016) Yukiyoshi Hirayama et al.   CANCER SCIENCE

Chrysin, Abundant in Morinda citrifolia Fruit Water–EtOAc Extracts, Combined with Apigenin Synergistically Induced Apoptosis and Inhibited Migration in Human Breast and Liver Cancer Cells

(2016) Cheng Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

(2016) Weiping Zou et al.   Science Translational Medicine

Chrysin induces cell apoptosis via activation of the p53/Bcl-2/caspase-9 pathway in hepatocellular carcinoma cells

(2016) QINGYU ZHANG et al.   Experimental and Therapeutic Medicine

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

(2016) Chia-Wei Li et al.   Nature Communications

BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression

(2016) Hengrui Zhu et al.   Cell Reports

Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies

(2015) J. Naidoo et al.   ANNALS OF ONCOLOGY

Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor- B to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer

(2015) J. Peng et al.   CANCER RESEARCH

Current concepts of immune based treatments for patients with HCC: from basic science to novel treatment approaches

(2015) Tim F Greten et al.   GUT

Chrysin inhibits cell invasion by inhibition of Recepteur d’origine Nantais via suppressing early growth response-1 and NF-κB transcription factor activities in gastric cancer cells

(2015) YONG XIA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Chrysin suppresses human CD14+ monocyte-derived dendritic cells and ameliorates experimental autoimmune encephalomyelitis

(2015) Kai Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives

(2015) Eshvendar Reddy Kasala et al.   TOXICOLOGY LETTERS

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

(2015) Wenfeng Fang et al.   Oncotarget

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Chrysin attenuates experimental autoimmune neuritis by suppressing immuno-inflammatory responses

(2014) J. Xiao et al.   NEUROSCIENCE

PD-L1 Expression Is Increased in a Subset of Basal Type Breast Cancer Cells

(2014) Hatem Soliman et al.   PLoS One

Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway

(2013) Ai-Mei Gao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Spontaneous regression of hepatocellular carcinoma is most often associated with tumour hypoxia or a systemic inflammatory response

(2012) Jonathan I. Huz et al.   HPB

Expression of B7-H1 protein in human pancreatic carcinoma tissues and its clinical significance

(2012) Xiao-Ling Chen et al.   Chinese Journal of Cancer

Chrysin protects mice from Staphylococcus aureus pneumonia

(2011) J. Wang et al.   JOURNAL OF APPLIED MICROBIOLOGY

Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma

(2009) Q. Gao et al.   CLINICAL CANCER RESEARCH

Triptolide inhibits interferon-γ-induced programmed death-1-ligand 1 surface expression in breast cancer cells

(2008) Mei Liang et al.   CANCER LETTERS