Synthesis, in vitro and in silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides

Eco-friendly H2O2 oxidation of 1,2-dihydroquinazoline-3-oxides to quinazoline-3-oxides

(2021) Rashinikumar Samandram et al.   SYNTHETIC COMMUNICATIONS

The synthesis of isoxazolo[2,3-c]quinazolines via a cycloaddition of quinazoline-3-oxides and acrylates

(2020) Zhijian Yin et al.   TETRAHEDRON LETTERS

An Convenient Approach to 2,4-Disubstituted Quinazoline 3-Oxides Using active MnO2 as Oxidant

(2019) Yiyuan Peng et al.   CANADIAN JOURNAL OF CHEMISTRY

Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites

(2019) Zhiran Ju et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Human disorders associated with inflammation and the evolving role of natural products to overcome

(2019) Navneet Kishore et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, in vitro and in silico evaluation of novel trans -stilbene analogues as potential COX-2 inhibitors

(2018) Miłosz Regulski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

An overview of quinazolines: Pharmacological significance and recent developments

(2018) V. Alagarsamy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Thiazoles and Thiazolidinones as COX/LOX Inhibitors

(2018) et al.   MOLECULES

In vitro cytotoxicity of novel 2,5,7-tricarbo-substituted indoles derived from 2-amino-5-bromo-3-iodoacetophenone

(2016) Malose J. Mphahlele et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

(2016) Vibha Rani et al.   LIFE SCIENCES

Rh(III)- and Zn(II)-Catalyzed Synthesis of Quinazoline N-Oxides via C–H Amidation–Cyclization of Oximes

(2016) Qiang Wang et al.   ORGANIC LETTERS

Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?

(2016) Subrata Kumar Biswas   Oxidative Medicine and Cellular Longevity

Multimodal analgesia: A systematic review of local NSAIDs for non-ophthalmologic postoperative pain management

(2016) Lisa Brubaker et al.   International Journal of Surgery

Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity

(2015) Bing Liu et al.   Cancer Cell International

PLIP: fully automated protein–ligand interaction profiler

(2015) Sebastian Salentin et al.   NUCLEIC ACIDS RESEARCH

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

One-step method for synthesis of 2,4-disubstituted quinazoline 3-oxides by reaction of a 2-aminoaryl ketone with a hydroxamic acid using Zn(OTf)2 as the catalyst

(2014) Sridhar Madabhushi et al.   TETRAHEDRON LETTERS

Trifluoroacetic acid: Uses and recent applications in organic synthesis

(2013) Simón E. López et al.   JOURNAL OF FLUORINE CHEMISTRY

Visible light-mediated synthesis of quinazolines from 1,2-dihydroquinazoline 3-oxides

(2013) Yi-Chou Chen et al.   TETRAHEDRON

WinGXandORTEP for Windows: an update

(2012) Louis J. Farrugia   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

Synthesis ofN-Arylindazoles and Benzimidazoles from a Common Intermediate

(2010) Brenda C. Wray et al.   ORGANIC LETTERS

Structure validation in chemical crystallography

(2009) Anthony L. Spek   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Organocatalyzed Beckmann rearrangement of cyclohexanone oxime by trifluoroacetic acid in aprotic solvent

(2008) L RONCHIN et al.   CATALYSIS COMMUNICATIONS

A Practical, Metal-Free Synthesis of 1H-Indazoles

(2008) Carla M. Counceller et al.   ORGANIC LETTERS