A naturally inspired antibiotic to target multidrug-resistant pathogens

Neisseria gonorrhoeae Antimicrobial Resistance: Past to Present to Future

(2021) Georgina L. Aitolo et al.   CURRENT MICROBIOLOGY

Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9

(2020) Zhuoren Ling et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synthetic-Bioinformatic Natural Product Antibiotics with Diverse Modes of Action

(2020) John Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

7-Hydroxycoumarin Attenuates Colistin-Induced Kidney Injury in Mice Through the Decreased Level of Histone Deacetylase 1 and the Activation of Nrf2 Signaling Pathway

(2020) Jian Wang et al.   Frontiers in Pharmacology

Colistin heteroresistance in Enterobacter cloacae is regulated by Pho PQ ‐dependent 4‐amino‐4‐deoxy‐ l ‐arabinose addition to lipid A

(2019) Katie N. Kang et al.   MOLECULAR MICROBIOLOGY

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

(2019) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Advances in microbial culturing conditions to activate silent biosynthetic gene clusters for novel metabolite production

(2019) Hailey A. Tomm et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Bioactive Synthetic-Bioinformatic Natural Product Cyclic Peptides Inspired by Nonribosomal Peptide Synthetase Gene Clusters from the Human Microbiome

(2019) John Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new antibiotic selectively kills Gram-negative pathogens

(2019) Yu Imai et al.   NATURE

Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NS

(2018) Deanna Deveson Lucas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

(2018) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Resistance to polymyxins in Gram-negative organisms

(2017) Katy Jeannot et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

MCR-1-producing Klebsiella pneumoniae outbreak in China

(2017) Guo-Bao Tian et al.   LANCET INFECTIOUS DISEASES

Recent advances and perspectives in the design and development of polymyxins

(2017) Francesc Rabanal et al.   NATURAL PRODUCT REPORTS

LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

(2017) Jun-Rong Wei et al.   mSphere

Transferable resistance to colistin: a new but old threat: Table 1.

(2016) Stefan Schwarz et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

(2016) Yi-Yun Liu et al.   LANCET INFECTIOUS DISEASES

Discovery of MRSA active antibiotics using primary sequence from the human microbiome

(2016) John Chu et al.   Nature Chemical Biology

Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606

(2016) Daryl L. Richie et al.   PLoS One

Characterization of an Acinetobacter baumanniilptDDeletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis

(2015) Jade Bojkovic et al.   JOURNAL OF BACTERIOLOGY

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

(2015) Peter J. Rutledge et al.   NATURE REVIEWS MICROBIOLOGY

Colistin: an update on the antibiotic of the 21st century

(2012) Silpak Biswas et al.   Expert Review of Anti-Infective Therapy

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

(2010) J. H. Moffatt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Neutrophil Gelatinase–Associated Lipocalin (NGAL) as a Marker of Kidney Damage

(2008) Davide Bolignano et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Neutrophil gelatinase‐associated lipocalin (NGAL): A new marker of kidney disease

(2008) Peasad Devarajan   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION