Jinlida granules ameliorate the high-fat-diet induced liver injury in mice by antagonising hepatocytes pyroptosis

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

(2020) Susanne Gaul et al.   JOURNAL OF HEPATOLOGY

Basis and Design of a Randomized Clinical Trial to Evaluate the Effect of Jinlida Granules on Metabolic Syndrome in Patients With Abnormal Glucose Metabolism

(2020) De Jin et al.   Frontiers in Endocrinology

Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis

(2019) Ping Zhou et al.   Cells

Optimizing Use of Nonalcoholic Fatty Liver Disease Fibrosis Score, Fibrosis-4 Score, and Liver Stiffness Measurement to Identify Patients with Advanced Fibrosis

(2019) Wah-Kheong Chan et al.   Clinical Gastroenterology and Hepatology

Chinese medicine Jinlida granules improve high-fat-diet induced metabolic disorders via activation of brown adipose tissue in mice

(2019) Hui Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress

(2019) Zheng Lyu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Emerging Molecular Targets for Treatment of Nonalcoholic Fatty Liver Disease

(2019) Ze Chen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Combined Use of Astragalus Polysaccharide and Berberine Attenuates Insulin Resistance in IR-HepG2 Cells via Regulation of the Gluconeogenesis Signaling Pathway

(2019) Zhu-Jun Mao et al.   Frontiers in Pharmacology

Repurposing matrine for the treatment of hepatosteatosis and associated disorders in glucose homeostasis in mice

(2018) Ali Mahzari et al.   ACTA PHARMACOLOGICA SINICA

Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease

(2018) Juan Pablo Arab et al.   Annual Review of Pathology-Mechanisms of Disease

Triterpenic acids-enriched fraction from Cyclocarya paliurus attenuates non-alcoholic fatty liver disease via improving oxidative stress and mitochondrial dysfunction

(2018) Meng-ge Zhao et al.   BIOMEDICINE & PHARMACOTHERAPY

Genipin Reverses HFD-Induced Liver Damage and Inhibits UCP2-Mediated Pyroptosis in Mice

(2018) Hong Zhong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effectiveness of traditional Chinese medicine Jinlida granules as an add-on therapy for type 2 diabetes: A system review and meta-analysis of randomized controlled trials

(2018) Fengmei Lian et al.   Journal of Diabetes

Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine

(2017) Meifeng Liu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

New trends on obesity and NAFLD in Asia

(2017) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY

A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis

(2017) Jurema Schmidt et al.   JOURNAL OF MEDICINAL CHEMISTRY

Deficiency of the Purinergic Receptor 2X7 Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome

(2017) Claudia Blasetti Fantauzzi et al.   Oxidative Medicine and Cellular Longevity

Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis

(2017) Jinghua Du et al.   Theranostics

Evaluation of the Chinese herbal medicine Jinlida in type 2 diabetes patients based on stratification: Results of subgroup analysis from a 12-week trial

(2017) Jiaxing Tian et al.   Journal of Diabetes

Original Research: Potential ocular protection and dynamic observation of Polygonatum sibiricum polysaccharide against streptozocin-induced diabetic rats’ model

(2016) Yi Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Global epidemiology of nonalcoholic fatty liver disease: Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) A. Lonardo et al.   HEPATOLOGY

A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet

(2016) Gabsik Yang et al.   Scientific Reports

Association of nonalcoholic fatty liver disease (NAFLD) with hepatocellular carcinoma (HCC) in the United States from 2004 to 2009

(2015) Zobair M. Younossi et al.   HEPATOLOGY

Jinlida granule inhibits palmitic acid induced-intracellular lipid accumulation and enhances autophagy in NIT-1 pancreatic β cells through AMPK activation

(2015) Dingkun Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Jinlida reduces insulin resistance and ameliorates liver oxidative stress in high-fat fed rats

(2015) Yixuan Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management

(2015) Stuart McPherson et al.   JOURNAL OF HEPATOLOGY

The Efficacy and Safety of Chinese Herbal Medicine Jinlida as Add-On Medication in Type 2 Diabetes Patients Ineffectively Managed by Metformin Monotherapy: A Double-Blind, Randomized, Placebo-Controlled, Multicenter Trial

(2015) Fengmei Lian et al.   PLoS One

Hypoglycemic and hypolipidemic effects of oxymatrine in high-fat diet and streptozotocin-induced diabetic rats

(2014) Changrun Guo et al.   PHYTOMEDICINE

Anti-hyperglycemic and anti-oxidative activities of ginseng polysaccharides in STZ-induced diabetic mice

(2014) Chengxin Sun et al.   Food & Function

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Inflammasomes and Their Roles in Health and Disease

(2012) Mohamed Lamkanfi et al.   Annual Review of Cell and Developmental Biology

Saponin rich fractions from Polygonatum odoratum (Mill.) Druce with more potential hypoglycemic effects

(2012) Yafei Deng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

Effect and Mechanism of Ginsenosides CK and Rg1 on Stimulation of Glucose Uptake in 3T3-L1 Adipocytes

(2010) Yu-Chuan Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease

(2010) Zoltan Derdak et al.   JOURNAL OF HEPATOLOGY