STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway
出版年份 2021 全文链接
标题
STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway
作者
关键词
-
出版物
ONCOGENE
Volume 40, Issue 49, Pages 6627-6640
出版商
Springer Science and Business Media LLC
发表日期
2021-10-08
DOI
10.1038/s41388-021-02037-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Human DNA-PK activates a STING-independent DNA sensing pathway
- (2020) Katelyn Burleigh et al. Science Immunology
- The cGAS/STING/TBK1/IRF3 innate immunity pathway maintains chromosomal stability through regulation of p21 levels
- (2020) Abdul Basit et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- cGAS suppresses genomic instability as a decelerator of replication forks
- (2020) Hao Chen et al. Science Advances
- Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
- (2019) Guijun Shang et al. NATURE
- Correction: Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents
- (2019) Julie Gaston et al. Oncotarget
- DNA-PK as an Emerging Therapeutic Target in Cancer
- (2019) Ismail S. Mohiuddin et al. Frontiers in Oncology
- Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death
- (2019) Hui Jiang et al. EMBO JOURNAL
- The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer
- (2018) Tuo Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
- (2018) Hiroyasu Konno et al. ONCOGENE
- The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment
- (2018) Samuel F. Bakhoum et al. CELL
- Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
- (2018) Gillian Dunphy et al. MOLECULAR CELL
- STING promotes homeostasis via regulation of cell proliferation and chromosomal stability
- (2018) Diana Rose E. Ranoa et al. CANCER RESEARCH
- Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
- (2018) Haipeng Liu et al. NATURE
- A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1
- (2017) Erkin Erdal et al. GENES & DEVELOPMENT
- p38 inhibition provides anti–DNA virus immunity by regulation of USP21 phosphorylation and STING activation
- (2017) Yunfei Chen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination
- (2017) Thomas L. Clarke et al. MOLECULAR CELL
- ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
- (2017) Andrew N. Blackford et al. MOLECULAR CELL
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- cGAS is essential for the antitumor effect of immune checkpoint blockade
- (2017) Hua Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA
- (2017) Hongyan Sui et al. Science Signaling
- DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
- (2017) Claire Vanpouille-Box et al. Nature Communications
- Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response
- (2017) Vijay K. Gonugunta et al. Cell Reports
- STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA
- (2017) Hongyan Sui et al. Science Signaling
- Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis
- (2016) Tianli Xia et al. CANCER RESEARCH
- Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
- (2016) Eileen E. Parkes et al. JNCI-Journal of the National Cancer Institute
- Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
- (2016) Qing Chen et al. NATURE
- Decreased Expression of TMEM173 Predicts Poor Prognosis in Patients with Hepatocellular Carcinoma
- (2016) Yang Bu et al. PLoS One
- Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents
- (2016) Julie Gaston et al. Oncotarget
- Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
- (2016) Tianli Xia et al. Cell Reports
- Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
- (2016) Eileen E. Parkes et al. JNCI-Journal of the National Cancer Institute
- The nuclear lamina in health and disease
- (2016) Agnieszka Dobrzynska et al. Nucleus
- The nuclear lamina in health and disease
- (2016) Agnieszka Dobrzynska et al. Nucleus
- Activated STING enhances Tregs infiltration in the HPV-related carcinogenesis of tongue squamous cells via the c-jun/CCL22 signal
- (2015) Ding Liang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer
- (2015) Marie-Emmanuelle Legrier et al. BRITISH JOURNAL OF CANCER
- Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors
- (2015) J. R. Baird et al. CANCER RESEARCH
- DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
- (2015) Anetta Härtlova et al. IMMUNITY
- Interferon α/β Enhances the Cytotoxic Response of MEK Inhibition in Melanoma
- (2015) Oren Litvin et al. MOLECULAR CELL
- Heterochromatic breaks move to the nuclear periphery to continue recombinational repair
- (2015) Taehyun Ryu et al. NATURE CELL BIOLOGY
- PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
- (2015) T. Ochi et al. SCIENCE
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- Nuclear position dictates DNA repair pathway choice
- (2014) Charlène Lemaître et al. GENES & DEVELOPMENT
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- An Alternative Splicing Isoform of MITA Antagonizes MITA-Mediated Induction of Type I IFNs
- (2014) H. Chen et al. JOURNAL OF IMMUNOLOGY
- Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF- B Activation through TBK1
- (2014) T. Abe et al. JOURNAL OF VIROLOGY
- ColonyArea: An ImageJ Plugin to Automatically Quantify Colony Formation in Clonogenic Assays
- (2014) Camilo Guzmán et al. PLoS One
- Copy Number Loss of the Interferon Gene Cluster in Melanomas Is Linked to Reduced T Cell Infiltrate and Poor Patient Prognosis
- (2014) Peter S. Linsley et al. PLoS One
- NET23/STING Promotes Chromatin Compaction from the Nuclear Envelope
- (2014) Poonam Malik et al. PLoS One
- Beyond DNA Repair: DNA-PK Function in Cancer
- (2014) J. F. Goodwin et al. Cancer Discovery
- Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy
- (2014) Yuk Yuen Lan et al. Cell Reports
- High-mobility group box 2 (HMGB2) modulates radioresponse and is downregulated by p53 in colorectal cancer cell
- (2013) Young-Joo Shin et al. CANCER BIOLOGY & THERAPY
- A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
- (2013) Sébastien Britton et al. JOURNAL OF CELL BIOLOGY
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking
- (2013) T. Kondo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Destination: inner nuclear membrane
- (2013) Santharam S. Katta et al. TRENDS IN CELL BIOLOGY
- STING-dependent cytosolic DNA sensing pathways
- (2013) Glen N. Barber TRENDS IN IMMUNOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- ATP-dependent chromatin remodeling in the DNA-damage response
- (2012) Hannes Lans et al. Epigenetics & Chromatin
- DNA-PK is a DNA sensor for IRF-3-dependent innate immunity
- (2012) Brian J Ferguson et al. eLife
- Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity
- (2011) Huihui Chen et al. CELL
- Choosing the right path: Does DNA-PK help make the decision?
- (2011) Jessica A. Neal et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
- (2011) Claudia Lukas et al. NATURE CELL BIOLOGY
- Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope
- (2010) Poonam Malik et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- In situ Subcellular Fractionation of Adherent and Non-adherent Mammalian Cells
- (2010) Anyaporn Sawasdichai et al. Jove-Journal of Visualized Experiments
- Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery
- (2009) P. Oza et al. GENES & DEVELOPMENT
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
- (2009) T. Saitoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
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