Engineered human blood–brain barrier microfluidic model for vascular permeability analyses
出版年份 2022 全文链接
标题
Engineered human blood–brain barrier microfluidic model for vascular permeability analyses
作者
关键词
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出版物
Nature Protocols
Volume 17, Issue 1, Pages 95-128
出版商
Springer Science and Business Media LLC
发表日期
2022-01-08
DOI
10.1038/s41596-021-00635-w
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination
- (2021) Giovanni S. Offeddu et al. Communications Biology
- Microheart: A microfluidic pump for functional vascular culture in microphysiological systems
- (2021) Giovanni S. Offeddu et al. JOURNAL OF BIOMECHANICS
- Biology and Models of the Blood–Brain Barrier
- (2021) Cynthia Hajal et al. Annual Review of Biomedical Engineering
- The CCL2-CCR2 astrocyte-cancer cell axis in tumor extravasation at the brain
- (2021) Cynthia Hajal et al. Science Advances
- Evaluation of 1‐mm‐diameter endothelialized dense collagen tubes in vascular microsurgery
- (2020) Xuanyue Li et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
- Modeling Nanocarrier Transport across a 3D In Vitro Human Blood‐Brain–Barrier Microvasculature
- (2020) Sharon Wei Ling Lee et al. Advanced Healthcare Materials
- Endothelial Regulation of Drug Transport in a 3D Vascularized Tumor Model
- (2020) Kristina Haase et al. ADVANCED FUNCTIONAL MATERIALS
- The effects of luminal and trans-endothelial fluid flows on the extravasation and tissue invasion of tumor cells in a 3D in vitro microvascular platform
- (2020) Cynthia Hajal et al. BIOMATERIALS
- DDEL-04. ENGINEERED NANOCARRIERS TO ENHANCE DRUG DELIVERY ACROSS THE BLOOD-BRAIN BARRIER
- (2020) Joelle P Straehla et al. NEURO-ONCOLOGY
- Application of an in vitro Blood Brain Barrier model in the Selection of Experimental Drug Candidates for the Treatment of Huntington’s Disease
- (2019) Annalise Di Marco et al. MOLECULAR PHARMACEUTICS
- THER-15. FUNCTIONALIZED NANOPARTICLE TRAFFICKING ASSESSED IN A NOVEL MICROFLUIDIC MODEL OF THE BLOOD-BRAIN BARRIER WITH HIGH GRADE GLIOMA SPHEROIDS
- (2019) Joelle P Straehla et al. NEURO-ONCOLOGY
- Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications
- (2019) Gad D. Vatine et al. Cell Stem Cell
- A Novel Transwell Blood Brain Barrier Model Using Primary Human Cells
- (2019) Nicole L. Stone et al. Frontiers in Cellular Neuroscience
- An on-chip model of protein paracellular and transcellular permeability in the microcirculation
- (2019) Giovanni S. Offeddu et al. BIOMATERIALS
- Application of Transmural Flow Across In Vitro Microvasculature Enables Direct Sampling of Interstitial Therapeutic Molecule Distribution
- (2019) Giovanni S. Offeddu et al. Small
- Generation of blood vessel organoids from human pluripotent stem cells
- (2019) Reiner A. Wimmer et al. Nature Protocols
- Pericytes Contribute to Dysfunction in a Human 3D Model of Placental Microvasculature through VEGF‐Ang‐Tie2 Signaling
- (2019) Kristina Haase et al. Advanced Science
- 3D brain angiogenesis model to reconstitute functional human blood–brain barrier in vitro
- (2019) Somin Lee et al. BIOTECHNOLOGY AND BIOENGINEERING
- Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain
- (2019) Susanne J. van Veluw et al. NEURON
- 3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes
- (2018) Marco Campisi et al. BIOMATERIALS
- In vitro models of molecular and nano-particle transport across the blood-brain barrier
- (2018) Cynthia Hajal et al. Biomicrofluidics
- Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation
- (2018) Michelle B. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction
- (2018) Sofie Fogh Hedegaard et al. Scientific Reports
- Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture
- (2018) Ruth Olmer et al. Stem Cell Reports
- Bevacizumab and Glioblastoma
- (2018) Michelle M. Kim et al. CANCER JOURNAL
- Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood–brain barrier
- (2018) Nikolay Kutuzov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nanobody immunostaining for correlated light and electron microscopy with preservation of ultrastructure
- (2018) Tao Fang et al. NATURE METHODS
- A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier
- (2017) Giulia Adriani et al. LAB ON A CHIP
- On-chip human microvasculature assay for visualization and quantification of tumor cell extravasation dynamics
- (2017) Michelle B Chen et al. Nature Protocols
- Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis
- (2017) Benjamin J. Andreone et al. NEURON
- Influence of surface geometry on the culture of human cell lines: A comparative study using flat, round-bottom and v-shaped 96 well plates
- (2017) Sara Shafaie et al. PLoS One
- Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening
- (2016) Ying I. Wang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Physical and Chemical Signals That Promote Vascularization of Capillary-Scale Channels
- (2016) Raleigh M. Linville et al. Cellular and Molecular Bioengineering
- Electrospun gelatin biopapers as substrate forin vitrobilayer models of blood−brain barrier tissue
- (2016) Lauren L. Bischel et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Pitfalls in assessing microvascular endothelial barrier function: impedance-based devices versus the classic macromolecular tracer assay
- (2016) Iris Bischoff et al. Scientific Reports
- Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip
- (2016) Anna Herland et al. PLoS One
- Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor
- (2015) Jacquelyn A. Brown et al. Biomicrofluidics
- Quantification of Blood-Brain Barrier Solute Permeability and Brain Transport by Multiphoton Microscopy
- (2013) Lingyan Shi et al. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
- Microfluidic transwell inserts for generation of tissue culture-friendly gradients in well plates
- (2013) Christopher G. Sip et al. LAB ON A CHIP
- Antibody biodistribution coefficients
- (2013) Dhaval K. Shah et al. mAbs
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels
- (2012) Yoojin Shin et al. Nature Protocols
- The role of shear stress in Blood-Brain Barrier endothelial physiology
- (2011) Luca Cucullo et al. BMC NEUROSCIENCE
- Cytokine Signaling Modulates Blood-Brain Barrier Function
- (2011) Weihong Pan et al. CURRENT PHARMACEUTICAL DESIGN
- Bevacizumab for Malignant Gliomas
- (2010) Fabio M. Iwamoto et al. ARCHIVES OF NEUROLOGY
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies
- (2008) Birk Poller et al. JOURNAL OF NEUROCHEMISTRY
- Non-invasive measurement of solute permeability in cerebral microvessels of the rat
- (2008) Wei Yuan et al. MICROVASCULAR RESEARCH
- Preclinical Studies To Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution
- (2008) Marina A. Dobrovolskaia et al. MOLECULAR PHARMACEUTICS
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