Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads
出版年份 2021 全文链接
标题
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads
作者
关键词
-
出版物
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 28, Issue 11, Pages 923-935
出版商
Springer Science and Business Media LLC
发表日期
2021-11-11
DOI
10.1038/s41594-021-00677-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Physics-based computational and theoretical approaches to intrinsically disordered proteins
- (2021) Joan-Emma Shea et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The (un)structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy
- (2020) Anastasia C. Murthy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NMR Experiments for Studies of Dilute and Condensed Protein Phases: Application to the Phase-Separating Protein CAPRIN1
- (2020) Leo E. Wong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
- (2020) Erik W. Martin et al. SCIENCE
- Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior
- (2020) Benjamin S. Schuster et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Explicit Representation of Cation−π Interactions in Force Fields with 1/r4 Nonbonded Terms
- (2020) Aysegul Turupcu et al. Journal of Chemical Theory and Computation
- Unraveling Molecular Interactions in Liquid–Liquid Phase Separation of Disordered Proteins by Atomistic Simulations
- (2020) Matteo Paloni et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Refining All-Atom Protein Force Fields for Polar-Rich, Prion-like, Low-Complexity Intrinsically Disordered Proteins
- (2020) Wai Shing Tang et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Nucleated transcriptional condensates amplify gene expression
- (2020) Ming-Tzo Wei et al. NATURE CELL BIOLOGY
- Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation
- (2019) Brian Tsang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads
- (2019) Feiyue Lu et al. MOLECULAR CELL
- Evolution of All-Atom Protein Force Fields to Improve Local and Global Properties
- (2019) Gül H. Zerze et al. Journal of Physical Chemistry Letters
- Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain
- (2019) Anastasia C. Murthy et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Lysine/RNA-interactions drive and regulate biomolecular condensation
- (2019) Tina Ukmar-Godec et al. Nature Communications
- A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids
- (2019) Jian Kang et al. PLOS BIOLOGY
- Interplay between Short-Range Attraction and Long-Range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein–RNA Complexes
- (2019) Ibraheem Alshareedah et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
- (2019) Yang Eric Guo et al. NATURE
- Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation
- (2019) Tae Hun Kim et al. SCIENCE
- NPM1 exhibits structural and dynamic heterogeneity upon phase separation with the p14ARF tumor suppressor
- (2019) Eric Gibbs et al. JOURNAL OF MAGNETIC RESONANCE
- Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
- (2018) Takuya Yoshizawa et al. CELL
- Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
- (2018) Mario Hofweber et al. CELL
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
- (2018) Seema Qamar et al. CELL
- RGG/RG Motif Regions in RNA Binding and Phase Separation
- (2018) P. Andrew Chong et al. JOURNAL OF MOLECULAR BIOLOGY
- Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation
- (2018) Veronica H. Ryan et al. MOLECULAR CELL
- Imaging dynamic and selective low-complexity domain interactions that control gene transcription
- (2018) Shasha Chong et al. SCIENCE
- Coactivator condensation at super-enhancers links phase separation and gene control
- (2018) Benjamin R. Sabari et al. SCIENCE
- Mediator and RNA polymerase II clusters associate in transcription-dependent condensates
- (2018) Won-Ki Cho et al. SCIENCE
- Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity
- (2018) Elke Bogaert et al. Cell Reports
- Sequence determinants of protein phase behavior from a coarse-grained model
- (2018) Gregory L. Dignon et al. PLoS Computational Biology
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II
- (2018) Huasong Lu et al. NATURE
- RNA polymerase II clustering through carboxy-terminal domain phase separation
- (2018) Marc Boehning et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Relation between single-molecule properties and phase behavior of intrinsically disordered proteins
- (2018) Gregory L. Dignon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
- (2018) Ann Boija et al. CELL
- The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity
- (2018) Fionna E. Loughlin et al. MOLECULAR CELL
- Phase separation drives heterochromatin domain formation
- (2017) Amy R. Strom et al. NATURE
- Direct observation of structure and dynamics during phase separation of an elastomeric protein
- (2017) Sean E. Reichheld et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
- (2017) Jacob P. Brady et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
- (2017) Susmitha Ambadipudi et al. Nature Communications
- Coexisting Liquid Phases Underlie Nucleolar Subcompartments
- (2016) Marina Feric et al. CELL
- Role of FET proteins in neurodegenerative disorders
- (2016) Francesca Svetoni et al. RNA Biology
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses
- (2016) Katannya Kapeli et al. Nature Communications
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Sequence- and Temperature-Dependent Properties of Unfolded and Disordered Proteins from Atomistic Simulations
- (2015) Gül H. Zerze et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
- (2015) Tetsuro Murakami et al. NEURON
- NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
- (2014) Woonghee Lee et al. BIOINFORMATICS
- Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms
- (2014) Tatyana A. Shelkovnikova et al. HUMAN MOLECULAR GENETICS
- A Time-Independent Free Energy Estimator for Metadynamics
- (2014) Pratyush Tiwary et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Temperature-dependent solvation modulates the dimensions of disordered proteins
- (2014) R. Wuttke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains
- (2013) Ilmin Kwon et al. CELL
- RNA Seeds Higher-Order Assembly of FUS Protein
- (2013) Jacob C. Schwartz et al. Cell Reports
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2
- (2012) J. C. Schwartz et al. GENES & DEVELOPMENT
- RNA targets of wild-type and mutant FET family proteins
- (2011) Jessica I Hoell et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
- (2011) C. P. Brangwynne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS
- (2011) Zhihui Sun et al. PLOS BIOLOGY
- Kinetics of Amyloid β Monomer-to-Oligomer Exchange by NMR Relaxation
- (2010) Nicolas L. Fawzi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enhanced Sampling in the Well-Tempered Ensemble
- (2010) M. Bonomi et al. PHYSICAL REVIEW LETTERS
- Temperature-dependent structural changes in intrinsically disordered proteins: Formation of α-helices or loss of polyproline II?
- (2010) Magnus Kjaergaard et al. PROTEIN SCIENCE
- CHARMM: The biomolecular simulation program
- (2009) B. R. Brooks et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Simulation of Osmotic Pressure in Concentrated Aqueous Salt Solutions
- (2009) Yun Luo et al. Journal of Physical Chemistry Letters
- EASY ROESY: Reliable Cross-Peak Integration in Adiabatic Symmetrized ROESY
- (2008) Christina M. Thiele et al. CHEMISTRY-A EUROPEAN JOURNAL
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions
- (2008) Andreas Vitalis et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Structure and Dynamics of the Aβ21–30Peptide from the Interplay of NMR Experiments and Molecular Simulations
- (2008) Nicolas L. Fawzi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Well-Tempered Metadynamics: A Smoothly Converging and Tunable Free-Energy Method
- (2008) Alessandro Barducci et al. PHYSICAL REVIEW LETTERS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now