In vivo imaging of synaptic density with [11C]UCB-J PET in two mouse models of neurodegenerative disease

Age-related increase of alpha-synuclein oligomers is associated with motor disturbances in L61 transgenic mice

(2021) Sahar Roshanbin et al.   NEUROBIOLOGY OF AGING

Synaptic density in healthy human aging is not influenced by age or sex: a 11C-UCB-J PET study

(2021) Laura Michiels et al.   NEUROIMAGE

Synaptic Changes in Parkinson Disease Assessed with in vivo Imaging

(2020) David Matuskey et al.   ANNALS OF NEUROLOGY

Loss of Presynaptic Terminal Integrity in the Substantia Nigra in Early Parkinson's Disease

(2020) Aline Delva et al.   MOVEMENT DISORDERS

In vivo synaptic density imaging with 11C-UCB-J detects treatment effects of saracatinib (AZD0530) in a mouse model of Alzheimer’s disease.

(2019) Takuya Toyonaga et al.   JOURNAL OF NUCLEAR MEDICINE

Characterization of 3 PET tracers for Quantification of Mitochondrial and Synaptic function in Healthy Human Brain: 18F-BCPP-EF, 11C-SA-4503, 11C-UCB-J

(2019) Ayla Mansur et al.   JOURNAL OF NUCLEAR MEDICINE

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging

(2018) Ming-Kai Chen et al.   JAMA Neurology

Noninvasive Relative Quantification of [11C]ABP688 PET Imaging in Mice Versus an Input Function Measured Over an Arteriovenous Shunt

(2018) Jeroen Verhaeghe et al.   Frontiers in Neurology

Blood-brain barrier integrity in a mouse model of Alzheimer's disease with or without acute 3D6 immunotherapy

(2018) Sofia Gustafsson et al.   NEUROPHARMACOLOGY

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

(2017) Amy R. Dunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β

(2017) Dag Sehlin et al.   Scientific Reports

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

(2016) N. B. Nabulsi et al.   JOURNAL OF NUCLEAR MEDICINE

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

(2016) Jeff Sevigny et al.   NATURE

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice

(2013) Sveinung Lillehaug et al.   NEUROBIOLOGY OF AGING

A Progressive Mouse Model of Parkinson’s Disease: The Thy1-aSyn (“Line 61”) Mice

(2012) Marie-Francoise Chesselet et al.   Neurotherapeutics

Synaptic vesicle trafficking and Parkinson's disease

(2011) Giovanni Esposito et al.   Developmental Neurobiology

Impaired behavior of female tg-ArcSwe APP mice in the IntelliCage: A longitudinal study

(2010) Alina Codita et al.   BEHAVIOURAL BRAIN RESEARCH

SV2 Acts via Presynaptic Calcium to Regulate Neurotransmitter Release

(2010) Qun-Fang Wan et al.   NEURON

Amyloid-β protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice

(2009) Anna Lord et al.   FEBS Journal