期刊
BIOINFORMATICS
卷 35, 期 21, 页码 4392-4393出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btz232
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资金
- Research Council of Norway [230338]
- Stiftelsen K.G. Jebsen
A Summary: Data from chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) generally contain either narrow peaks or broad and diffusely enriched domains. The SICER ChIP-seq caller has proven adept at finding diffuse domains in ChIP-seq data, but it is slow, requires much memory, needs manual installation steps and is hard to use. epic2 is a complete rewrite of SICER that is focused on speed, low memory overhead and ease-of-use.
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