Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction
出版年份 2021 全文链接
标题
Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction
作者
关键词
-
出版物
Nature Chemistry
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-12-17
DOI
10.1038/s41557-021-00833-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Asymmetric Catalysis Mediated by Synthetic Peptides, Version 2.0: Expansion of Scope and Mechanisms
- (2020) Anthony J. Metrano et al. CHEMICAL REVIEWS
- Computational Design of Multisubstrate Enzyme Specificity
- (2019) Antony D. St-Jacques et al. ACS Catalysis
- DIALS: implementation and evaluation of a new integration package
- (2018) Graeme Winter et al. Acta Crystallographica Section D-Structural Biology
- Endohedral Functionalized Cage as a Tool to Create Frustrated Lewis Pairs
- (2018) Alexandre Martinez et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Evolution of a highly active and enantiospecific metalloenzyme from short peptides
- (2018) Sabine Studer et al. SCIENCE
- Rational design of proteins that exchange on functional timescales
- (2017) James A Davey et al. Nature Chemical Biology
- Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions
- (2017) Yongho Park et al. SCIENCE
- Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase
- (2016) Richard Obexer et al. Nature Chemistry
- Protein self-assembly induces promiscuous nucleophilic biocatalysis in Morita–Baylis–Hillman (MBH) reaction
- (2016) Pralhad N. Joshi et al. RSC Advances
- Concerted versus Stepwise Mechanism in Thymidylate Synthase
- (2014) Zahidul Islam et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Computational Design of Enone-Binding Proteins with Catalytic Activity for the Morita–Baylis–Hillman Reaction
- (2013) Sinisa Bjelic et al. ACS Chemical Biology
- Design of Protein Catalysts
- (2013) Donald Hilvert Annual Review of Biochemistry
- Recent Advances in Organocatalytic Asymmetric Morita–Baylis–Hillman/aza-Morita–Baylis–Hillman Reactions
- (2013) Yin Wei et al. CHEMICAL REVIEWS
- Precision is essential for efficient catalysis in an evolved Kemp eliminase
- (2013) Rebecca Blomberg et al. NATURE
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Increased Diels-Alderase activity through backbone remodeling guided by Foldit players
- (2012) Christopher B Eiben et al. NATURE BIOTECHNOLOGY
- Reducing Codon Redundancy and Screening Effort of Combinatorial Protein Libraries Created by Saturation Mutagenesis
- (2012) Sabrina Kille et al. ACS Synthetic Biology
- Use of Protease from Bacillus licheniformis as Promiscuous Catalyst for Organic Synthesis: Applications in CC and CN Bond Formation Reactions
- (2011) María López-Iglesias et al. ADVANCED SYNTHESIS & CATALYSIS
- A highly efficient kinetic resolution of Morita–Baylis–Hillman adducts achieved by N–Ar axially chiral Pd-complexes catalyzed asymmetric allylation
- (2011) Feijun Wang et al. CHEMICAL COMMUNICATIONS
- Effect of the damping function in dispersion corrected density functional theory
- (2011) Stefan Grimme et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Asymmetric Morita–Baylis–Hillman reactions of 2-cyclohexen-1-one catalyzed by chiral biaryl-based bis(thiourea) organocatalysts
- (2011) Yuki Nakayama et al. TETRAHEDRON LETTERS
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Recent Contributions from the Baylis−Hillman Reaction to Organic Chemistry
- (2010) Deevi Basavaiah et al. CHEMICAL REVIEWS
- Enantioselective Thiourea-Catalyzed Cationic Polycyclizations
- (2010) Robert R. Knowles et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
- (2010) J. B. Siegel et al. SCIENCE
- Brønsted Acid Catalyzed Morita-Baylis-Hillman Reaction: A New Mechanistic View for Thioureas Revealed by ESI-MS(/MS) Monitoring and DFT Calculations
- (2009) Giovanni W. Amarante et al. CHEMISTRY-A EUROPEAN JOURNAL
- Stability effects of mutations and protein evolvability
- (2009) Nobuhiko Tokuriki et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
- (2009) Garrett M. Morris et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Nuclear Quantum Tunneling in the Light-activated Enzyme Protochlorophyllide Oxidoreductase
- (2008) Derren J. Heyes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Kemp elimination catalysts by computational enzyme design
- (2008) Daniela Röthlisberger et al. NATURE
- Asymmetric Morita-Baylis-Hillman Reaction of Arylaldehydes with 2-Cyclohexen-1-one Catalyzed by Chiral Bis(Thio)urea and DABCO
- (2008) Min Shi et al. ORGANIC LETTERS
- De Novo Computational Design of Retro-Aldol Enzymes
- (2008) L. Jiang et al. SCIENCE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started