Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation

Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

(2021) Jeremy Goc et al.   CELL

E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis

(2021) Jay V. Patankar et al.   NATURE CELL BIOLOGY

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

(2020) Nick Powell et al.   GUT

The development of colitis in Il10−/− mice is dependent on IL-22

(2020) Dilini C. Gunasekera et al.   Mucosal Immunology

Pathway paradigms revealed from the genetics of inflammatory bowel disease

(2020) Daniel B. Graham et al.   NATURE

Cell death in the gut epithelium and implications for chronic inflammation

(2020) Jay V. Patankar et al.   Nature Reviews Gastroenterology & Hepatology

Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation

(2019) Aimée Parker et al.   Cell Death & Disease

Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease

(2019) Matthias Friedrich et al.   IMMUNITY

IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation

(2019) Wenjun Ouyang et al.   IMMUNITY

Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2

(2019) Lei Zhou et al.   NATURE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

A circadian clock is essential for homeostasis of group 3 innate lymphoid cells in the gut

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Heparin-Binding Epidermal Growth Factor–Like Growth Factor as a Critical Mediator of Tissue Repair and Regeneration

(2018) Duy T. Dao et al.   AMERICAN JOURNAL OF PATHOLOGY

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

Autocrine–paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling

(2018) Darren J. Perkins et al.   NATURE IMMUNOLOGY

Current and emerging therapeutic targets for IBD

(2017) Markus F. Neurath   Nature Reviews Gastroenterology & Hepatology

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium

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RORγt, a multitask nuclear receptor at mucosal surfaces

(2016) G Eberl   Mucosal Immunology

Expression and Function of the Epidermal Growth Factor Receptor in Physiology and Disease

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The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

(2015) George D. Kalliolias et al.   Nature Reviews Rheumatology

IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin–EGFR interactions

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Pleiotropic functions of TNF-  in the regulation of the intestinal epithelial response to inflammation

(2014) M. Leppkes et al.   INTERNATIONAL IMMUNOLOGY

TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction

(2014) F Van Hauwermeiren et al.   Mucosal Immunology

Trafficking of Epidermal Growth Factor Receptor Ligands in Polarized Epithelial Cells

(2013) Bhuminder Singh et al.   Annual Review of Physiology

Suppression of Inflammation with Conditional Deletion of the Prostaglandin E2 EP2 Receptor in Macrophages and Brain Microglia

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Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

(2013) Jochem H Bernink et al.   NATURE IMMUNOLOGY

Clinical targeting of the TNF and TNFR superfamilies

(2013) Michael Croft et al.   NATURE REVIEWS DRUG DISCOVERY

Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium

(2012) Claudia Günther et al.   GUT

Multifaceted roles of PGE2 in inflammation and cancer

(2012) Masako Nakanishi et al.   Seminars in Immunopathology

TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival

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Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

(2008) Djahida Bouskra et al.   NATURE