Berberine Improves the Protective Effects of Metformin on Diabetic Nephropathy in db/db Mice through Trib1-dependent Inhibiting Inflammation

Trib1 Contributes to Recovery From Ischemia/Reperfusion-Induced Acute Kidney Injury by Regulating the Polarization of Renal Macrophages

(2020) Xiangcheng Xie et al.   Frontiers in Immunology

Notoginsenoside R1 Protects db/db Mice against Diabetic Nephropathy via Upregulation of Nrf2-Mediated HO-1 Expression

(2019) Bin Zhang et al.   MOLECULES

Diabetic nephropathy: recent advances in pathophysiology and challenges in dietary management

(2019) Mahaboob Khan Sulaiman   Diabetology & Metabolic Syndrome

Antidiabetic and Cardioprotective Effects of Pharmacological Inhibition of GRK2 in db/db Mice

(2019) Ersilia Cipolletta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-155 Mediates Obesity-Induced Renal Inflammation and Dysfunction

(2019) Chenfei Zheng et al.   INFLAMMATION

Kidney Injury Molecule-1 Is Upregulated in Renal Lipotoxicity and Mediates Palmitate-Induced Tubular Cell Injury and Inflammatory Response

(2019) Xueying Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Activity and Skeletal Muscle Insulin Resistance in Kidney Disease

(2019) Jane E. Carré et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK–NF-κB signaling mediated inflammation

(2019) Jingjing Ben et al.   Nature Communications

Mitochondrial dysfunction in diabetic kidney disease

(2019) Pascal Zhongping Wei et al.   CLINICA CHIMICA ACTA

Vitamin D receptor activation in liver macrophages ameliorates hepatic inflammation, steatosis, and insulin resistance in mice

(2019) Bingning Dong et al.   HEPATOLOGY

QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice

(2019) Xiangming Wang et al.   Frontiers in Physiology

Metformin can alleviate the symptom of patient with diabetic nephropathy through reducing the serum level of Hcy and IL-33

(2019) Ling Zhang et al.   Open Medicine

Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice

(2019) Shu Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-Diabetic Nephropathy Activities of Polysaccharides Obtained from Termitornyces albuminosus via Regulation of NF-κB Signaling in db/db Mice

(2019) Chang Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Berberine decreases plasma triglyceride levels and upregulates hepatic TRIB1 in LDLR wild type mice and in LDLR deficient mice

(2019) Amar Bahadur Singh et al.   Scientific Reports

Gold nanoparticles attenuate albuminuria by inhibiting podocyte injury in a rat model of diabetic nephropathy

(2019) Ghada Alomari et al.   Drug Delivery and Translational Research

Metformin alleviates renal injury in diabetic rats by inducing Sirt1/FoxO1 autophagic signal axis

(2019) Jiang Xu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury

(2019) Zhaopeng Yan et al.   LIFE SCIENCES

Kidney protection effects of dihydroquercetin on diabetic nephropathy through suppressing ROS and NLRP3 inflammasome

(2018) Tao Ding et al.   PHYTOMEDICINE

Nyctanthes arbor-tristis leaf extract ameliorates hyperlipidemia- and hyperglycemia-associated nephrotoxicity by improving anti-oxidant and anti-inflammatory status in high-fat diet–streptozotocin-induced diabetic rats

(2018) Sayed Adam Mousum et al.   INFLAMMOPHARMACOLOGY

NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice

(2018) Ming Wu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy

(2018) Wei Wei et al.   Scientific Reports

Elimination of Age-Associated Hepatic Steatosis and Correction of Aging Phenotype by Inhibition of cdk4-C/EBPα-p300 Axis

(2018) Phuong Nguyen et al.   Cell Reports

Targeting inflammation in diabetic nephropathy: a tale of hope

(2018) Juan Antonio Moreno et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Combination of Berberine with Resveratrol Improves the Lipid-Lowering Efficacy

(2018) Xiaofei Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling

(2018) Bin Zhang et al.   Frontiers in Pharmacology

Dibenzoylmethane ameliorates lipid-induced inflammation and oxidative injury in diabetic nephropathy

(2018) Eun Soo Lee et al.   JOURNAL OF ENDOCRINOLOGY

Advanced glycation end products (AGEs) increase renal lipid accumulation: a pathogenic factor of diabetic nephropathy (DN)

(2017) Yang Yuan et al.   Lipids in Health and Disease

Complement C5a inhibition moderates lipid metabolism and reduces tubulointerstitial fibrosis in diabetic nephropathy

(2017) Wai Han Yiu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

miR-192-5p regulates lipid synthesis in non-alcoholic fatty liver disease through SCD-1

(2017) Xiao-Lin Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Renoprotective effect of DPP-4 inhibitors against free fatty acid-bound albumin-induced renal proximal tubular cell injury

(2016) Yuki Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metformin Activates AMPK through the Lysosomal Pathway

(2016) Chen-Song Zhang et al.   Cell Metabolism

Trends in Chronic Kidney Disease in China

(2016) Luxia Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dysregulation of low-density lipoprotein receptor contributes to podocyte injuries in diabetic nephropathy

(2015) Yang Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα

(2015) Robert C. Bauer et al.   JOURNAL OF CLINICAL INVESTIGATION

Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes

(2015) Cristina Martínez-García et al.   PLoS One

Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats

(2014) Amal Hofni et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TRIB1 downregulates hepatic lipogenesis and glycogenesis via multiple molecular interactions

(2014) Yuumi Ishizuka et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

(2013) Takashi Satoh et al.   NATURE

The role of the podocyte in albumin filtration

(2013) Paul Thomas Brinkkoetter et al.   Nature Reviews Nephrology

Inflammation and the pathogenesis of diabetic nephropathy

(2012) Jun Wada et al.   CLINICAL SCIENCE

C/EBP , C/EBP  Oncoproteins, or C/EBP  Preferentially Bind NF- B p50 Compared with p65, Focusing Therapeutic Targeting on the C/EBP:p50 Interaction

(2011) J. E. Dooher et al.   MOLECULAR CANCER RESEARCH

Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/−Mice: A Role of Lipid Mobilization and Inflammation

(2010) Fen Xu et al.   ENDOCRINOLOGY

Trib1 is a lipid- and myocardial infarction–associated gene that regulates hepatic lipogenesis and VLDL production in mice

(2010) Ralph Burkhardt et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathologic Classification of Diabetic Nephropathy

(2010) T. W. C. Tervaert et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fatty Acid-Bearing Albumin Induces VCAM-1 Expression through c-Src Kinase-AP-1/NF-ĸB Pathways: Effect ofL-Carnitine

(2010) Joo Eun Baek et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Diabetic nephropathy—challenges in pathologic classification

(2010) Paola Fioretto et al.   Nature Reviews Nephrology

NF- B p50 Regulates C/EBP  Expression and Inflammatory Cytokine-Induced Neutrophil Production

(2009) D. Wang et al.   JOURNAL OF IMMUNOLOGY

Tribbles-1 as a Novel Biomarker of Chronic Antibody-Mediated Rejection

(2008) J. Ashton-Chess et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prevalence of albuminuria and renal insufficiency and associated clinical factors in type 2 diabetes: the Japan Diabetes Clinical Data Management study (JDDM15)

(2008) H. Yokoyama et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION