Electrocatalysis as a key strategy for the total synthesis of natural products

Electrochemical Total Synthesis of Pyrrolophenanthridone Alkaloids: Controlling the Anodically Initiated Electron Transfer Process

(2020) Kazuhiro Okamoto et al.   ORGANIC LETTERS

Electrochemical Oxidation of Δ9-Tetrahydrocannabinol: A Simple Strategy for Marijuana Detection

(2020) Evan R. Darzi et al.   ORGANIC LETTERS

Brucine: A Review of Phytochemistry, Pharmacology, and Toxicology

(2020) Lu Lu et al.   Frontiers in Pharmacology

Electrochemical N-Demethylation of 14-Hydroxy Morphinans: Sustainable Access to Opioid Antagonists

(2020) Gabriel Glotz et al.   ORGANIC LETTERS

11-Step Total Synthesis of Teleocidins B-1–B-4

(2019) Hugh Nakamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (−)-Oxycodone via Anodic Aryl–Aryl Coupling

(2019) Alexander Lipp et al.   ORGANIC LETTERS

A Regio- and Diastereoselective Anodic Aryl-Aryl Coupling in the Biomimetic Total Synthesis of (−)-Thebaine

(2018) Alexander Lipp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu(ii)–tBu–PHOX catalyzed enantioselective malonate addition onto 3-hydroxy 2-oxindoles: application in the synthesis of dimeric pyrroloindoline alkaloids

(2018) K. Naresh Babu et al.   CHEMICAL COMMUNICATIONS

Electrochemical strategies for C–H functionalization and C–N bond formation

(2018) Markus D. Kärkäs   CHEMICAL SOCIETY REVIEWS

Recent Advances in Organic Electrochemical C-H Functionalization

(2018) Qi-Liang Yang et al.   CHINESE JOURNAL OF CHEMISTRY

Complex Organic Synthesis: Structure, Properties, and/or Function?

(2018) George M. Whitesides   ISRAEL JOURNAL OF CHEMISTRY

Electrochemical Formation of N-Acyloxy Amidyl Radicals and Their Application: Regioselective Intramolecular Amination of sp2 and sp3 C–H Bonds

(2018) Sheng Zhang et al.   ORGANIC LETTERS

Electrocatalytic C–H Activation

(2018) Nicolas Sauermann et al.   ACS Catalysis

Recent Advances in C–H Functionalization Using Electrochemical Transition Metal Catalysis

(2018) Cong Ma et al.   ACS Catalysis

Thiourea-Catalyzed Enantioselective Malonate Addition onto 3-Sulfonyl-3′-indolyl-2-oxindoles: Formal Total Syntheses of (−)-Chimonanthine, (−)-Folicanthine, and (+)-Calycanthine

(2018) K. Naresh Babu et al.   ORGANIC LETTERS

Photocatalysis in Organic Synthesis - Past, Present, and Future

(2017) Burkhard König   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Efficient, selective and sustainable catalysis of carbon dioxide

(2017) Qing-Wen Song et al.   GREEN CHEMISTRY

Scalable, Electrochemical Oxidation of Unactivated C–H Bonds

(2017) Yu Kawamata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalyst: Sustainable Catalysis

(2017) Jacob R. Ludwig et al.   Chem

The merger of transition metal and photocatalysis

(2017) Jack Twilton et al.   Nature Reviews Chemistry

Synthetic Applications of Proton-Coupled Electron Transfer

(2016) Emily C. Gentry et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cascade polycyclizations in natural product synthesis

(2016) R. Ardkhean et al.   CHEMICAL SOCIETY REVIEWS

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

Phytocannabinoids: a unified critical inventory

(2016) Lumír Ondřej Hanuš et al.   NATURAL PRODUCT REPORTS

Scalable and sustainable electrochemical allylic C–H oxidation

(2016) Evan J. Horn et al.   NATURE

Electochemical asymmetric dimerization of cinnamic acid derivatives and application to the enantioselective syntheses of furofuran lignans

(2016) Naoki Mori et al.   TETRAHEDRON

Pot economy and one-pot synthesis

(2016) Yujiro Hayashi   Chemical Science

Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method

(2016) Evan J. Horn et al.   ACS Central Science

Photoredox Catalysis Unlocks Single-Electron Elementary Steps in Transition Metal Catalyzed Cross-Coupling

(2016) Mark D. Levin et al.   ACS Central Science

Electrolytic Macrocyclizations: Scalable Synthesis of a Diazonamide-Based Drug Development Candidate

(2015) Hui Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal Catalysis and Organocatalysis: Where Can Progress Be Expected?

(2015) Qi-Lin Zhou   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reinventing Chemistry

(2015) George M. Whitesides   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper catalyzed sequential arylation−oxidative dimerization of o-haloanilides: synthesis of dimeric HPI alkaloids

(2015) Xianfu Shen et al.   CHEMICAL COMMUNICATIONS

Discovery of Novel Synthetic Methodologies and Reagents during Natural Product Synthesis in the Post-Palytoxin Era

(2015) Ahlam M. Armaly et al.   CHEMICAL REVIEWS

Catalytic Enantioselective Decarboxylative Allylations of a Mixture of Allyl Carbonates and Allyl Esters: Total Synthesis of (−)- and (+)-Folicanthine

(2015) Santanu Ghosh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Closing the loop: captured CO2 as a feedstock in the chemical industry

(2015) Alexander Otto et al.   Energy & Environmental Science

Automated Electrochemical Assembly of the Protected Potential TMG-chitotriomycin Precursor Based on Rational Optimization of the Carbohydrate Building Block

(2015) Toshiki Nokami et al.   ORGANIC LETTERS

Using carbon dioxide as a building block in organic synthesis

(2015) Qiang Liu et al.   Nature Communications

Total Synthesis of Dixiamycin B by Electrochemical Oxidation

(2014) Brandon R. Rosen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expedient Preparation of Nazlinine and a Small Library of Indole Alkaloids Using Flow Electrochemistry as an Enabling Technology

(2014) Mikhail A. Kabeshov et al.   ORGANIC LETTERS

Elucidating the Cyclization Cascades in Xiamycin Biosynthesis by Substrate Synthesis and Enzyme Characterizations

(2014) Huixian Li et al.   ORGANIC LETTERS

Enantioselective construction of vicinal all-carbon quaternary centers via catalytic double asymmetric decarboxylative allylation

(2013) Santanu Ghosh et al.   CHEMICAL COMMUNICATIONS

Expeditious Approach to Pyrrolophenanthridones, Phenanthridines, and Benzo[c]phenanthridines via Organocatalytic Direct Biaryl-Coupling Promoted by Potassium tert-Butoxide

(2013) Subhadip De et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent Developments in the Catalytic, Asymmetric Construction of Pyrroloindolines Bearing All-Carbon Quaternary Stereocenters

(2013) Lindsay M. Repka et al.   JOURNAL OF ORGANIC CHEMISTRY

Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future

(2013) Manfred T. Reetz   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Automated Solution-Phase Synthesis of Oligosaccharides via Iterative Electrochemical Assembly of Thioglycosides

(2013) Toshiki Nokami et al.   ORGANIC LETTERS

Antitumour activities of sanguinarine and related alkaloids

(2013) Iva Slaninová et al.   PHYTOCHEMISTRY REVIEWS

Anodic Oxidation on a Boron-Doped Diamond Electrode Mediated by Methoxy Radicals

(2012) Takenori Sumi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification and Characterization of Xiamycin A and Oxiamycin Gene Cluster Reveals an Oxidative Cyclization Strategy Tailoring Indolosesquiterpene Biosynthesis

(2012) Huixian Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Intramolecular Direct Dehydrohalide Coupling Promoted by KOtBu: Total Synthesis of Amaryllidaceae Alkaloids Anhydrolycorinone and Oxoassoanine

(2012) Subhadip De et al.   ORGANIC LETTERS

Glycosyl Sulfonium Ions as Storable Intermediates for Glycosylations

(2011) Toshiki Nokami et al.   ORGANIC LETTERS

Organic electrosynthesis: a promising green methodology in organic chemistry

(2010) Bernardo A. Frontana-Uribe et al.   GREEN CHEMISTRY

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

α- and β-Glycosyl Sulfonium Ions: Generation and Reactivity

(2009) Toshiki Nokami et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesizing our future

(2009) Ryoji Noyori   Nature Chemistry

Protecting-group-free synthesis as an opportunity for invention

(2009) Ian S. Young et al.   Nature Chemistry

Synthesis of Tetrahydropyrroloiminoquinone Alkaloids Based on Electrochemically Generated Hypervalent Iodine Oxidative Cyclization

(2009) Keisuke Inoue et al.   ORGANIC LETTERS

Redox Electron-Transfer Reactions: Electrochemically Mediated Rearrangement, Mechanism, and a Total Synthesis of Daucene

(2008) Young Sam Park et al.   JOURNAL OF ORGANIC CHEMISTRY

TMG-chitotriomycin, an Enzyme Inhibitor Specific for Insect and Fungal β-N-Acetylglucosaminidases, Produced by ActinomyceteStreptomyces anulatusNBRC 13369

(2008) Hirokazu Usuki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Green chemistry for chemical synthesis

(2008) C.-J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA