Empagliflozin Enhances Autophagy, Mitochondrial Biogenesis, and Antioxidant Defense and Ameliorates Renal Ischemia/Reperfusion in Nondiabetic Rats

Pathophysiology of diabetic kidney disease: impact of SGLT2 inhibitors

(2021) Ralph A. DeFronzo et al.   Nature Reviews Nephrology

Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function

(2021) Moein Ala et al.   Oxidative Medicine and Cellular Longevity

Renal protective effect of nebivolol in rat models of acute renal injury: role of sodium glucose co-transporter 2

(2020) Ahmed M. Nasr et al.   Pharmacological Reports

Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet–Induced Obese Mice

(2020) Xiaodong Sun et al.   DIABETES

SGLT2 Inhibitor Empagliflozin and DPP4 Inhibitor Linagliptin Reactivate Glomerular Autophagy in db/db Mice, a Model of Type 2 Diabetes

(2020) Anton I. Korbut et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Empagliflozin attenuates acute kidney injury after myocardial infarction in diabetic rats

(2020) Atsushi Kuno et al.   Scientific Reports

Role of ketogenic starvation sensors in mediating the renal protective effects of SGLT2 inhibitors in type 2 diabetes

(2020) Milton Packer   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Theaflavin ameliorates renal ischemia/reperfusion injury by activating the Nrf2 signalling pathway in vivo and in vitro

(2020) Zhongyuan Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective effect of hyperoside against renal ischemia-reperfusion injury via modulating mitochondrial fission, oxidative stress and apoptosis

(2019) Lin Wu et al.   FREE RADICAL RESEARCH

PGC‐1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

(2019) Miguel Fontecha‐Barriuso et al.   JOURNAL OF PATHOLOGY

The Role of Oxidative Stress, Renal Inflammation, and Apoptosis in Post Ischemic Reperfusion Injury of Kidney Tissue: the Protective Effect of Dose-Dependent Boric Acid Administration

(2019) Fatih Kar et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Sodium-glucose cotransporter 2 (SGLT-2) inhibitors and microvascular outcomes in patients with type 2 diabetes: systematic review and meta-analysis

(2019) E. G. Dorsey-Treviño et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Acute kidney injury and adverse renal events in patients receiving SGLT2-inhibitors: A systematic review and meta-analysis

(2019) Jan Menne et al.   PLOS MEDICINE

Effects of the SGLT-2 inhibitor dapagliflozin on glomerular and tubular injury markers

(2018) Claire C. J. Dekkers et al.   DIABETES OBESITY & METABOLISM

Mitochondrial dysfunction in diabetic kidney disease

(2018) Josephine M. Forbes et al.   Nature Reviews Nephrology

Influence of autophagy on acute kidney injury in a murine cecal ligation and puncture sepsis model

(2018) Satoshi Sunahara et al.   Scientific Reports

Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression

(2017) Masahiro Nezu et al.   KIDNEY INTERNATIONAL

Autophagy is activated to protect against endotoxic acute kidney injury

(2016) Shuqin Mei et al.   Scientific Reports

The Effect of Autophagy on Inflammation Cytokines in Renal Ischemia/Reperfusion Injury

(2015) Haibin Ling et al.   INFLAMMATION

Acute kidney injury: an increasing global concern

(2013) Norbert H Lameire et al.   LANCET

Augmenting Autophagy to Treat Acute Kidney Injury during Endotoxemia in Mice

(2013) Gina M. Howell et al.   PLoS One

SGLT-2 inhibitors and their potential in the treatment of diabetes

(2013) Benjamin Epstein et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

(2012) Atsushi Takahashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

Acute kidney injury

(2012) Rinaldo Bellomo et al.   LANCET

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

(2011) Mei Tran et al.   JOURNAL OF CLINICAL INVESTIGATION

Malondialdehyde in Exhaled Breath Condensate as a Marker of Oxidative Stress in Different Pulmonary Diseases

(2011) M. L. Bartoli et al.   MEDIATORS OF INFLAMMATION

Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice

(2009) Manchang Liu et al.   KIDNEY INTERNATIONAL