The ancillary effects of nanoparticles and their implications for nanomedicine

Nanoparticle-Induced Complement Activation: Implications for Cancer Nanomedicine

(2021) Ninh M. La-Beck et al.   Frontiers in Immunology

Titanium dioxide nanoparticles enhance thrombosis through triggering the phosphatidylserine exposure and procoagulant activation of red blood cells

(2021) Yiying Bian et al.   Particle and Fibre Toxicology

Alginate-coated chitosan nanoparticles act as effective adjuvant for hepatitis A vaccine in mice

(2020) Nourhan H. AbdelAllah et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Machine learning predicts the functional composition of the protein corona and the cellular recognition of nanoparticles

(2020) Zhan Ban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic Review of Biodegradable Nanomaterials in Nanomedicine

(2020) Shi Su et al.   Nanomaterials

Lipid Nanoparticle Acts as a Potential Adjuvant for Influenza Split Vaccine without Inducing Inflammatory Responses

(2020) Seiki Shirai et al.   Vaccines

Antigen- and Epitope-Delivering Nanoparticles Targeting Liver Induce Comparable Immunotolerance in Allergic Airway Disease and Anaphylaxis as Nanoparticle-Delivering Pharmaceuticals

(2020) Qi Liu et al.   ACS Nano

Inducing immune tolerance with dendritic cell-targeting nanomedicines

(2020) Anna Cifuentes-Rius et al.   Nature Nanotechnology

‘Adhesion and release’ nanoparticle-mediated efficient inhibition of platelet activation disrupts endothelial barriers for enhanced drug delivery in tumors

(2020) Jinxu Cao et al.   BIOMATERIALS

Protein Corona Fingerprints of Liposomes: New Opportunities for Targeted Drug Delivery and Early Detection in Pancreatic Cancer

(2019) Sara Palchetti et al.   Pharmaceutics

FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels

(2019) Vicenta Trujillo-Alonso et al.   Nature Nanotechnology

Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness

(2019) Fei Peng et al.   Nature Nanotechnology

Impact of Short-Term Exposure of AuNCs on the Gut Microbiota of BALB/c Mice

(2019) Lirui Wang et al.   Journal of Biomedical Nanotechnology

Use of Polymeric Nanoparticle Platform Targeting the Liver To Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model

(2019) Qi Liu et al.   ACS Nano

Optimizing PLG nanoparticle-peptide delivery platforms for transplantation tolerance using an allogeneic skin transplant model

(2019) Sahil Shah et al.   BIOMATERIALS

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

(2019) Erick Riquelme et al.   CELL

The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL

(2019) Berk Aykut et al.   NATURE

Erythrocyte leveraged chemotherapy (ELeCt): Nanoparticle assembly on erythrocyte surface to combat lung metastasis

(2019) Zongmin Zhao et al.   Science Advances

Proteomic investigation on bio-corona of Au, Ag and Fe nanoparticles for the discovery of triple negative breast cancer serum protein biomarkers

(2019) María del Pilar Chantada-Vázquez et al.   Journal of Proteomics

Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier

(2018) Alysia Cox et al.   ACS Nano

Unintended effects of drug carriers: Big issues of small particles

(2018) Hamideh Parhiz et al.   ADVANCED DRUG DELIVERY REVIEWS

Responses of intestinal virome to silver nanoparticles: safety assessment by classical virology, whole-genome sequencing and bioinformatics approaches

(2018) Kuppan Gokulan et al.   International Journal of Nanomedicine

Liposome-induced immunosuppression and tumor growth is mediated by macrophages and mitigated by liposome-encapsulated alendronate

(2018) Robin Rajan et al.   JOURNAL OF CONTROLLED RELEASE

Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro

(2018) Barry Neun et al.   MOLECULES

Current understanding of the human microbiome

(2018) Jack A Gilbert et al.   NATURE MEDICINE

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

(2018) Jacob S. Brenner et al.   Nature Communications

The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression

(2018) Smruti Pushalkar et al.   Cancer Discovery

Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles

(2018) Riley P. Allen et al.   ACS Biomaterials-Science & Engineering

Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles

(2018) Riley P. Allen et al.   ACS Biomaterials Science & Engineering

Oral administration of rutile and anatase TiO2 nanoparticles shifts mouse gut microbiota structure

(2018) Juan Li et al.   Nanoscale

Minimum information reporting in bio–nano experimental literature

(2018) Matthew Faria et al.   Nature Nanotechnology

Transport and interactions of nanoparticles in the kidneys

(2018) Bujie Du et al.   Nature Reviews Materials

Insight into the preformed albumin corona on in vitro and in vivo performances of albumin-selective nanoparticles

(2018) Zhenbao Li et al.   Asian Journal of Pharmaceutical Sciences

Emerging Role of Immunosuppression in Diseases Induced by Micro- and Nano-Particles: Time to Revisit the Exclusive Inflammatory Scenario

(2018) François Huaux   Frontiers in Immunology

Effects of TiO2 nanoparticles and sunscreens on coastal marine microalgae: Ultraviolet radiation is key variable for toxicity assessment

(2017) M. Sendra et al.   ENVIRONMENT INTERNATIONAL

Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo

(2017) Zhen Yan et al.   International Journal of Nanomedicine

Protein corona: a new approach for nanomedicine design

(2017) Van Hong Nguyen et al.   International Journal of Nanomedicine

Tuning complement activation and pathway through controlled molecular architecture of dextran chains in nanoparticle corona

(2017) Jean-Baptiste Coty et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Scavenger Receptor Type B1 and Lipoprotein Nanoparticle Inhibit Myeloid-Derived Suppressor Cells

(2017) Michael P. Plebanek et al.   MOLECULAR CANCER THERAPEUTICS

Deformable Discoidal Polymeric Nanoconstructs for the Precise Delivery of Therapeutic and Imaging Agents

(2017) Anna Lisa Palange et al.   MOLECULAR THERAPY

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

(2017) Vinod P. Balachandran et al.   NATURE

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

(2017) Peter Popp Wibroe et al.   Nature Nanotechnology

Gut Dysbiosis and Neurobehavioral Alterations in Rats Exposed to Silver Nanoparticles

(2017) Angela B. Javurek et al.   Scientific Reports

Pro-Inflammatory versus Immunomodulatory Effects of Silver Nanoparticles in the Lung: The Critical Role of Dose, Size and Surface Modification

(2017) Francesca Alessandrini et al.   Nanomaterials

Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth

(2016) Sounik Saha et al.   ACS Nano

Distinct in vitro Complement Activation by Various Intravenous Iron Preparations

(2016) Julia Cordelia Hempel et al.   AMERICAN JOURNAL OF NEPHROLOGY

Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population

(2016) Qi Yang et al.   ANALYTICAL CHEMISTRY

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

(2016) Bing-Mae Chen et al.   ANALYTICAL CHEMISTRY

Rational Design of a Transferrin-Binding Peptide Sequence Tailored to Targeted Nanoparticle Internalization

(2016) Melissa Santi et al.   BIOCONJUGATE CHEMISTRY

Synthetic high-density lipoprotein-like nanoparticles potently inhibit cell signaling and production of inflammatory mediators induced by lipopolysaccharide binding Toll-like receptor 4

(2016) Linda Foit et al.   BIOMATERIALS

Multiwalled carbon nanotubes intratracheally instilled into the rat lung induce development of pleural malignant mesothelioma and lung tumors

(2016) Masumi Suzui et al.   CANCER SCIENCE

The Role of Carrier Geometry in Overcoming Biological Barriers to Drug Delivery

(2016) Carolyn Jordan et al.   CURRENT PHARMACEUTICAL DESIGN

Effects of zinc oxide nanoparticle dispersants on cytotoxicity and cellular uptake

(2016) Mi-Rae Jo et al.   Molecular & Cellular Toxicology

Endotoxin contamination: a key element in the interpretation of nanosafety studies

(2016) Yang Li et al.   Nanomedicine

An iron age for cancer therapy

(2016) Amy Tarangelo et al.   Nature Nanotechnology

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

(2016) Sung Eun Kim et al.   Nature Nanotechnology

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

Effect of surface chemistry and morphology of gold nanoparticle on the structure and activity of common blood proteins

(2016) Abhishek Chaudhary et al.   NEW JOURNAL OF CHEMISTRY

Biodegradable antigen-associated PLG nanoparticles tolerize Th2-mediated allergic airway inflammation pre- and postsensitization

(2016) Charles B. Smarr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel lipid nanoparticle adjuvant significantly enhances B cell and T cell responses to sub-unit vaccine antigens

(2016) Gokul Swaminathan et al.   VACCINE

Toward understanding the mechanism underlying the strong adjuvant activity of aluminum salt nanoparticles

(2016) Tinashe B. Ruwona et al.   VACCINE

The Effect of Polymeric Nanoparticles on Biocompatibility of Carrier Red Blood Cells

(2016) Daniel Pan et al.   PLoS One

Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake

(2015) Swetha Inturi et al.   ACS Nano

The “Sweet” Side of the Protein Corona: Effects of Glycosylation on Nanoparticle–Cell Interactions

(2015) Sha Wan et al.   ACS Nano

Rapid and Persistent Delivery of Antigen by Lymph Node Targeting PRINT Nanoparticle Vaccine Carrier To Promote Humoral Immunity

(2015) Sarah N. Mueller et al.   MOLECULAR PHARMACEUTICS

Enhanced biostability of nanoparticle-based drug delivery systems by albumin corona

(2015) Qiang Peng et al.   Nanomedicine

Characterization of the bionano interface and mapping extrinsic interactions of the corona of nanomaterials

(2015) D. J. O'Connell et al.   Nanoscale

Interactions of PLGA nanoparticles with blood components: protein adsorption, coagulation, activation of the complement system and hemolysis studies

(2015) Cristina Fornaguera et al.   Nanoscale

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

Mapping protein binding sites on the biomolecular corona of nanoparticles

(2015) Philip M. Kelly et al.   Nature Nanotechnology

Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice

(2015) Ching-Hao Li et al.   TOXICOLOGICAL SCIENCES

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

The fate of a designed protein corona on nanoparticles in vitro and in vivo

(2015) Denise Bargheer et al.   Beilstein Journal of Nanotechnology

Quantitative Analysis of the Enhanced Permeation and Retention (EPR) Effect

(2015) Andrew D. Wong et al.   PLoS One

Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles

(2014) Carl D. Walkey et al.   ACS Nano

Erythrocyte Membrane Is an Alternative Coating to Polyethylene Glycol for Prolonging the Circulation Lifetime of Gold Nanocages for Photothermal Therapy

(2014) Ji-Gang Piao et al.   ACS Nano

Nanoparticle delivery of donor antigens for transplant tolerance in allogeneic islet transplantation

(2014) Jane Bryant et al.   BIOMATERIALS

Changes of serum parameters of TiO2 nanoparticle-induced atherosclerosis in mice

(2014) Xiaohong Yu et al.   JOURNAL OF HAZARDOUS MATERIALS

Effects of subchronic exposure of silver nanoparticles on intestinal microbiota and gut-associated immune responses in the ileum of Sprague-Dawley rats

(2014) Katherine Williams et al.   Nanotoxicology

Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum

(2014) Nirmal K Banda et al.   Particle and Fibre Toxicology

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

(2014) D. R. Getts et al.   Science Translational Medicine

Engineering Biomaterial-Associated Complement Activation to Improve Vaccine Efficacy

(2013) Yuan Liu et al.   BIOMACROMOLECULES

Preformed albumin corona, a protective coating for nanoparticles based drug delivery system

(2013) Qiang Peng et al.   BIOMATERIALS

Aluminum hydroxide nanoparticles show a stronger vaccine adjuvant activity than traditional aluminum hydroxide microparticles

(2013) Xinran Li et al.   JOURNAL OF CONTROLLED RELEASE

The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes

(2013) Fengjuan Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Inhibition of tumor growth and metastasis by a self-therapeutic nanoparticle

(2013) R. R. Arvizo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE–cadherin

(2013) M.I. Setyawati et al.   Nature Communications

Cationic PAMAM Dendrimers Aggressively Initiate Blood Clot Formation

(2012) Clinton F. Jones et al.   ACS Nano

The antithrombotic and antimicrobial properties of PEG-protected silver nanoparticle coated surfaces

(2012) V.M. Ragaseema et al.   BIOMATERIALS

Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats

(2012) Jiegou Xu et al.   CANCER SCIENCE

Zinc oxide nanoflowers make new blood vessels

(2012) Ayan Kumar Barui et al.   Nanoscale

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Effect of gold nanoparticle morphology on adsorbed protein structure and function

(2011) Jennifer E. Gagner et al.   BIOMATERIALS

Aqueous fullerene aggregates (nC60) generate minimal reactive oxygen species and are of low toxicity in fish: a revision of previous reports

(2011) Theodore B Henry et al.   CURRENT OPINION IN BIOTECHNOLOGY

Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

(2011) Miriam Benezra et al.   JOURNAL OF CLINICAL INVESTIGATION

Chitosan as an adjuvant for poliovaccine

(2011) Y. Ghendon et al.   JOURNAL OF MEDICAL VIROLOGY

Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and AmBisome

(2011) János Szebeni et al.   Nanomedicine-Nanotechnology Biology and Medicine

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Antiplatelet Properties of Silver Nanoparticles

(2009) Siddhartha Shrivastava et al.   ACS Nano

Inhaled carbon nanotubes reach the subpleural tissue in mice

(2009) Jessica P. Ryman-Rasmussen et al.   Nature Nanotechnology

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

(2008) Michelle Longmire et al.   Nanomedicine

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Strain specificity in antimicrobial activity of silver and copper nanoparticles

(2007) Jayesh P. Ruparelia et al.   Acta Biomaterialia