Neuroinflammation in the Cerebellum and Brainstem in Friedreich Ataxia: An [ 18 F ]‐ FEMPA PET Study

Longitudinal structural brain changes in Friedreich ataxia depend on disease severity: the IMAGE-FRDA study

(2021) Louisa P. Selvadurai et al.   JOURNAL OF NEUROLOGY

[11C]PK11195-PET Brain Imaging of the Mitochondrial Translocator Protein in Mitochondrial Disease

(2021) Jelle van den Ameele et al.   NEUROLOGY

Brain Structure and Degeneration Staging in Friedreich Ataxia: Magnetic Resonance Imaging Volumetrics from the ENIGMA‐Ataxia Working Group

(2021) Ian H. Harding et al.   ANNALS OF NEUROLOGY

[11C]PBR28 MR–PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder

(2020) N. R. Zürcher et al.   MOLECULAR PSYCHIATRY

A Drosophila model of Friedreich Ataxia with CRISPR/Cas9 insertion of GAA repeats in the frataxin gene reveals in vivo protection by N-acetyl cysteine

(2020) Maria Russi et al.   HUMAN MOLECULAR GENETICS

Central Nervous System Therapeutic Targets in Friedreich Ataxia

(2020) Ian H. Harding et al.   HUMAN GENE THERAPY

Longitudinal evaluation of iron concentration and atrophy in the dentate nuclei in friedreich ataxia

(2019) Phillip G. D. Ward et al.   MOVEMENT DISORDERS

Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders

(2019) Eryn L. Werry et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroinflammation — a common thread in neurological disorders

(2019) Nils Erik Gilhus et al.   Nature Reviews Neurology

Neuroinflammation in Huntington’s Disease: New Insights with 11C-PBR28 PET/MRI

(2018) Cristina Lois et al.   ACS Chemical Neuroscience

Integrated MRI and [11 C]-PBR28 PET Imaging in Amyotrophic Lateral sclerosis

(2018) Mohamad J. Alshikho et al.   ANNALS OF NEUROLOGY

Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich’s ataxia patients

(2018) Daniel Nachun et al.   HUMAN MOLECULAR GENETICS

Cerebral abnormalities in Friedreich ataxia: A review

(2018) Louisa P. Selvadurai et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Frataxin deficiency impairs mitochondrial biogenesis in cells, mice and humans

(2017) Mittal J. Jasoliya et al.   HUMAN MOLECULAR GENETICS

Sifting through the surfeit of neuroinflammation tracers

(2017) Paul Cumming et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Distinct patterns of increased translocator protein in posterior cortical atrophy and amnestic Alzheimer's disease

(2017) William C. Kreisl et al.   NEUROBIOLOGY OF AGING

In Vivo Imaging of Human Neuroinflammation

(2016) Daniel S. Albrecht et al.   ACS Chemical Neuroscience

The role of interleukin-6 signaling in nervous tissue

(2016) Michelle Rothaug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Early and protective microglial activation in Alzheimer’s disease: a prospective study using18F-DPA-714 PET imaging

(2016) Lorraine Hamelin et al.   BRAIN

A probabilistic atlas of the cerebellar white matter

(2016) K.M. van Baarsen et al.   NEUROIMAGE

Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34

(2016) Yan Shen et al.   PLoS One

Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation

(2016) Arnulf H. Koeppen et al.   Acta Neuropathologica Communications

Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

(2015) C. H. Lyoo et al.   JOURNAL OF NUCLEAR MEDICINE

Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: a cross-sectional analysis of baseline data

(2015) Kathrin Reetz et al.   LANCET NEUROLOGY

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer’s disease patients and control subjects

(2014) Andrea Varrone et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia

(2014) Genki Hayashi et al.   HUMAN MOLECULAR GENETICS

Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches

(2014) Inelia Morales et al.   Frontiers in Cellular Neuroscience

Dysregulation of cellular iron metabolism in Friedreich ataxia: from primary iron-sulfur cluster deficit to mitochondrial iron accumulation

(2014) Alain Martelli et al.   Frontiers in Pharmacology

Frataxin Deficiency Leads to Defects in Expression of Antioxidants and Nrf2 Expression in Dorsal Root Ganglia of the Friedreich's Ataxia YG8R Mouse Model

(2013) Yuxi Shan et al.   ANTIOXIDANTS & REDOX SIGNALING

Friedreich Ataxia: Neuropathology Revised

(2013) Arnulf H. Koeppen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Friedreich's Ataxia Causes Redistribution of Iron, Copper, and Zinc in the Dentate Nucleus

(2012) Arnulf H. Koeppen et al.   CEREBELLUM

A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation

(2012) William C Kreisl et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Clinical Features of Friedreich Ataxia

(2012) Martin B. Delatycki et al.   JOURNAL OF CHILD NEUROLOGY

FreeSurfer

(2012) Bruce Fischl   NEUROIMAGE

Imaging the deep cerebellar nuclei: A probabilistic atlas and normalization procedure

(2010) J. Diedrichsen et al.   NEUROIMAGE

Frataxin deficiency induces Schwann cell inflammation and death

(2009) Chunye Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The pathogenesis of Friedreich ataxia and the structure and function of frataxin

(2009) Massimo Pandolfo et al.   JOURNAL OF NEUROLOGY

Does neuroinflammation fan the flame in neurodegenerative diseases?

(2009) Tamy C Frank-Cannon et al.   Molecular Neurodegeneration

A probabilistic MR atlas of the human cerebellum

(2009) Jörn Diedrichsen et al.   NEUROIMAGE