Modulation of the NOTCH1 Pathway by LUNATIC FRINGE Is Dominant over That of MANIC or RADICAL FRINGE

Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2

(2020) Shinako Kakuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein O-fucosylation: structure and function

(2019) Bernadette C Holdener et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice

(2019) Shweta Varshney et al.   BMC DEVELOPMENTAL BIOLOGY

Effects of Notch glycosylation on health and diseases

(2019) Yusuke Urata et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Multiple Roles for O-Glycans in Notch Signalling

(2018) Shweta Varshney et al.   FEBS LETTERS

Two novel proteinO-glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling

(2018) Hideyuki Takeuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations

(2017) Brian J McMillan et al.   GLYCOBIOLOGY

O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking

(2017) Hideyuki Takeuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity

(2017) Vincent C. Luca et al.   SCIENCE

Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch

(2015) Wendy R. Gordon et al.   DEVELOPMENTAL CELL

Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development

(2015) Yinghui Song et al.   JOURNAL OF IMMUNOLOGY

Structural basis for Notch1 engagement of Delta-like 4

(2015) V. C. Luca et al.   SCIENCE

Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states

(2014) Lauren LeBon et al.   eLife

Fringe Controls Naïve CD4+T Cells Differentiation through Modulating Notch Signaling in Asthmatic Rat Models

(2012) Wen Gu et al.   PLoS One

A Mutation in EGF Repeat-8 of Notch Discriminates Between Serrate/Jagged and Delta Family Ligands

(2012) S. Yamamoto et al.   SCIENCE

Galactose Differentially Modulates Lunatic and Manic Fringe Effects on Delta1-induced NOTCH Signaling

(2011) Xinghua Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-Glucose Trisaccharide Is Present at High but Variable Stoichiometry at Multiple Sites on Mouse Notch1

(2011) Nadia A. Rana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-Dimensional Target Decoy Strategy for Shotgun Proteomics

(2011) Marshall W. Bern et al.   JOURNAL OF PROTEOME RESEARCH

Structural Insights into the Mechanism of Protein O-Fucosylation

(2011) Erandi Lira-Navarrete et al.   PLoS One

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain

(2009) Jennifer L. Moran et al.   DEVELOPMENTAL DYNAMICS

MFng Is Dispensable for Mouse Pancreas Development and Function

(2009) P. Svensson et al.   MOLECULAR AND CELLULAR BIOLOGY

A deficiency of lunatic fringe is associated with cystic dilation of the rete testis

(2008) K L Hahn et al.   REPRODUCTION